Clemson vs South Carolina Football Odds

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The Tigers will play the Gamecocks on Saturday, November 29th, 2025. The matchup takes place at Williams-Brice Stadium. Watch this exciting Week 14 matchup at 12:00 pm EST. Check local listings for coverage on SEC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Clemson and South Carolina meeting at Williams-Brice Stadium for a key late-season matchup on Saturday, November 29th, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

  • SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Clemson has notched a 97.00 ACC Conference conference power ranking. On the other side of the gridiron, South Carolina has a 92.33 SEC Conference power ranking.
  • Away Clemson - Looking at Week 14, Clemson heads into this matchup with a 3-1 record as an away team. This ranks them 2nd in the ACC Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
  • Home South Carolina - Meanwhile, South Carolina has a 3-3 record as a home team for 2025. They currently rank 6th in the SEC Conference for home team wins. Let's see if they can add another win to their record when they battle Clemson on Saturday, November 29th, 2025.
  • Points Scored - Now late in the 2025 season, Clemson ranks 9th (316) in the ACC Conference, with South Carolina currently ranking 14th (258) for points scored in the SEC Conference.
  • Points Against - Clemson currently stands 13th (231) in the ACC Conference for points scored by opponents in the 2025 college football season. Their opponent, South Carolina, ranks 7th (237) in the SEC Conference for points against them as the 2025 college football season comes to a close.
  • Team Records - As we head into Week 14, Clemson has a 6-5 overall record for the 2025 regular season, with South Carolina possessing a 4-7 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Get ready for an epic showdown as Clemson faces South Carolina on Saturday!

The game is set to take place at Williams-Brice Stadium - it's going to be wild!

Clemson holds a Power Ranking of 97.00 compared to South Carolina's 92.33.

Clemson is currently 6-5 while South Carolina sits at 4-7. It's anyone's game! We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets and compare the best point spread, total, and moneylines from our partner sportsbooks below.

Best Tigers at Gamecocks Odds


Best Point Spread Betting Odds
Underdog

Clemson		Favorite

South Carolina
+2.5 -105 BetMGM
Bet
-2.5 -115 BetMGM
Bet
South Carolina has a -2.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Clemson has a +2.5 -105 point spread at BetMGM OH. Clemson is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
45.5 o -115 BetMGM
Bet
45.5 u -105 BetMGM
Bet
BetMGM has the best over line of 45.5 points. Risk $115 to win $100. BetMGM has the best under line of 45.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Clemson		Favorite

South Carolina
+125 BetMGM
Bet
-150 BetMGM
Bet
South Carolina is the -150 moneyline favorite. Risk $150 to win $100 on South Carolina at BetMGM. Clemson is the +125 underdog at BetMGM. Risk $100 to win $125 on Clemson. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

South Carolina is a -2.5 -115 point spread favorite at BetMGM, while Clemson is a +2.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

The best over line is 45.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 45.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

South Carolina is a -150 moneyline favorite at BetMGM and Clemson is a +125 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game		 BetMGM Sports Betting BetMGM
Bet
Clemson
South Carolina
11/29/25 12:00pm EST
+2.5 -105-2.5 -115
Bet $100 at BetMGM Ohio
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Underdog Clemson - Clemson bettors risk $100 to win $95.24 at -105 odds.

A +2.5 Clemson underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite South Carolina - South Carolina bettors risk $100 to win $86.96 at -115 odds.

A -2.5 South Carolina favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Clemson at South Carolina Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Clemson
South Carolina
No Touchdown
To Score 1st Touchdown
11/29/25 12:00pm EST
+110-160+10000Bet
Clemson
South Carolina
Game to Overtime
11/29/25 12:00pm EST
Yes +1050No -10000Bet
Clemson
South Carolina
Both Teams Score 10+
11/29/25 12:00pm EST
Yes -700No +450Bet
Clemson
South Carolina
Both Teams Score 20+
11/29/25 12:00pm EST
Yes +120No -155Bet
BetMGM Sports Betting BetMGM
Clemson
South Carolina
Both Teams Score 30+
11/29/25 12:00pm EST
Yes +825No -2000Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 14		Clemson vs South Carolina
Saturday, November 29th, 2025		CLEM 28, SC 14
Williams-Brice Stadium		Clemson by 14
2024
Week 14		South Carolina vs Clemson
Saturday, November 30th, 2024		SC 17, CLEM 14
Memorial Stadium (Clemson, SC)		South Carolina by 3
2023
Week 13		Clemson vs South Carolina
Saturday, November 25th, 2023		CLEM 16, SC 7
Williams-Brice Stadium		Clemson by 9
2022
Week 13		South Carolina vs Clemson
Saturday, November 26th, 2022		SC 31, CLEM 30
Memorial Stadium (Clemson, SC)		South Carolina by 1
2021
Week 13		Clemson vs South Carolina
Saturday, November 27th, 2021		CLEM 30, SC 0
Williams-Brice Stadium		Clemson by 30

Team Standings

2025-2026 College Football Regular Season Standings - Clemson, South Carolina
Team Conf Conf% W L PF PA Home Away Strk
ACC
Clemson4-40.500753442453-44-1W4
SEC
South Carolina1-70.125482722653-40-4L1

Clemson & South Carolina Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Clemson Championship Odds

No NCAA College Football Championship TM Clemson YR: futures available

South Carolina Championship Odds

No NCAA College Football Championship TM South Carolina YR: futures available

Clemson & South Carolina Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Clemson Games & Results
WeekMatchupDate & Result
Week 1LSU vs
Clemson		LSU 17, CLEM 10
Saturday, August 30th, 2025
Week 2Troy vs
Clemson		CLEM 27, TROY 16
Saturday, September 6th, 2025
Week 3Clemson vs
Georgia Tech		GT 24, CLEM 21
Saturday, September 13th, 2025
Week 4Syracuse vs
Clemson		SYR 34, CLEM 21
Saturday, September 20th, 2025
Week 6Clemson vs
North Carolina		CLEM 38, UNC 10
Saturday, October 4th, 2025
Week 7Clemson vs
Boston College		CLEM 41, BC 10
Saturday, October 11th, 2025
Week 8SMU vs
Clemson		SMU 35, CLEM 24
Saturday, October 18th, 2025
Week 10Duke vs
Clemson		DUKE 46, CLEM 45
Saturday, November 1st, 2025
Week 11Florida State vs
Clemson		CLEM 24, FSU 10
Saturday, November 8th, 2025
Week 12Clemson vs
Louisville		CLEM 20, LOU 19
Friday, November 14th, 2025
Week 13Furman vs
Clemson		CLEM 45, FUR 10
Saturday, November 22nd, 2025
Week 14Clemson vs
South Carolina		CLEM 28, SC 14
Saturday, November 29th, 2025
BowlsPenn State vs
Clemson
Bad Boy Mowers Pinstripe Bowl		Saturday, December 27th, 2025
12:00 pm EST


2025-26 South Carolina Games & Results
WeekMatchupDate & Result
Week 1Virginia Tech vs
South Carolina		SC 24, VT 11
Sunday, August 31st, 2025
Week 2South Carolina State vs
South Carolina		SC 38, SCST 10
Saturday, September 6th, 2025
Week 3Vanderbilt vs
South Carolina		VAN 31, SC 7
Saturday, September 13th, 2025
Week 4South Carolina vs
Missouri		MIZ 29, SC 20
Saturday, September 20th, 2025
Week 5Kentucky vs
South Carolina		SC 35, UK 13
Saturday, September 27th, 2025
Week 7South Carolina vs
LSU		LSU 20, SC 10
Saturday, October 11th, 2025
Week 8Oklahoma vs
South Carolina		OU 26, SC 7
Saturday, October 18th, 2025
Week 9Alabama vs
South Carolina		ALA 29, SC 22
Saturday, October 25th, 2025
Week 10South Carolina vs
Ole Miss		MISS 30, SC 14
Saturday, November 1st, 2025
Week 12South Carolina vs
Texas A&M		TA&M 31, SC 30
Saturday, November 15th, 2025
Week 13Coastal Carolina vs
South Carolina		SC 51, CCU 7
Saturday, November 22nd, 2025
Week 14Clemson vs
South Carolina		CLEM 28, SC 14
Saturday, November 29th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Clemson vs South Carolina College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 29th, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Clemson vs South Carolina Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Clemson vs South Carolina Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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