USC Trojans vs Notre Dame Fighting Irish Football Lines

Odds Preview 1033

The Trojans will play the Fighting Irish on Saturday, October 23rd, 2021. The matchup takes place at Notre Dame Stadium. Watch this exciting week 8 matchup at 7:30 pm on NBC.

Best Underdog and Favorite Spread Bets
Underdog

USC
Favorite

Notre Dame
+7.5 -105 Sb3gen2 -7.5 +100 Sb3gen3
+7.5 -110 Sb3gen1 -7.5 -110 Sb3gen1
+7.5 -120 Sb3gen3 -7.5 -115 Sb3gen2
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Saturday. Sb3gen3 has the best favorite Notre Dame spread at -7.5 points. Sb3gen2 has the best underdog USC spread at +7.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
59o -110 Sb3gen2 59u -107 Sb3gen1
59o -110 Sb3gen3 59u -110 Sb3gen2
59o -113 Sb3gen1 59u -110 Sb3gen3
The over under line estimates the combined total of each team's final score. Sb3gen2 has the best over line of 59 points laying $110 to win $100. Sb3gen1 has the best under line of 59 u -107.
Best Money Line Bets
Underdog

USC
Favorite

Notre Dame
+240 Sb3gen2 -275 Sb3gen1
+230 Sb3gen1 -275 Sb3gen3
+225 Sb3gen3 -290 Sb3gen2
Here are money lines for the outright winner. Favorite Notre Dame has a minus value. Lay $275 at Sb3gen1 to win $100. Underdog USC has a positive value. Risk $100 at Sb3gen2 to win $240.

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

USC Championship Odds
OutcomeSB3Gen SB3Gen

Cached 2021-12-02 22:12:57
Notre Dame Championship Odds
OutcomeSB3Gen SB3Gen
Notre Dame

Cached 2021-12-02 22:12:57

2021 USC Games & Results

WeekMatchupDate & Time
1 San Jose State vs
USC
USC 30, SJSU 7
09/04/2021
2 Stanford vs
USC
STAN 42, USC 28
09/11/2021
3 USC vs
Washington State
USC 45, WSU 14
09/18/2021
4 Oregon State vs
USC
ORST 45, USC 27
09/25/2021
5 USC vs
Colorado
USC 37, COLO 14
10/02/2021
6 Utah vs
USC
UTAH 42, USC 26
10/09/2021
8 USC vs
Notre Dame
ND 31, USC 16
10/23/2021
9 Arizona vs
USC
USC 41, ARIZ 34
10/30/2021
10 USC vs
Arizona State
ASU 31, USC 16
11/06/2021
11 USC vs
California
11/13/2021
3:30PM
12 UCLA vs
USC
UCLA 62, USC 33
11/20/2021
13 BYU vs
USC
BYU 35, USC 31
11/27/2021
14 USC vs
California
12/04/2021
11:00PM

2021 Notre Dame Games & Results

WeekMatchupDate & Time
1 Notre Dame vs
Florida State
ND 41, FSU 38 (OT)
09/05/2021
2 Toledo vs
Notre Dame
ND 32, TOL 29
09/11/2021
3 Purdue vs
Notre Dame
ND 27, PUR 13
09/18/2021
4 Notre Dame vs
Wisconsin
ND 41, WISC 13
09/25/2021
5 Cincinnati vs
Notre Dame
CIN 24, ND 13
10/02/2021
6 Notre Dame vs
Virginia Tech
ND 32, VT 29
10/09/2021
8 USC vs
Notre Dame
ND 31, USC 16
10/23/2021
9 North Carolina vs
Notre Dame
ND 44, UNC 34
10/30/2021
10 Navy vs
Notre Dame
ND 34, NAVY 6
11/06/2021
11 Notre Dame vs
Virginia
ND 28, UVA 3
11/13/2021
12 Georgia Tech vs
Notre Dame
ND 55, GT 0
11/20/2021
13 Notre Dame vs
Stanford
ND 45, STAN 14
11/27/2021

Other 2021 Week 8 Matchups

MatchupDate & Time
Coastal Carolina vs
Appalachian State
APP 30, CCU 27
10/20/2021
Tulane vs
SMU
SMU 55, TULN 26
10/21/2021
Florida Atlantic vs
Charlotte
FAU 38, CLT 9
10/21/2021
Louisiana vs
Arkansas State
UL 28, ARST 27
10/21/2021
San Jose State vs
UNLV
SJSU 27, UNLV 20
10/21/2021
Middle Tennessee vs
UConn
MTSU 44, CONN 13
10/22/2021
Memphis vs
UCF
UCF 24, MEM 7
10/22/2021
Colorado State vs
Utah State
USU 26, CSU 24
10/22/2021
Washington vs
Arizona
WASH 21, ARIZ 16
10/22/2021
Cincinnati vs
Navy
CIN 27, NAVY 20
10/23/2021
Oklahoma vs
Kansas
OU 35, KU 23
10/23/2021
Northwestern vs
Michigan
MICH 33, NU 7
10/23/2021
Illinois vs
Penn State
ILL 20, PSU 18 (9OT)
10/23/2021
Wake Forest vs
Army
WAKE 70, ARMY 56
10/23/2021
Arkansas-Pine Bluff vs
Arkansas
ARK 45, UAPB 3
10/23/2021
UMass vs
Florida State
FSU 59, MASS 3
10/23/2021
Kansas State vs
Texas Tech
KSU 25, TTU 24
10/23/2021
Eastern Michigan vs
Bowling Green
EMU 55, BGSU 24
10/23/2021
Northern Illinois vs
Central Michigan
NIU 39, CMU 38
10/23/2021
Syracuse vs
Virginia Tech
SYR 41, VT 36
10/23/2021
Kent State vs
Ohio
KENT 34, OHIO 27
10/23/2021
Texas State vs
Georgia State
GAST 28, TXST 16
10/23/2021
Wisconsin vs
Purdue
WISC 30, PUR 13
10/23/2021
Oklahoma State vs
Iowa State
ISU 24, OKST 21
10/23/2021
LSU vs
Ole Miss
MISS 31, LSU 17
10/23/2021
Clemson vs
Pittsburgh
PITT 27, CLEM 17
10/23/2021
Rice vs
UAB
RICE 30, UAB 24
10/23/2021
Maryland vs
Minnesota
MINN 34, MD 16
10/23/2021
Miami (OH) vs
Ball State
M-OH 24, BALL 17
10/23/2021
Western Michigan vs
Toledo
TOL 34, WMU 15
10/23/2021
Buffalo vs
Akron
BUFF 45, AKR 10
10/23/2021
Colorado vs
California
CAL 26, COLO 3
10/23/2021
BYU vs
Washington State
BYU 21, WSU 19
10/23/2021
New Mexico vs
Wyoming
UNM 14, WYO 3
10/23/2021
Oregon vs
UCLA
ORE 34, UCLA 31
10/23/2021