Iowa State vs Clemson Football Odds

The Cyclones will play the Tigers on Wednesday, December 29th, 2021, in the annual Cheez-It Bowl event. The matchup takes place at Camping World Stadium. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Best Cyclones at Tigers Odds


Best Point Spread Betting Odds
Underdog

Favorite

Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
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Best Moneyline Betting Odds
Underdog

Favorite

Moneyline odds are updating, please check back soon.

College Football Odds Example

College Football Odds and Outcomes Explained

Game

Bet
5:51am EDT
TBD VA,US
VA,US Odds Pending
No VA,US Point Spread lines available for this game.

Iowa State at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
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Iowa State
Clemson
12/29/21 5:50pm EST
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Recent Meetings Since 2017

Recent Meetings Since 2017
WeekGameResultMargin
2021
Bowls
Clemson vs Iowa State
Wednesday, December 29th, 2021
Cheez-It Bowl
CLEM 20, ISU 13
Camping World Stadium
Clemson by 7

Team Standings

2021-2022 College Football Regular Season Standings - Iowa State, Clemson
Team Conf Conf% W L PF PA Home Away Strk
ACC Atlantic
#14 Clemson6-20.7501033421936-03-2W6
Big 12
Iowa State5-40.556764072675-12-4L1

Iowa State & Clemson Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Iowa State Championship Odds
2024-25 Iowa State NCAA College Football Championship Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Iowa State
+40000
Bet
+20000
Bet
Clemson Championship Odds
2024-25 Clemson NCAA College Football Championship Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Clemson
+2000
Bet
+3000
Bet

Team Schedules & Results


2021-22 Iowa State Games & Results
WeekMatchupDate & Result
Week 1Northern Iowa vs
Iowa State
ISU 16, UNI 10
Saturday, September 4th, 2021
Week 2Iowa vs
Iowa State
IOWA 27, ISU 17
Saturday, September 11th, 2021
Week 3Iowa State vs
UNLV
ISU 48, UNLV 3
Saturday, September 18th, 2021
Week 4Iowa State vs
Baylor
BAY 31, ISU 29
Saturday, September 25th, 2021
Week 5Kansas vs
Iowa State
ISU 59, KU 7
Saturday, October 2nd, 2021
Week 7Iowa State vs
Kansas State
ISU 33, KSU 20
Saturday, October 16th, 2021
Week 8Oklahoma State vs
Iowa State
ISU 24, OKST 21
Saturday, October 23rd, 2021
Week 9Iowa State vs
West Virginia
WVU 38, ISU 31
Saturday, October 30th, 2021
Week 10Texas vs
Iowa State
ISU 30, TEX 7
Saturday, November 6th, 2021
Week 11Iowa State vs
Texas Tech
TTU 41, ISU 38
Saturday, November 13th, 2021
Week 12Iowa State vs
Oklahoma
OU 28, ISU 21
Saturday, November 20th, 2021
Week 13TCU vs
Iowa State
ISU 48, TCU 14
Friday, November 26th, 2021
BowlsClemson vs
Iowa State
Cheez-It Bowl
CLEM 20, ISU 13
Wednesday, December 29th, 2021


2021-22 Clemson Games & Results
WeekMatchupDate & Result
Week 1Georgia vs
Clemson
UGA 10, CLEM 3
Saturday, September 4th, 2021
Week 2South Carolina State vs
Clemson
CLEM 49, SCST 3
Saturday, September 11th, 2021
Week 3Georgia Tech vs
Clemson
CLEM 14, GT 8
Saturday, September 18th, 2021
Week 4Clemson vs
NC State
NCST 27, CLEM 21 (2OT)
Saturday, September 25th, 2021
Week 5Boston College vs
Clemson
CLEM 19, BC 13
Saturday, October 2nd, 2021
Week 7Clemson vs
Syracuse
CLEM 17, SYR 14
Friday, October 15th, 2021
Week 8Clemson vs
Pittsburgh
PITT 27, CLEM 17
Saturday, October 23rd, 2021
Week 9Florida State vs
Clemson
CLEM 30, FSU 20
Saturday, October 30th, 2021
Week 10Clemson vs
Louisville
CLEM 30, LOU 24
Saturday, November 6th, 2021
Week 11UConn vs
Clemson
CLEM 44, CONN 7
Saturday, November 13th, 2021
Week 12Wake Forest vs
Clemson
CLEM 48, WAKE 27
Saturday, November 20th, 2021
Week 13Clemson vs
South Carolina
CLEM 30, SC 0
Saturday, November 27th, 2021
BowlsClemson vs
Iowa State
Cheez-It Bowl
CLEM 20, ISU 13
Wednesday, December 29th, 2021

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Iowa State vs Clemson College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, December 29th, 2021 at 5:50 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Iowa State vs Clemson Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Iowa State vs Clemson Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other December 29, 2021 NCAAFB Games

Matchup
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SMU
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Oklahoma
Odds Preview 2444