The Dukes will play the Cardinals on Saturday, November 5th, 2022. The matchup takes place at Cardinal Stadium. Watch this exciting Week 10 matchup at 7:30 pm EDT. Check local listings for coverage on ESPNU.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Schedules & Results
- Other Games Today
Best Dukes at Cardinals Odds
| Underdog James Madison | Favorite Louisville |
|---|---|
| Over | Under |
|---|---|
| Underdog James Madison | Favorite Louisville |
|---|---|
Matchup Odds FAQs
Louisville is a -7 -105 point spread favorite at BetMGM, while James Madison is a +7 -113 point spread underdog at BetRivers.
The best over line is 52.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 53.5 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.
Louisville is a -245 moneyline favorite at BetRivers and James Madison is a +220 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
James Madison
Louisville
11/05/22 7:30pm EDT | +7 -115-7 -105 |
Underdog James Madison - James Madison bettors risk $100 to win $86.96 at -115 odds.
A +7 James Madison underdog bet wins if they lose by 6 or fewer, tie, or win outright. The bet pushes if they lose by 7. Your bet loses if they lose by 8 or more.
Favorite Louisville - Louisville bettors risk $100 to win $95.24 at -105 odds.
A -7 Louisville favorite bet wins if they win by 8 or more. The bet pushes if they win by 7. Your bet loses if they win by 6 or fewer, tie, or lose outright.
James Madison at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
James Madison
Louisville
11/05/22 7:30pm EDT | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2022 Week 10 | James Madison vs Louisville Saturday, November 5th, 2022 | LOU 34, JMU 10 Cardinal Stadium | Louisville by 24 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| ACC Atlantic | |||||||||
| Louisville | 4-4 | 0.500 | 8 | 5 | 350 | 249 | 5-1 | 2-4 | W1 |
| Sun Belt East | |||||||||
| James Madison | 6-2 | 0.750 | 8 | 3 | 407 | 230 | 5-1 | 3-2 | W3 |
James Madison & Louisville Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
James Madison Championship Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| James Madison | +40000 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Louisville | +10000 Bet | +10000 Bet |
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Middle Tennessee vs James Madison | JMU 44, MTSU 7 Saturday, September 3rd, 2022 |
| Week 2 | Norfolk State vs James Madison | JMU 63, NORF 7 Saturday, September 10th, 2022 |
| Week 4 | James Madison vs Appalachian State | JMU 32, APP 28 Saturday, September 24th, 2022 |
| Week 5 | Texas State vs James Madison | JMU 40, TXST 13 Saturday, October 1st, 2022 |
| Week 6 | James Madison vs Arkansas State | JMU 42, ARST 20 Saturday, October 8th, 2022 |
| Week 7 | James Madison vs Georgia Southern | GASO 45, JMU 38 Saturday, October 15th, 2022 |
| Week 8 | Marshall vs James Madison | MRSH 26, JMU 12 Saturday, October 22nd, 2022 |
| Week 10 | James Madison vs Louisville | LOU 34, JMU 10 Saturday, November 5th, 2022 |
| Week 11 | James Madison vs Old Dominion | JMU 37, ODU 3 Saturday, November 12th, 2022 |
| Week 12 | Georgia State vs James Madison | JMU 42, GAST 40 Saturday, November 19th, 2022 |
| Week 13 | Coastal Carolina vs James Madison | JMU 47, CCU 7 Saturday, November 26th, 2022 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Syracuse | SYR 31, LOU 7 Saturday, September 3rd, 2022 |
| Week 2 | Louisville vs UCF | LOU 20, UCF 14 Friday, September 9th, 2022 |
| Week 3 | Florida State vs Louisville | FSU 35, LOU 31 Friday, September 16th, 2022 |
| Week 4 | South Florida vs Louisville | LOU 41, USF 3 Saturday, September 24th, 2022 |
| Week 5 | Louisville vs Boston College | BC 34, LOU 33 Saturday, October 1st, 2022 |
| Week 6 | Louisville vs Virginia | LOU 34, UVA 17 Saturday, October 8th, 2022 |
| Week 8 | Pittsburgh vs Louisville | LOU 24, PITT 10 Saturday, October 22nd, 2022 |
| Week 9 | Wake Forest vs Louisville | LOU 48, WAKE 21 Saturday, October 29th, 2022 |
| Week 10 | James Madison vs Louisville | LOU 34, JMU 10 Saturday, November 5th, 2022 |
| Week 11 | Louisville vs Clemson | CLEM 31, LOU 16 Saturday, November 12th, 2022 |
| Week 12 | NC State vs Louisville | LOU 25, NCST 10 Saturday, November 19th, 2022 |
| Week 13 | Louisville vs Kentucky | UK 26, LOU 13 Saturday, November 26th, 2022 |
| Bowls | Cincinnati vs Louisville Wasabi Fenway Bowl | LOU 24, CIN 7 Saturday, December 17th, 2022 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the James Madison vs Louisville College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 5th, 2022 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the James Madison vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the James Madison vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.