Iowa State Cyclones vs Clemson Tigers Football Lines

Odds Preview 2444

The Cyclones will play the Tigers on Wednesday, December 29th, 2021.

Best Underdog and Favorite Spread Bets
Underdog

Iowa State
Favorite

Clemson
+2.5 -105 Sb3gen3 -1.5 -115 Sb3gen1
+2 -110 Sb3gen2 -2 -110 Sb3gen2
+1.5 -105 Sb3gen1 -2.5 -115 Sb3gen3
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Wednesday. Sb3gen1 has the best favorite Clemson spread at -1.5 points. Sb3gen3 has the best underdog Iowa State spread at +2.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
44.5o -110 Sb3gen3 45u -115 Sb3gen2
44.5o -115 Sb3gen1 44.5u -105 Sb3gen1
45o -105 Sb3gen2 44.5u -110 Sb3gen3
The over under line estimates the combined total of each team's final score. Sb3gen3 has the best over line of 44.5 points laying $110 to win $100. Sb3gen2 has the best under line of 45 u -115.
Best Money Line Bets
Underdog

Iowa State
Favorite

Clemson
+115 Sb3gen3 -125 Sb3gen1
+110 Sb3gen2 -130 Sb3gen2
+105 Sb3gen1 -135 Sb3gen3
Here are money lines for the outright winner. Favorite Clemson has a minus value. Lay $125 at Sb3gen1 to win $100. Underdog Iowa State has a positive value. Risk $100 at Sb3gen3 to win $115.

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

Iowa State Championship Odds
OutcomeSB3Gen SB3Gen

Cached 2022-01-28 01:09:17
Clemson Championship Odds
OutcomeSB3Gen SB3Gen

Cached 2022-01-28 01:09:17

2021 Iowa State Games & Results

WeekMatchupDate & Time
1 Northern Iowa vs
Iowa State
ISU 16, UNI 10
09/04/2021
2 Iowa vs
Iowa State
IOWA 27, ISU 17
09/11/2021
3 Iowa State vs
UNLV
ISU 48, UNLV 3
09/18/2021
4 Iowa State vs
Baylor
BAY 31, ISU 29
09/25/2021
5 Kansas vs
Iowa State
ISU 59, KU 7
10/02/2021
7 Iowa State vs
Kansas State
ISU 33, KSU 20
10/16/2021
8 Oklahoma State vs
Iowa State
ISU 24, OKST 21
10/23/2021
9 Iowa State vs
West Virginia
WVU 38, ISU 31
10/30/2021
10 Texas vs
Iowa State
ISU 30, TEX 7
11/06/2021
11 Iowa State vs
Texas Tech
TTU 41, ISU 38
11/13/2021
12 Iowa State vs
Oklahoma
OU 28, ISU 21
11/20/2021
13 TCU vs
Iowa State
ISU 48, TCU 14
11/26/2021

2021 Clemson Games & Results

WeekMatchupDate & Time
1 Georgia vs
Clemson
UGA 10, CLEM 3
09/04/2021
2 South Carolina State vs
Clemson
CLEM 49, SCST 3
09/11/2021
3 Georgia Tech vs
Clemson
CLEM 14, GT 8
09/18/2021
4 Clemson vs
NC State
NCST 27, CLEM 21 (2OT)
09/25/2021
5 Boston College vs
Clemson
CLEM 19, BC 13
10/02/2021
7 Clemson vs
Syracuse
CLEM 17, SYR 14
10/15/2021
8 Clemson vs
Pittsburgh
PITT 27, CLEM 17
10/23/2021
9 Florida State vs
Clemson
CLEM 30, FSU 20
10/30/2021
10 Clemson vs
Louisville
CLEM 30, LOU 24
11/06/2021
11 UConn vs
Clemson
CLEM 44, CONN 7
11/13/2021
12 Wake Forest vs
Clemson
CLEM 48, WAKE 27
11/20/2021
13 Clemson vs
South Carolina
CLEM 30, SC 0
11/27/2021

Other 2021 Week Matchups

Pending Schedule N/A (Week Undef)