Louisville vs Clemson Basketball Odds

The Cardinals will play the Tigers on Saturday, February 28th, 2026. Your timezone's tip off time is 2:05 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.

STATE	Bonus
#1 BetMGM REVIEW	New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966

Matchup Stats
Moneyline Mage
Best Odds
Interactive Odds Example
Prop Bets
Team Standings
Futures Odds
Team Pages
Other Games Today

Key Matchup Stats

Looking into the second half of the 2025-26 college basketball season, Louisville and Clemson are set to hit the hardwood on Saturday, February 28th, 2026. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.

SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, Louisville currently has a 95.33 conference power ranking, while the SportsBetting3.com conference power ranking for Clemson is 95.33.
Away Louisville - Louisville starts this game with a 3-5 record as an away team, ranking them 3rd in the ACC Conference for away team wins.
Home Clemson - Clemson meets Louisville boasting a 11-2 record as a home team. They currently rank 5th in the ACC Conference for home team wins.
Conference Win Percentage - Louisville currently ranks 5th (0.615) in the ACC Conference, with Clemson now standing 4th (0.714) for their conference win percentage in the 2025 ACC Conference for the 2025-26 college basketball season.
Overall Win Percentage - Louisville has a 0.731 overall win percentage, with Clemson matching up with a 0.741 overall win percentage.
Team Records - Louisville currently possesses 19-7 regular season overall record. Meanwhile, Clemson has tallied a 20-7 standing as the 2025-26 college basketball season continues to unfold.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Hocus pocus! Louisville faces Clemson in a magical clash on Saturday.

Louisville and Clemson both have impressive records, with conference standings up for grabs. Louisville has a 19-7 overall standing, but Clemson is close behind at 20-7. Louisville's 8-5 ACC record is challenged by Clemson's 10-4 standing. Louisville has lost their last game, while Clemson has lost their last three. Review the tables below to find the best point spread, total, and moneylines for this game. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below. Let the basketball wizards battle it out on the court!

Best Cardinals at Tigers Odds

**Best Point Spread Betting Odds**
Underdog Clemson	Favorite Louisville
+1.5 -110 BetMGM Bet	-1.5 -110 BetMGM Bet

Louisville has a -1.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Clemson has a +1.5 -110 point spread at BetMGM OH. Clemson is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
146.5 o -110 BetMGM Bet	146.5 u -110 BetMGM Bet

BetMGM has the best over line of 146.5 points. Risk $110 to win $100. BetMGM has the best under line of 146.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Clemson	Favorite Louisville
+105 BetMGM Bet	-125 BetMGM Bet

Louisville is the -125 moneyline favorite. Risk $125 to win $100 on Louisville at BetMGM. Clemson is the +105 underdog at BetMGM. Risk $100 to win $105 on Clemson. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Louisville vs Clemson College Basketball game on Saturday, February 28th, 2026?

Louisville is a -1.5 -110 point spread favorite at BetMGM, while Clemson is a +1.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Louisville vs Clemson College Basketball game on Saturday, February 28th, 2026?

The best over line is 146.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 146.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Louisville vs Clemson College Basketball game on Saturday, February 28th, 2026?

Louisville is a -125 moneyline favorite at BetMGM and Clemson is a +105 moneyline underdog at BetMGM.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained
Game	BetMGM Bet
Louisville Clemson 2/28/26 2:05pm EST	-1.5 -110 +1.5 -110

Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Clemson - Clemson bettors risk $100 to win $90.91 at -110 odds.

A +1.5 Clemson underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.

Favorite Louisville - Louisville bettors risk $100 to win $90.91 at -110 odds.

A -1.5 Louisville favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.

Louisville at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
	BetMGM Bet
Louisville Clemson First to 5 Points 2/28/26 2:05pm EST	-120 -115 Bet
Louisville Clemson First to 10 Points 2/28/26 2:05pm EST	-125 -110 Bet
Louisville Clemson First to 15 Points 2/28/26 2:05pm EST	-125 -110 Bet
Louisville Clemson Game to Overtime 2/28/26 2:05pm EST	Yes +700 No -2000 Bet

Team Standings

2025-2026 College Basketball Regular Season Standings - Louisville, Clemson
Team	W-L	Win%	Home	Away	Conf	CGB	Conf%	Strk
Clemson	24-11	0.686	13-3	6-5	12-6	+5	0.667	L2
#23 Louisville	24-11	0.686	15-2	4-7	11-7	+6	0.611	L1

Louisville & Clemson Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Louisville Championship Odds

No NCAA Men's Basketball Tournament TM Louisville YR: futures available

Clemson Championship Odds

No NCAA Men's Basketball Tournament TM Clemson YR: futures available

Louisville & Clemson Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Louisville vs Clemson College Basketball Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 28th, 2026 at 2:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Basketball page, look for the Louisville vs Clemson Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Louisville vs Clemson Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other February 28, 2026 NCAABB Games

Odds Preview 29349

Table of Contents