St. Louis Cardinals vs Cleveland Indians MLB Betting Lines

Odds Preview 2220

The Cardinals will play the Indians on Wednesday, July 28th, 2021 at 1:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers
  • Cardinals - K. Kim - L
  • Indians - Z. Plesac - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets
Underdog
Cleveland Indians
Cleveland Indians
Favorite
St. Louis Cardinals
St. Louis Cardinals
+100 Sb3gen1 -113 Sb3gen2
-105 Sb3gen3 -115 Sb3gen3
-107 Sb3gen2 -1008 Sb3gen1
Here are money lines for the outright winner. Favorite St. Louis Cardinals has a minus value. Lay $113 at Sb3gen2 to win $100. Underdog Cleveland Indians has a positive value. Risk $100 at Sb3gen1 to win $100.
Best Over and Under Total Lines
OverUnder
8.5o -120 Sb3gen1 9u -120 Sb3gen3
8.5o -120 Sb3gen2 8.5u +100 Sb3gen1
9o +100 Sb3gen3 8.5u +100 Sb3gen2
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 8.5 points laying $120 to win $100. Sb3gen3 has the best under line of 9 u -120.
Best Underdog and Favorite Run Line Bets
Underdog
St. Louis Cardinals
St. Louis Cardinals
Favorite
Cleveland Indians
Cleveland Indians
+1.5 -195 Sb3gen1 -1.5 +170 Sb3gen1
+1.5 -200 Sb3gen2 -1.5 +170 Sb3gen2
+1.5 -200 Sb3gen3 -1.5 +170 Sb3gen3
SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Sb3gen1 has the best favorite Cleveland Indians run line at -1.5 points. Sb3gen1 has the best underdog St. Louis Cardinals run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
OutcomeSB3Gen SB3Gen
St. Louis CardinalsSt. Louis Cardinals

Cached 2021-09-20 23:27:20
Cleveland Indians World Series Odds
OutcomeSB3Gen SB3Gen
Cleveland IndiansCleveland Indians

Cached 2021-09-20 23:27:20

Team Standings

Season Standings
Team W L Pct GB Home Away Strk L10
Cleveland IndiansSt. Louis Cardinals 79 69 0.534 17.0 79-69 42-33 W8 68-60
Cleveland IndiansCleveland Indians 73 74 0.497 22.5 73-74 36-36 W2 64-63

St. Louis Cardinals Batting Stats

2021 St. Louis Cardinals Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Tommy Edman
3B
146 83 157 10 49 35 88 0.267
Paul Goldschmidt
1B
145 90 161 26 87 63 125 0.290
Nolan Arenado
3B
144 74 141 32 99 44 88 0.255
Dylan Carlson
LF
136 72 130 15 59 52 141 0.258
Tyler O'Neill
LF
124 76 121 28 66 37 155 0.282
Matt Carpenter
2B
119 17 33 3 21 31 74 0.171
Yadier Molina
C
113 44 104 11 60 23 72 0.253
Edmundo Sosa
SS
105 37 73 6 27 15 52 0.277
Paul DeJong
SS
103 41 64 17 41 34 95 0.197
Harrison Bader
CF
89 32 79 12 43 26 72 0.248
Giovanny Gallegos
RP
65 0 0 0 0 0 0 0.000
Genesis Cabrera
RP
65 0 0 0 0 0 0 0.000

Cleveland Indians Batting Stats

2021 Cleveland Indians Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Jose Ramirez
3B
137 103 132 35 94 66 77 0.265
Amed Rosario
SS
133 70 144 10 51 27 114 0.279
Bo Bichette
SS
105 83 123 19 73 30 94 0.291
Marcus Semien
SS
105 79 116 25 66 42 104 0.275
Vladimir Guerrero Jr.
DH
104 82 123 34 85 59 75 0.322
Franmil Reyes
RF
103 55 98 30 80 39 135 0.259
Randal Grichuk
CF
103 45 97 19 68 16 86 0.254
Cesar Hernandez
2B
96 60 87 18 47 38 90 0.231
Lourdes Gurriel Jr.
LF
93 39 89 11 42 17 73 0.264
Harold Ramirez
LF
90 32 82 6 37 14 50 0.269
Bradley Zimmer
CF
86 38 60 7 30 30 107 0.231
Teoscar Hernandez
RF
86 48 99 17 66 23 92 0.294

St. Louis Cardinals Pitching Stats

2021 St. Louis Cardinals Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Adam Wainwright
SP
30 16 7 0 0 196.1 169 1.03 2.89
Alex Reyes
RP
66 9 8 29 2 68.2 87 1.33 2.88
Jack Flaherty
SP
14 9 2 0 0 76.0 81 1.03 3.08
Ryan Helsley
RP
51 6 4 1 10 47.1 47 1.42 4.56
Matt Harvey
SP
27 6 14 0 0 123.1 93 1.52 6.28
Kwang Hyun Kim
SP
24 6 7 1 0 101.2 78 1.27 3.63
Giovanny Gallegos
RP
67 5 5 10 24 74.1 88 0.85 3.27
Tanner Scott
RP
58 5 4 0 14 50.0 65 1.46 4.14
John Means
SP
20 5 6 0 0 114.1 104 1.00 3.46
Paul Fry
RP
52 4 5 2 11 47.1 60 1.52 6.08
John Gant
SP
25 4 6 0 1 76.1 56 1.57 3.42
Carlos Martinez
SP
16 4 9 0 0 82.1 57 1.37 6.23

Cleveland Indians Pitching Stats

2021 Cleveland Indians Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Aaron Civale
SP
18 11 4 0 0 111.1 89 1.09 3.40
Zach Plesac
SP
23 10 6 0 0 131.1 94 1.17 4.59
Lance Lynn
SP
19 10 3 0 0 108.2 122 1.05 2.07
Lucas Giolito
SP
22 8 8 0 0 129.0 145 1.16 3.98
Dylan Cease
SP
22 8 6 0 0 114.2 149 1.26 3.92
Carlos Rodon
SP
18 8 5 0 0 104.2 149 0.96 2.49
James Karinchak
RP
59 7 4 11 13 54.1 77 1.23 4.14
Dallas Keuchel
SP
21 7 4 0 0 113.2 71 1.35 4.51
Shane Bieber
SP
14 7 4 0 0 90.2 130 1.25 3.28
Bryan Shaw
RP
72 6 7 2 18 70.1 69 1.41 3.58
Cal Quantrill
SP
38 6 3 0 1 137.0 110 1.18 2.89
Liam Hendriks
RP
47 5 2 26 0 47.1 75 0.72 2.47

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