St. Louis Cardinals vs Pittsburgh Pirates Odds

The Cardinals will play the Pirates on Monday, April 27th, 2026. Your timezone's first pitch time is 6:40 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The St. Louis Cardinals have a 93.00 power ranking. The power ranking for the Pittsburgh Pirates is 95.33.
  • Visiting St. Louis Cardinals - The St. Louis Cardinals have a 7-4 record as a visiting team, ranking them 3rd Overall for visiting team wins.
  • Home Pittsburgh Pirates - The Pittsburgh Pirates have a 8-5 record as a home team. They rank 2nd for home team wins in the Overall standings.
  • Runs Scored - The St. Louis Cardinals currently stand 9th (111) Overall, with the Pittsburgh Pirates ranking 8th (114) for runs scored.
  • Runs Allowed - The St. Louis Cardinals are 5th (119) Overall for runs allowed. The Pittsburgh Pirates stand 17th (93) for runs allowed.
  • Team Streaks - The St. Louis Cardinals won their last game. Meanwhile, the Pittsburgh Pirates lost their last game.
  • Team Records - The St. Louis Cardinals have a 14-9 Overall record (1.5 GB National Central Division), with the Pittsburgh Pirates possessing a 13-10 Overall standing (2.5 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast, ye scallywags! The Cardinals be takin' on the Pirates in Pittsburgh on Monday...

Ye St. Louis swashbucklers be sittin' atop the division with a solid record...

But don't be lettin' yer guard down, for them Pirates be no pushovers...

Ye can place yer bets on this game at SportsBetting3.com, but beware...

Review the odds below before ye go throwin' away yer pieces of eight...

It be a clash of the titans, a battle for supremacy on the high seas...

So gather round, me hearties, and let's see which crew emerges victorious!

Best Cardinals at Pirates Odds


Best Moneyline Betting Odds
Underdog

St. Louis Cardinals
Favorite

Pittsburgh Pirates
The Pittsburgh Pirates are the -120 moneyline favorite. Risk $120 to win $100 on the Pittsburgh Pirates at BetMGM. The St. Louis Cardinals are the +100 underdog at BetMGM. Risk $100 to win $100 on the St. Louis Cardinals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8 runs. Risk $118 to win $100. BetMGM has the best under line of 8 runs. Risk $102 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

St. Louis Cardinals
Favorite

Pittsburgh Pirates
The Pittsburgh Pirates have a -1.5 +165 run line at BetMGM OH. They are the run line favorite in this matchup. The St. Louis Cardinals have a +1.5 -200 run line at BetMGM OH. The St. Louis Cardinals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the St. Louis Cardinals vs Pittsburgh Pirates MLB game on Monday, April 27th, 2026?

The Pittsburgh Pirates are the -120 moneyline favorite at BetMGM and the St. Louis Cardinals are the +100 moneyline underdog at BetMGM.

What is the over-under total line for the St. Louis Cardinals vs Pittsburgh Pirates MLB game on Monday, April 27th, 2026?

The best over line is 8 -118 runs at BetMGM, which means you risk $118 to win $100 betting the over. The best under line is 8 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.

What is the run line for the St. Louis Cardinals vs Pittsburgh Pirates MLB game on Monday, April 27th, 2026?

The Pittsburgh Pirates are -1.5 +165 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -200 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cardinals
Pirates
4/27/26 6:40pm EDT
+100-120
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • St. Louis Cardinals bettors risk $100 to win $100 at +100 odds. The implied probability for St. Louis Cardinals is 50%.
  • Pittsburgh Pirates bettors risk $100 to win $83.33 at -120 odds. The implied probability for Pittsburgh Pirates is 54.55%.

St. Louis Cardinals at Pittsburgh Pirates Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cardinals
Pirates
First Team to Score
4/27/26 6:40pm EDT
-150+115Bet
Cardinals
Pirates
Tie
1st Inning Winner
4/27/26 6:40pm EDT
+300+270-130Bet
Cardinals
Pirates
Tie
First 3 Innings Winner
4/27/26 6:40pm EDT
+154+125+300Bet
Cardinals
Pirates
To Extra Innings
4/27/26 6:40pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Cardinals
Pirates
1st Team to Score Will Win
4/27/26 6:40pm EDT
Yes -250No +190Bet
Pirates
Total Runs
STL at PIT
4/27/26 6:40pm EDT
3.5 o -1503.5 u +115Bet
Cardinals
Total Runs
STL at PIT
4/27/26 6:40pm EDT
3.5 o -1403.5 u +105Bet

St. Louis Cardinals & Pittsburgh Pirates Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
2026 St. Louis Cardinals World Series Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+15000
Bet
Pittsburgh Pirates World Series Odds
2026 Pittsburgh Pirates World Series Odds

Team
BetMGM Sports Betting BetMGM
Pirates
+3500
Bet

St. Louis Cardinals & Pittsburgh Pirates Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - St. Louis Cardinals, Pittsburgh Pirates
Team W L Pct GB Home Away RS RA Diff Strk L10
St. Louis Cardinals1490.609+2.07-57-4111119-8W16-4
Pittsburgh Pirates13100.565+3.08-55-511493+21L15-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the St. Louis Cardinals vs Pittsburgh Pirates MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Monday, April 27th, 2026 at 6:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Pittsburgh Pirates Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Pittsburgh Pirates Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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