Clemson vs South Carolina Football Odds

The Tigers will play the Gamecocks on Saturday, November 29th, 2025. The matchup takes place at Williams-Brice Stadium. Watch this exciting Week 14 matchup at 12:00 pm EST. Check local listings for coverage on SEC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Matchup Stats
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Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Clemson and South Carolina meeting at Williams-Brice Stadium for a key late-season matchup on Saturday, November 29th, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Clemson has notched a 97.00 ACC Conference conference power ranking. On the other side of the gridiron, South Carolina has a 92.33 SEC Conference power ranking.
Away Clemson - Looking at Week 14, Clemson heads into this matchup with a 3-1 record as an away team. This ranks them 2nd in the ACC Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
Home South Carolina - Meanwhile, South Carolina has a 3-3 record as a home team for 2025. They currently rank 6th in the SEC Conference for home team wins. Let's see if they can add another win to their record when they battle Clemson on Saturday, November 29th, 2025.
Points Scored - Now late in the 2025 season, Clemson ranks 9th (316) in the ACC Conference, with South Carolina currently ranking 14th (258) for points scored in the SEC Conference.
Points Against - Clemson currently stands 13th (231) in the ACC Conference for points scored by opponents in the 2025 college football season. Their opponent, South Carolina, ranks 7th (237) in the SEC Conference for points against them as the 2025 college football season comes to a close.
Team Records - As we head into Week 14, Clemson has a 6-5 overall record for the 2025 regular season, with South Carolina possessing a 4-7 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Get ready for an epic showdown as Clemson faces South Carolina on Saturday!

The game is set to take place at Williams-Brice Stadium - it's going to be wild!

Clemson holds a Power Ranking of 97.00 compared to South Carolina's 92.33.

Clemson is currently 6-5 while South Carolina sits at 4-7. It's anyone's game! We recommend BetRivers or BetMGM for a bet on this game. Review this game's prop bets and compare the best point spread, total, and moneylines from our partner sportsbooks below.

Best Tigers at Gamecocks Odds

**Best Point Spread Betting Odds**
Underdog Clemson	Favorite South Carolina
+2.5 -105 BetMGM Bet	-2.5 -115 BetMGM Bet

South Carolina has a -2.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Clemson has a +2.5 -105 point spread at BetMGM OH. Clemson is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
45.5 o -115 BetMGM Bet	45.5 u -105 BetMGM Bet

BetMGM has the best over line of 45.5 points. Risk $115 to win $100. BetMGM has the best under line of 45.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Clemson	Favorite South Carolina
+125 BetMGM Bet	-150 BetMGM Bet

South Carolina is the -150 moneyline favorite. Risk $150 to win $100 on South Carolina at BetMGM. Clemson is the +125 underdog at BetMGM. Risk $100 to win $125 on Clemson. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

South Carolina is a -2.5 -115 point spread favorite at BetMGM, while Clemson is a +2.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

The best over line is 45.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 45.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Clemson vs South Carolina College Football game on Saturday, November 29th, 2025?

South Carolina is a -150 moneyline favorite at BetMGM and Clemson is a +125 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Clemson South Carolina 11/29/25 12:00pm EST	+2.5 -105 -2.5 -115

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Underdog Clemson - Clemson bettors risk $100 to win $95.24 at -105 odds.

A +2.5 Clemson underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite South Carolina - South Carolina bettors risk $100 to win $86.96 at -115 odds.

A -2.5 South Carolina favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Clemson at South Carolina Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Clemson South Carolina No Touchdown To Score 1st Touchdown 11/29/25 12:00pm EST	+110 -160 +10000 Bet
Clemson South Carolina Game to Overtime 11/29/25 12:00pm EST	Yes +1050 No -10000 Bet
Clemson South Carolina Both Teams Score 10+ 11/29/25 12:00pm EST	Yes -700 No +450 Bet
Clemson South Carolina Both Teams Score 20+ 11/29/25 12:00pm EST	Yes +120 No -155 Bet
	BetMGM
Clemson South Carolina Both Teams Score 30+ 11/29/25 12:00pm EST	Yes +825 No -2000 Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 14	Clemson vs South Carolina Saturday, November 29th, 2025	CLEM 28, SC 14 Williams-Brice Stadium	Clemson by 14
2024 Week 14	South Carolina vs Clemson Saturday, November 30th, 2024	SC 17, CLEM 14 Memorial Stadium (Clemson, SC)	South Carolina by 3
2023 Week 13	Clemson vs South Carolina Saturday, November 25th, 2023	CLEM 16, SC 7 Williams-Brice Stadium	Clemson by 9
2022 Week 13	South Carolina vs Clemson Saturday, November 26th, 2022	SC 31, CLEM 30 Memorial Stadium (Clemson, SC)	South Carolina by 1
2021 Week 13	Clemson vs South Carolina Saturday, November 27th, 2021	CLEM 30, SC 0 Williams-Brice Stadium	Clemson by 30

Team Standings

2025-2026 College Football Regular Season Standings - Clemson, South Carolina
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
ACC
Clemson	4-4	0.500	7	6	354	267	3-4	4-1	L1
SEC
South Carolina	1-7	0.125	4	8	272	265	3-4	0-4	L1

Clemson & South Carolina Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Clemson Championship Odds

No NCAA College Football Championship TM Clemson YR: futures available

South Carolina Championship Odds

No NCAA College Football Championship TM South Carolina YR: futures available

Clemson & South Carolina Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Clemson Games & Results
Week	Matchup	Date & Result
Week 1	LSU vs Clemson	LSU 17, CLEM 10 Saturday, August 30th, 2025
Week 2	Troy vs Clemson	CLEM 27, TROY 16 Saturday, September 6th, 2025
Week 3	Clemson vs Georgia Tech	GT 24, CLEM 21 Saturday, September 13th, 2025
Week 4	Syracuse vs Clemson	SYR 34, CLEM 21 Saturday, September 20th, 2025
Week 6	Clemson vs North Carolina	CLEM 38, UNC 10 Saturday, October 4th, 2025
Week 7	Clemson vs Boston College	CLEM 41, BC 10 Saturday, October 11th, 2025
Week 8	SMU vs Clemson	SMU 35, CLEM 24 Saturday, October 18th, 2025
Week 10	Duke vs Clemson	DUKE 46, CLEM 45 Saturday, November 1st, 2025
Week 11	Florida State vs Clemson	CLEM 24, FSU 10 Saturday, November 8th, 2025
Week 12	Clemson vs Louisville	CLEM 20, LOU 19 Friday, November 14th, 2025
Week 13	Furman vs Clemson	CLEM 45, FUR 10 Saturday, November 22nd, 2025
Week 14	Clemson vs South Carolina	CLEM 28, SC 14 Saturday, November 29th, 2025
Bowls	Penn State vs Clemson Bad Boy Mowers Pinstripe Bowl	PSU 22, CLEM 10 Saturday, December 27th, 2025

2025-26 South Carolina Games & Results
Week	Matchup	Date & Result
Week 1	Virginia Tech vs South Carolina	SC 24, VT 11 Sunday, August 31st, 2025
Week 2	South Carolina State vs South Carolina	SC 38, SCST 10 Saturday, September 6th, 2025
Week 3	Vanderbilt vs South Carolina	VAN 31, SC 7 Saturday, September 13th, 2025
Week 4	South Carolina vs Missouri	MIZ 29, SC 20 Saturday, September 20th, 2025
Week 5	Kentucky vs South Carolina	SC 35, UK 13 Saturday, September 27th, 2025
Week 7	South Carolina vs LSU	LSU 20, SC 10 Saturday, October 11th, 2025
Week 8	Oklahoma vs South Carolina	OU 26, SC 7 Saturday, October 18th, 2025
Week 9	Alabama vs South Carolina	ALA 29, SC 22 Saturday, October 25th, 2025
Week 10	South Carolina vs Ole Miss	MISS 30, SC 14 Saturday, November 1st, 2025
Week 12	South Carolina vs Texas A&M	TA&M 31, SC 30 Saturday, November 15th, 2025
Week 13	Coastal Carolina vs South Carolina	SC 51, CCU 7 Saturday, November 22nd, 2025
Week 14	Clemson vs South Carolina	CLEM 28, SC 14 Saturday, November 29th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Clemson vs South Carolina College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 29th, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Clemson vs South Carolina Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Clemson vs South Carolina Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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