The Nationals will play the Padres on Wednesday, June 25th, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the Washington Nationals possess a 88.00 SportsBetting3.com power ranking. The San Diego Padres now have a 95.00 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting Washington Nationals - The Washington Nationals head into this matchup with a 11-15 record as a visiting team. This standing ranks them 7th Overall for visiting team wins.
- Home San Diego Padres - The San Diego Padres will throw the first pitch possessing a 17-8 home team record. That puts them 4th for home team wins in the Overall MLB standings.
- Runs Scored - Washington Nationals batters have produced 225 runs, ranking them 15th Overall, with the San Diego Padres ranking 18th (217) for runs scored.
- Runs Allowed - Washington Nationals pitchers and fielders have allowed 273 runs, ranking them 6th Overall for runs allowed. Meanwhile, the San Diego Padres now rank 22nd Overall, allowing 199 runs.
- Team Streaks - The Washington Nationals lost their last game. Their opponent, the San Diego Padres have won their last 2 games.
- Team Records - Let's review each team's records. The Washington Nationals have a 24-29 Overall record (11.0 GB National East Division), with the San Diego Padres notching a 30-22 Overall standing (2.0 GB National West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Arrr, ye scurvy dogs, the Nationals be takin' on the Padres Wednesday...
San Diego be sittin' pretty with a better record, but beware...
Washington's been on a tear, winnin' 7 of their last 10...
Don't be countin' out the Nationals just yet, they be fightin' hard...
The Padres may be favored, but the Nationals be hungry for victory...
It be a clash of titans, with both teams lookin' to dominate...
Will the Padres defend their home turf, or will the Nationals plunder...
Tune in to this battle on Wednesday to see who comes out on top...
Check out this game's prop bets below, bet on MLB baseball at legal US sportsbooks...
(Just remember, anything can happen in the wild world of baseball)...
Nationals: 24-29, 0.453 overall win percentage, 7-3 last 10 games...
Padres: 30-22, 0.577 overall win percentage, 3-7 last 10 games...
Review each team's standing at the bottom of the page, may the best team win!
Best Nationals at Padres Odds
| Underdog Washington Nationals | Favorite San Diego Padres |
|---|---|
| Over | Under |
|---|---|
| Underdog Washington Nationals | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The San Diego Padres are the -150 moneyline favorite at BetMGM and the Washington Nationals are the +125 moneyline underdog at BetMGM.
The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The San Diego Padres are -1.5 +145 run line favorites at BetMGM, while the Washington Nationals are +1.5 -175 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Nationals
Padres
6/25/25 4:10pm EDT | +125-150 |
- Washington Nationals bettors risk $100 to win $125 at +125 odds. The implied probability for Washington Nationals is 44.44%.
- San Diego Padres bettors risk $100 to win $66.67 at -150 odds. The implied probability for San Diego Padres is 60%.
Washington Nationals at San Diego Padres Prop Bets
| BetMGM Bet |
|
|---|---|
Nationals
Padres
First Team to Score
6/25/25 4:10pm EDT | -140+110Bet |
Nationals
Padres
Tie
1st Inning Winner
6/25/25 4:10pm EDT | +333+333-160Bet |
Nationals
Padres
Tie
First 3 Innings Winner
6/25/25 4:10pm EDT | +154+145+240Bet |
Nationals
Padres
To Extra Innings
6/25/25 4:10pm EDT | Yes +700No -1100Bet |
| BetMGM | |
Nationals
Padres
1st Team to Score Will Win
6/25/25 4:10pm EDT | Yes -250No +190Bet |
Padres
Total Runs
WAS at SDG 6/25/25 4:10pm EDT | 3.5 o -1403.5 u +105Bet |
Nationals
Total Runs
WAS at SDG 6/25/25 4:10pm EDT | 3.5 o -1023.5 u -130Bet |
MacKenzie Gore
Strikeouts Thrown
WAS at SDG 6/25/25 4:10pm EDT | 5.5 o +1205.5 u -160Bet |
| BetMGM | |
Nick Pivetta
Strikeouts Thrown
WAS at SDG 6/25/25 4:10pm EDT | 5.5 o -1505.5 u +115Bet |
Washington Nationals & San Diego Padres Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Washington Nationals World Series Odds|
Team | BetMGM |
|---|---|
| Nationals | +50000 Bet |
|
Team | BetMGM |
|---|---|
| Padres | +3500 Bet |
Washington Nationals & San Diego Padres Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 30 | 22 | 0.577 | +4.0 | 17-8 | 13-14 | 217 | 199 | +18 | W2 | 3-7 |
| Washington Nationals | 24 | 29 | 0.453 | +10.5 | 13-14 | 11-15 | 225 | 273 | -48 | L1 | 7-3 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Washington Nationals vs San Diego Padres MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, June 25th, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Washington Nationals vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Washington Nationals vs San Diego Padres Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other June 25, 2025 MLB Games
- Arizona Diamondbacks vs Chicago White Sox - 6/25/25 2:10pm EDT
- Pittsburgh Pirates vs Milwaukee Brewers - 6/25/25 2:10pm EDT
- Boston Red Sox vs Los Angeles Angels - 6/25/25 4:07pm EDT
- Texas Rangers vs Baltimore Orioles - 6/25/25 6:35pm EDT
- Toronto Blue Jays vs Cleveland Guardians - 6/25/25 6:40pm EDT
- Oakland Athletics vs Detroit Tigers - 6/25/25 6:40pm EDT
- Atlanta Braves vs New York Mets - 6/25/25 7:10pm EDT
- New York Yankees vs Cincinnati Reds - 6/25/25 7:10pm EDT
- Tampa Bay Rays vs Kansas City Royals - 6/25/25 7:40pm EDT
- Seattle Mariners vs Minnesota Twins - 6/25/25 7:40pm EDT
- Chicago Cubs vs St. Louis Cardinals - 6/25/25 7:45pm EDT
- Philadelphia Phillies vs Houston Astros - 6/25/25 8:10pm EDT
- Los Angeles Dodgers vs Colorado Rockies - 6/25/25 8:40pm EDT
- Miami Marlins vs San Francisco Giants - 6/25/25 9:45pm EDT