Duke vs Michigan State Basketball Odds

The Blue Devils will play the Spartans on Saturday, December 6th, 2025. Your timezone's tip off time is 12:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.

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Matchup Stats
Moneyline Mage
Best Odds
Interactive Odds Example
Prop Bets
Team Standings
Futures Odds
Team Pages
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Key Matchup Stats

The Duke and Michigan State basketball teams will play on Saturday, December 6th, 2025 as the 2025-26 college basketball season continues to roll along. Now that both teams have a few games under their belts, let’s size up this matchup by looking at some performance metrics and key stats.

SportsBetting3.com Power Rankings - Duke currently has a 100.00 conference power ranking so far in the 2025-26 season. The SportsBetting3.com conference power ranking for Michigan State is 100.00.
Away Duke - Duke heads into this game with a 1-0 record as an away team, ranking them 1st in the ACC Conference for away team wins.
Home Michigan State - Michigan State will host Duke sporting a 5-0 record as a home team. They currently rank 2nd in the Big Ten Conference for home team wins for the 2025-26 season.
Conference Win Percentage - Duke currently ranks 1st (0.000) in the ACC Conference, with Michigan State now standing 1st (1.000) for their conference win percentage in the 2025 Big Ten Conference for the 2025-26 college basketball season.
Overall Win Percentage - Duke has a 1.000 overall win percentage. Their opponent, Michigan State, has a 1.000 overall win percentage.
Team Records - Duke has a 9-0 regular season overall record. Michigan State has notched a 8-0 standing so far in the 2025-26 college basketball season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Hocus pocus! Duke 9-0 clashes with Michigan State 8-0 in epic battle Saturday!

Conference records crucial for tournament seeds. Duke 0-0 ACC, Michigan State 1-0 Big Ten.

Duke on fiery 9-game win streak, while Michigan State victorious in last 8 battles.

Our point spread, total, and moneyline tables show the best lines and odds for this matchup. Place a bet at BetMGM or BetRivers. Review each team’s futures odds and current standings below.

Best Blue Devils at Spartans Odds

**Best Point Spread Betting Odds**
Underdog Michigan State	Favorite Duke
+2 -113 BetRivers Bet	-2 -109 BetRivers Bet

Duke has a -2 -109 point spread at BetRivers PA. They are the point spread favorite in this matchup. Michigan State has a +2 -113 point spread at BetRivers PA. Michigan State is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
142 o -114 BetRivers Bet	142 u -109 BetRivers Bet

BetRivers has the best over line of 142 points. Risk $114 to win $100. BetRivers has the best under line of 142 points. Risk $109 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Michigan State	Favorite Duke
+106 BetRivers Bet	-132 BetRivers Bet

Duke is the -132 moneyline favorite. Risk $132 to win $100 on Duke at BetRivers. Michigan State is the +106 underdog at BetRivers. Risk $100 to win $106 on Michigan State. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Duke vs Michigan State College Basketball game on Saturday, December 6th, 2025?

Duke is a -2 -109 point spread favorite at BetRivers, while Michigan State is a +2 -113 point spread underdog at BetRivers.

What is the over-under total line for the Duke vs Michigan State College Basketball game on Saturday, December 6th, 2025?

The best over line is 142 -114 points at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 142 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.

What is the moneyline for the Duke vs Michigan State College Basketball game on Saturday, December 6th, 2025?

Duke is a -132 moneyline favorite at BetRivers and Michigan State is a +106 moneyline underdog at BetRivers.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained
Game	BetRivers Bet
Duke Michigan State 12/06/25 12:00pm EST	-2 -109 +2 -113

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Underdog Michigan State - Michigan State bettors risk $100 to win $88.5 at -113 odds.

A +2 Michigan State underdog bet wins if they lose by 1, tie, or win outright. The bet pushes if they lose by 2. Your bet loses if they lose by 3 or more.

Favorite Duke - Duke bettors risk $100 to win $91.74 at -109 odds.

A -2 Duke favorite bet wins if they win by 3 or more. The bet pushes if they win by 2. Your bet loses if they win by 1, tie, or lose outright.

Duke at Michigan State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
	BetRivers Bet
Duke Team Total Points DUKE at MSU 12/06/25 12:00pm EST	71.5 o -125 71.5 u -114 Bet
Michigan State Team Total Points DUKE at MSU 12/06/25 12:00pm EST	70.5 o -118 70.5 u -121 Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - Duke, Michigan State
Team	W-L	Win%	Home	Away	Conf	CGB	Conf%	Strk
ACC
#4 Duke	35-3	0.921	15-0	10-1	17-1	-	0.944	L1
Big Ten
#11 Michigan State	27-8	0.771	15-2	6-4	15-5	+4	0.750	L1

Duke & Michigan State Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Duke Championship Odds

2026-27 Duke NCAA Men's Basketball Tournament Odds
Team	BetRivers
Duke	+650 Bet

Michigan State Championship Odds

2026-27 Michigan State NCAA Men's Basketball Tournament Odds
Team	BetRivers
Michigan State	+1800 Bet

Duke & Michigan State Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Duke vs Michigan State College Basketball Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, December 6th, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Basketball page, look for the Duke vs Michigan State Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Duke vs Michigan State Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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