Iowa State vs Clemson Football Odds

The Cyclones will play the Tigers on Wednesday, December 29th, 2021, in the annual Cheez-It Bowl event. The matchup takes place at Camping World Stadium. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets. Read the following to understand point spread betting.

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Total
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Moneyline
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Game

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9:17am EDT
TBD VA
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No VA Point Spread lines available for this game.

Iowa State at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
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Iowa State
Clemson
12/29/21 5:50pm EST
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Recent Meetings Since 2017

WeekGameResultMargin
2021
Bowls
Clemson vs Iowa State
Wednesday, December 29th, 2021
Cheez-It Bowl
CLEM 20, ISU 13
Camping World Stadium
Clemson by 7

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Iowa State Season Win Total
2022 College Football Iowa State Season Win Total
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Iowa State
2022 Season Win Total
Clemson Season Win Total
2022 College Football Clemson Season Win Total
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Clemson
2022 Season Win Total

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Iowa State Championship Odds
2024 Iowa State NCAA College Football Championship Odds

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Iowa State
Clemson Championship Odds
2024 Clemson NCAA College Football Championship Odds

Team
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Clemson

Team Standings

2021-2022 College Football Standings - Iowa State, Clemson
Team Conf Conf% W L PF PA Home Away Strk
ACC Atlantic
#14 Clemson6-20.7501033421936-03-2W6
Big 12
Iowa State5-40.556764072675-12-4L1

2021 Iowa State Games & Results

WeekMatchupDate & Time
Week 1Northern Iowa vs
Iowa State
ISU 16, UNI 10
Saturday, September 4th, 2021
Week 2Iowa vs
Iowa State
IOWA 27, ISU 17
Saturday, September 11th, 2021
Week 3Iowa State vs
UNLV
ISU 48, UNLV 3
Saturday, September 18th, 2021
Week 4Iowa State vs
Baylor
BAY 31, ISU 29
Saturday, September 25th, 2021
Week 5Kansas vs
Iowa State
ISU 59, KU 7
Saturday, October 2nd, 2021
Week 7Iowa State vs
Kansas State
ISU 33, KSU 20
Saturday, October 16th, 2021
Week 8Oklahoma State vs
Iowa State
ISU 24, OKST 21
Saturday, October 23rd, 2021
Week 9Iowa State vs
West Virginia
WVU 38, ISU 31
Saturday, October 30th, 2021
Week 10Texas vs
Iowa State
ISU 30, TEX 7
Saturday, November 6th, 2021
Week 11Iowa State vs
Texas Tech
TTU 41, ISU 38
Saturday, November 13th, 2021
Week 12Iowa State vs
Oklahoma
OU 28, ISU 21
Saturday, November 20th, 2021
Week 13TCU vs
Iowa State
ISU 48, TCU 14
Friday, November 26th, 2021
BowlsClemson vs
Iowa State
Cheez-It Bowl
CLEM 20, ISU 13
Wednesday, December 29th, 2021

2021 Clemson Games & Results

WeekMatchupDate & Time
Week 1Georgia vs
Clemson
UGA 10, CLEM 3
Saturday, September 4th, 2021
Week 2South Carolina State vs
Clemson
CLEM 49, SCST 3
Saturday, September 11th, 2021
Week 3Georgia Tech vs
Clemson
CLEM 14, GT 8
Saturday, September 18th, 2021
Week 4Clemson vs
NC State
NCST 27, CLEM 21 (2OT)
Saturday, September 25th, 2021
Week 5Boston College vs
Clemson
CLEM 19, BC 13
Saturday, October 2nd, 2021
Week 7Clemson vs
Syracuse
CLEM 17, SYR 14
Friday, October 15th, 2021
Week 8Clemson vs
Pittsburgh
PITT 27, CLEM 17
Saturday, October 23rd, 2021
Week 9Florida State vs
Clemson
CLEM 30, FSU 20
Saturday, October 30th, 2021
Week 10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
Week 11UConn vs
Clemson
CLEM 44, CONN 7
Saturday, November 13th, 2021
Week 12Wake Forest vs
Clemson
CLEM 48, WAKE 27
Saturday, November 20th, 2021
Week 13Clemson vs
South Carolina
CLEM 30, SC 0
Saturday, November 27th, 2021
BowlsClemson vs
Iowa State
Cheez-It Bowl
CLEM 20, ISU 13
Wednesday, December 29th, 2021

Other December 29, 2021 NCAAFB Games

Matchup
Virginia vs
SMU
Maryland vs
Virginia Tech
Oregon vs
Oklahoma
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