The Giants will play the Mariners on Saturday, February 21st, 2026. Your timezone's first pitch time is 3:10 pm EST. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Giants at Mariners Odds
| Underdog Seattle Mariners | Favorite San Francisco Giants |
|---|---|
| Over | Under |
|---|---|
| Underdog Seattle Mariners | Favorite San Francisco Giants |
|---|---|
Matchup Odds FAQs
The San Francisco Giants are the -115 moneyline favorite at BetMGM and the Seattle Mariners are the -105 moneyline underdog at BetMGM.
The best over line is 10.5 +105 runs at BetMGM, which means you risk $100 to win $105 betting the over. The best under line is 10.5 -125 runs at BetMGM, and that means you risk $125 to win $100 betting the under.
The San Francisco Giants are -1.5 +140 run line favorites at BetMGM, while the Seattle Mariners are +1.5 -170 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Giants
Mariners
2/21/26 3:10pm EST | -115-105 |
- Seattle Mariners bettors risk $100 to win $95.24 at -105 odds. The implied probability for Seattle Mariners is 51.22%.
- San Francisco Giants bettors risk $100 to win $86.96 at -115 odds. The implied probability for San Francisco Giants is 53.49%.
San Francisco Giants at Seattle Mariners Prop Bets
| BetMGM Bet |
|
|---|---|
Giants
Mariners
2/21/26 3:10pm EST | Pending BetMGM |
San Francisco Giants & Seattle Mariners Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Francisco Giants World Series Odds|
Team | BetMGM |
|---|---|
| Giants | +6600 Bet |
|
Team | BetMGM |
|---|---|
| Mariners | +1300 Bet |
San Francisco Giants & Seattle Mariners Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| x - Seattle Mariners | 90 | 72 | 0.556 | +7.0 | 51-30 | 39-42 | 766 | 694 | +72 | L3 | 7-3 |
| e - San Francisco Giants | 81 | 81 | 0.500 | +16.0 | 42-39 | 39-42 | 705 | 684 | +21 | W4 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco Giants vs Seattle Mariners MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 21st, 2026 at 3:10 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Seattle Mariners Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Seattle Mariners Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other February 21, 2026 MLB Games
- Atlanta Braves vs Tampa Bay Rays
- Boston Red Sox vs Minnesota Twins
- Detroit Tigers vs New York Yankees
- Pittsburgh Pirates vs Baltimore Orioles
- Philadelphia Phillies vs Toronto Blue Jays
- Miami Marlins vs New York Mets
- Texas Rangers vs Chicago Cubs
- San Diego Padres vs Kansas City Royals
- Oakland Athletics vs Chicago White Sox
- Colorado Rockies vs Arizona Diamondbacks
- Los Angeles Dodgers vs Los Angeles Angels