DePaul vs Creighton Basketball Odds

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The Blue Demons will play the Bluejays on Wednesday, February 25th, 2026. Your timezone's tip off time is 9:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

Looking into the second half of the 2025-26 college basketball season, DePaul and Creighton are set to hit the hardwood on Wednesday, February 25th, 2026. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.

  • SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, DePaul currently has a 97.00 conference power ranking, while the SportsBetting3.com conference power ranking for Creighton is 96.67.
  • Away DePaul - DePaul starts this game with a 2-7 record as an away team, ranking them 5th in the Big East Conference for away team wins.
  • Home Creighton - Creighton meets DePaul boasting a 10-4 record as a home team. They currently rank 4th in the Big East Conference for home team wins.
  • Conference Win Percentage - DePaul currently ranks 5th (0.400) in the Big East Conference, with Creighton now standing 4th (0.500) for their conference win percentage in the 2025 Big East Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - DePaul has a 0.538 overall win percentage, with Creighton matching up with a 0.519 overall win percentage.
  • Team Records - DePaul currently possesses 14-12 regular season overall record. Meanwhile, Creighton has tallied a 14-13 standing as the 2025-26 college basketball season continues to unfold.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus, DePaul faces Creighton in a clash of magic on Wednesday.

DePaul and Creighton both seek conference tournament seeds in this crucial matchup. DePaul with a 6-9 record, Creighton with a 8-8 record so far.

Review the tables below to find the best point spread, total, and moneylines for this game. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below. Prepare for a bewitching battle under the bright lights of Creighton's court. Go forth, brave fans, and witness the wizardry of college basketball at its finest.

Best Blue Demons at Bluejays Odds


Best Point Spread Betting Odds
Underdog

DePaul		Favorite

Creighton
+3.5 -102 BetMGM
Bet
-3.5 -118 BetMGM
Bet
Creighton has a -3.5 -118 point spread at BetMGM OH. They are the point spread favorite in this matchup. DePaul has a +3.5 -102 point spread at BetMGM OH. DePaul is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
143.5 o -105 BetMGM
Bet
143.5 u -115 BetMGM
Bet
BetMGM has the best over line of 143.5 points. Risk $105 to win $100. BetMGM has the best under line of 143.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

DePaul		Favorite

Creighton
+155 BetMGM
Bet
-190 BetMGM
Bet
Creighton is the -190 moneyline favorite. Risk $190 to win $100 on Creighton at BetMGM. DePaul is the +155 underdog at BetMGM. Risk $100 to win $155 on DePaul. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the DePaul vs Creighton College Basketball game on Wednesday, February 25th, 2026?

Creighton is a -3.5 -118 point spread favorite at BetMGM, while DePaul is a +3.5 -102 point spread underdog at BetMGM.

What is the over-under total line for the DePaul vs Creighton College Basketball game on Wednesday, February 25th, 2026?

The best over line is 143.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 143.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the DePaul vs Creighton College Basketball game on Wednesday, February 25th, 2026?

Creighton is a -190 moneyline favorite at BetMGM and DePaul is a +155 moneyline underdog at BetMGM.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game		 BetMGM Sports Betting BetMGM
Bet
DePaul
Creighton
2/25/26 9:00pm EST
+3.5 -102-3.5 -118
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog DePaul - DePaul bettors risk $100 to win $98.04 at -102 odds.

A +3.5 DePaul underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite Creighton - Creighton bettors risk $100 to win $84.75 at -118 odds.

A -3.5 Creighton favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

DePaul at Creighton Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
DePaul
Creighton
First to 5 Points
2/25/26 9:00pm EST
-105-135Bet
DePaul
Creighton
First to 10 Points
2/25/26 9:00pm EST
+100-140Bet
DePaul
Creighton
First to 15 Points
2/25/26 9:00pm EST
+105-145Bet
DePaul
Creighton
Game to Overtime
2/25/26 9:00pm EST
Yes +800No -3000Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - DePaul, Creighton
Team W-L Win% Home Away Conf CGB Conf% Strk
DePaul16-160.50011-74-78-12+100.400L3
Creighton15-170.46910-64-89-11+90.450L1

DePaul & Creighton Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

DePaul Championship Odds

No NCAA Men's Basketball Tournament TM DePaul YR: futures available

Creighton Championship Odds

No NCAA Men's Basketball Tournament TM Creighton YR: futures available

DePaul & Creighton Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the DePaul vs Creighton College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, February 25th, 2026 at 9:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the DePaul vs Creighton Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the DePaul vs Creighton Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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