St. Louis Cardinals vs Cleveland Indians MLB Betting Lines

Odds Preview 2220

The Cardinals will play the Indians on Wednesday, July 28th, 2021 at 1:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers
  • Cardinals - K. Kim - L
  • Indians - Z. Plesac - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets
Underdog

Cleveland Indians
Favorite

St. Louis Cardinals
+100 Sb3gen1 -113 Sb3gen2
-105 Sb3gen3 -115 Sb3gen3
-107 Sb3gen2 -1008 Sb3gen1
Here are money lines for the outright winner. Favorite St. Louis Cardinals has a minus value. Lay $113 at Sb3gen2 to win $100. Underdog Cleveland Indians has a positive value. Risk $100 at Sb3gen1 to win $100.
Best Over and Under Total Lines
OverUnder
8.5o -120 Sb3gen1 9u -120 Sb3gen3
8.5o -120 Sb3gen2 8.5u +100 Sb3gen1
9o +100 Sb3gen3 8.5u +100 Sb3gen2
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 8.5 points laying $120 to win $100. Sb3gen3 has the best under line of 9 u -120.
Best Underdog and Favorite Run Line Bets
Underdog

St. Louis Cardinals
Favorite

Cleveland Indians
+1.5 -195 Sb3gen1 -1.5 +170 Sb3gen1
+1.5 -200 Sb3gen2 -1.5 +170 Sb3gen2
+1.5 -200 Sb3gen3 -1.5 +170 Sb3gen3
SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Sb3gen1 has the best favorite Cleveland Indians run line at -1.5 points. Sb3gen1 has the best underdog St. Louis Cardinals run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
OutcomeSB3Gen SB3Gen

Cached 2022-01-20 07:01:50
Cleveland Indians World Series Odds
OutcomeSB3Gen SB3Gen

Cached 2022-01-20 07:01:50

Team Standings

Season Standings
Team W L Pct GB Home Away Strk L10
St. Louis Cardinals
90 72 0.556 17.0 90-72 45-36 L2 79-63
Cleveland Indians
80 82 0.494 27.0 80-82 40-41 W1 71-71

St. Louis Cardinals Batting Stats

2021 St. Louis Cardinals Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Tommy Edman
2B
160 91 168 11 56 38 95 0.262
Paul Goldschmidt
1B
158 102 177 31 99 67 136 0.294
Nolan Arenado
3B
157 81 151 34 105 50 96 0.255
Dylan Carlson
RF
151 79 144 18 65 57 152 0.266
Tyler O'Neill
LF
141 89 138 34 80 38 168 0.286
Matt Carpenter
2B
130 18 35 3 21 35 77 0.169
Yadier Molina
C
121 45 111 11 66 24 79 0.252
Paul DeJong
SS
114 44 70 19 45 35 103 0.197
Edmundo Sosa
SS
113 39 78 6 27 17 63 0.271
Harrison Bader
CF
103 45 98 16 50 27 85 0.267
Giovanny Gallegos
RP
73 0 0 0 0 0 0 0.000
Genesis Cabrera
RP
71 0 0 0 0 0 0 0.000

Cleveland Indians Batting Stats

2021 Cleveland Indians Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Jose Ramirez
3B
152 111 147 36 103 72 87 0.266
Amed Rosario
SS
141 77 155 11 57 31 120 0.282
Franmil Reyes
RF
115 57 106 30 85 43 149 0.254
Bo Bichette
SS
105 83 123 19 73 30 94 0.291
Marcus Semien
SS
105 79 116 25 66 42 104 0.275
Vladimir Guerrero Jr.
DH
104 82 123 34 85 59 75 0.322
Randal Grichuk
CF
103 45 97 19 68 16 86 0.254
Harold Ramirez
LF
99 33 91 7 41 14 56 0.268
Bradley Zimmer
CF
99 44 68 8 35 30 122 0.227
Cesar Hernandez
2B
96 60 87 18 47 38 90 0.231
Lourdes Gurriel Jr.
LF
93 39 89 11 42 17 73 0.264
Yu Chang
SS
89 32 54 9 39 11 69 0.228

St. Louis Cardinals Pitching Stats

2021 St. Louis Cardinals Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Adam Wainwright
SP
32 17 7 0 0 206.1 174 1.06 3.05
Alex Reyes
RP
70 10 8 29 3 72.1 95 1.35 3.24
Jack Flaherty
SP
17 9 2 0 0 78.1 85 1.06 3.22
Kwang Hyun Kim
SP
27 7 7 1 0 106.2 80 1.28 3.46
Giovanny Gallegos
RP
73 6 5 14 24 80.1 95 0.88 3.02
Ryan Helsley
RP
51 6 4 1 10 47.1 47 1.42 4.56
Matt Harvey
SP
27 6 14 0 0 123.1 93 1.52 6.28
Tanner Scott
RP
58 5 4 0 14 50.0 65 1.46 4.14
John Means
SP
20 5 6 0 0 114.1 104 1.00 3.46
J.A. Happ
SP
11 5 2 0 0 54.0 45 1.28 4.00
Genesis Cabrera
RP
71 4 5 0 28 70.0 77 1.26 3.73
Paul Fry
RP
52 4 5 2 11 47.1 60 1.52 6.08

Cleveland Indians Pitching Stats

2021 Cleveland Indians Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Aaron Civale
SP
21 12 5 0 0 124.1 99 1.12 3.84
Zach Plesac
SP
25 10 6 0 0 142.2 100 1.20 4.67
Lance Lynn
SP
19 10 3 0 0 108.2 122 1.05 2.07
Cal Quantrill
SP
40 8 3 0 1 149.2 121 1.18 2.89
Lucas Giolito
SP
22 8 8 0 0 129.0 145 1.16 3.98
Dylan Cease
SP
22 8 6 0 0 114.2 149 1.26 3.92
Carlos Rodon
SP
18 8 5 0 0 104.2 149 0.96 2.49
James Karinchak
RP
60 7 4 11 13 55.1 78 1.21 4.07
Dallas Keuchel
SP
21 7 4 0 0 113.2 71 1.35 4.51
Shane Bieber
SP
16 7 4 0 0 96.2 134 1.21 3.17
Bryan Shaw
RP
81 6 7 2 20 77.1 71 1.38 3.49
Liam Hendriks
RP
47 5 2 26 0 47.1 75 0.72 2.47

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