San Francisco Giants vs Chicago White Sox Odds

The Giants will play the White Sox on Sunday, June 29th, 2025. Your timezone's first pitch time is 2:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the San Francisco Giants possess a 95.33 SportsBetting3.com power ranking. The Chicago White Sox now have a 85.67 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting San Francisco Giants - The San Francisco Giants head into this matchup with a 14-15 record as a visiting team. This standing ranks them 4th Overall for visiting team wins.
  • Home Chicago White Sox - The Chicago White Sox will throw the first pitch possessing a 12-15 home team record. That puts them 8th for home team wins in the Overall MLB standings.
  • Runs Scored - San Francisco Giants batters have produced 239 runs, ranking them 10th Overall, with the Chicago White Sox ranking 24th (183) for runs scored.
  • Runs Allowed - San Francisco Giants pitchers and fielders have allowed 199 runs, ranking them 22nd Overall for runs allowed. Meanwhile, the Chicago White Sox now rank 12th Overall, allowing 234 runs.
  • Team Streaks - The San Francisco Giants have lost their last 2 games. Their opponent, the Chicago White Sox have lost their last 2 games.
  • Team Records - Let's review each team's records. The San Francisco Giants have a 31-24 Overall record (3.0 GB National West Division), with the Chicago White Sox notching a 17-37 Overall standing (18.5 GB American Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Ye scurvy Giants be settin' sail to face the White Sox...

The Giants be lookin' to plunder a win on enemy shores...

The White Sox be no match for the swashbucklin' Giants crew...

Avast ye! Check out this game's prop bets below, bet on MLB baseball at legal US sportsbooks...

The Giants be holdin' strong with a record of 31-24...

The White Sox be sinkin' fast with a record of 17-37...

Both teams be needin' a victory to climb the standings...

Review each team's standin' at the bottom of the page, me hearties!

Best Giants at White Sox Odds


Best Moneyline Betting Odds
Underdog

Chicago White Sox
Favorite

San Francisco Giants
The San Francisco Giants are the -160 moneyline favorite. Risk $160 to win $100 on the San Francisco Giants at BetMGM. The Chicago White Sox are the +135 underdog at BetMGM. Risk $100 to win $135 on the Chicago White Sox. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $120 to win $100. BetMGM has the best under line of 8.5 runs. Risk $100 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Chicago White Sox
Favorite

San Francisco Giants
The San Francisco Giants have a -1.5 +105 run line at BetMGM OH. They are the run line favorite in this matchup. The Chicago White Sox have a +1.5 -125 run line at BetMGM OH. The Chicago White Sox are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Francisco Giants vs Chicago White Sox MLB game on Sunday, June 29th, 2025?

The San Francisco Giants are the -160 moneyline favorite at BetMGM and the Chicago White Sox are the +135 moneyline underdog at BetMGM.

What is the over-under total line for the San Francisco Giants vs Chicago White Sox MLB game on Sunday, June 29th, 2025?

The best over line is 8.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 8.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.

What is the run line for the San Francisco Giants vs Chicago White Sox MLB game on Sunday, June 29th, 2025?

The San Francisco Giants are -1.5 +105 run line favorites at BetMGM, while the Chicago White Sox are +1.5 -125 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Giants
White Sox
6/29/25 2:10pm EDT
-160+135
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966
Possible Moneyline Outcomes
  • Chicago White Sox bettors risk $100 to win $135 at +135 odds. The implied probability for Chicago White Sox is 42.55%.
  • San Francisco Giants bettors risk $100 to win $62.5 at -160 odds. The implied probability for San Francisco Giants is 61.54%.

San Francisco Giants at Chicago White Sox Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Giants
White Sox
First Team to Score
6/29/25 2:10pm EDT
-180+140Bet
Giants
White Sox
Tie
1st Inning Winner
6/29/25 2:10pm EDT
+260+320-130Bet
Giants
White Sox
Tie
First 3 Innings Winner
6/29/25 2:10pm EDT
+120+154+300Bet
Giants
White Sox
To Extra Innings
6/29/25 2:10pm EDT
Yes +775No -1400Bet
BetMGM Sports Betting BetMGM
Giants
White Sox
1st Team to Score Will Win
6/29/25 2:10pm EDT
Yes -250No +190Bet
Giants
Total Runs
SFO at CWS
6/29/25 2:10pm EDT
4.5 o -1254.5 u -105Bet
Jonathan Cannon
Strikeouts Thrown
SFO at CWS
6/29/25 2:10pm EDT
3.5 o +1303.5 u -165Bet
Justin Verlander
Strikeouts Thrown
SFO at CWS
6/29/25 2:10pm EDT
5.5 o +1255.5 u -160Bet

San Francisco Giants & Chicago White Sox Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds
2025 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+3300
Bet
Chicago White Sox World Series Odds
2025 Chicago White Sox World Series Odds

Team
BetMGM Sports Betting BetMGM
White Sox
+200000
Bet

San Francisco Giants & Chicago White Sox Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Francisco Giants, Chicago White Sox
Team W L Pct GB Home Away RS RA Diff Strk L10
San Francisco Giants31240.564+4.517-914-15239199+40L25-5
Chicago White Sox17370.315+18.012-155-22183234-51L23-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco Giants vs Chicago White Sox MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 29th, 2025 at 2:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Chicago White Sox Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Chicago White Sox Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other June 29, 2025 MLB Games

Odds Preview 13197