USC Trojans vs Notre Dame Fighting Irish Football Lines

Odds Preview 1033

The Trojans will play the Fighting Irish on Saturday, October 23rd, 2021. The matchup takes place at Notre Dame Stadium. Watch this exciting week 8 matchup at 7:30 pm on NBC.

Best Underdog and Favorite Spread Bets

Underdog USC	Favorite Notre Dame
+7.5 -105 Sb3gen2	-7.5 +100 Sb3gen3
+7.5 -110 Sb3gen1	-7.5 -110 Sb3gen1
+7.5 -120 Sb3gen3	-7.5 -115 Sb3gen2

SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Saturday. Sb3gen3 has the best favorite Notre Dame spread at -7.5 points. Sb3gen2 has the best underdog USC spread at +7.5 points.

Review our point spread betting tutorial and video for more information.

Best Over and Under Total Lines

Over	Under
59o -110 Sb3gen2	59u -107 Sb3gen1
59o -110 Sb3gen3	59u -110 Sb3gen2
59o -113 Sb3gen1	59u -110 Sb3gen3

The over under line estimates the combined total of each team's final score. Sb3gen2 has the best over line of 59 points laying $110 to win $100. Sb3gen1 has the best under line of 59 u -107.

Best Money Line Bets

Underdog USC	Favorite Notre Dame
+240 Sb3gen2	-275 Sb3gen1
+230 Sb3gen1	-275 Sb3gen3
+225 Sb3gen3	-290 Sb3gen2

Here are money lines for the outright winner. Favorite Notre Dame has a minus value. Lay $275 at Sb3gen1 to win $100. Underdog USC has a positive value. Risk $100 at Sb3gen2 to win $240.

College Football Championship Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets here.

USC Championship Odds

Outcome	SB3Gen

Cached 2021-12-02 22:12:57
Notre Dame Championship Odds

Outcome	SB3Gen
Notre Dame	+2500

Cached 2021-12-02 22:12:57

2021 USC Games & Results

Week	Matchup	Date & Time
1	San Jose State vs USC	USC 30, SJSU 7 09/04/2021
2	Stanford vs USC	STAN 42, USC 28 09/11/2021
3	USC vs Washington State	USC 45, WSU 14 09/18/2021
4	Oregon State vs USC	ORST 45, USC 27 09/25/2021
5	USC vs Colorado	USC 37, COLO 14 10/02/2021
6	Utah vs USC	UTAH 42, USC 26 10/09/2021
8	USC vs Notre Dame	ND 31, USC 16 10/23/2021
9	Arizona vs USC	USC 41, ARIZ 34 10/30/2021
10	USC vs Arizona State	ASU 31, USC 16 11/06/2021
11	USC vs California	11/13/2021 3:30PM
12	UCLA vs USC	UCLA 62, USC 33 11/20/2021
13	BYU vs USC	BYU 35, USC 31 11/27/2021
14	USC vs California	12/04/2021 11:00PM

2021 Notre Dame Games & Results

Week	Matchup	Date & Time
1	Notre Dame vs Florida State	ND 41, FSU 38 (OT) 09/05/2021
2	Toledo vs Notre Dame	ND 32, TOL 29 09/11/2021
3	Purdue vs Notre Dame	ND 27, PUR 13 09/18/2021
4	Notre Dame vs Wisconsin	ND 41, WISC 13 09/25/2021
5	Cincinnati vs Notre Dame	CIN 24, ND 13 10/02/2021
6	Notre Dame vs Virginia Tech	ND 32, VT 29 10/09/2021
8	USC vs Notre Dame	ND 31, USC 16 10/23/2021
9	North Carolina vs Notre Dame	ND 44, UNC 34 10/30/2021
10	Navy vs Notre Dame	ND 34, NAVY 6 11/06/2021
11	Notre Dame vs Virginia	ND 28, UVA 3 11/13/2021
12	Georgia Tech vs Notre Dame	ND 55, GT 0 11/20/2021
13	Notre Dame vs Stanford	ND 45, STAN 14 11/27/2021

Other 2021 Week 8 Matchups

Matchup	Date & Time
Coastal Carolina vs Appalachian State	APP 30, CCU 27 10/20/2021
Tulane vs SMU	SMU 55, TULN 26 10/21/2021
Florida Atlantic vs Charlotte	FAU 38, CLT 9 10/21/2021
Louisiana vs Arkansas State	UL 28, ARST 27 10/21/2021
San Jose State vs UNLV	SJSU 27, UNLV 20 10/21/2021
Middle Tennessee vs UConn	MTSU 44, CONN 13 10/22/2021
Memphis vs UCF	UCF 24, MEM 7 10/22/2021
Colorado State vs Utah State	USU 26, CSU 24 10/22/2021
Washington vs Arizona	WASH 21, ARIZ 16 10/22/2021
Cincinnati vs Navy	CIN 27, NAVY 20 10/23/2021
Oklahoma vs Kansas	OU 35, KU 23 10/23/2021
Northwestern vs Michigan	MICH 33, NU 7 10/23/2021
Illinois vs Penn State	ILL 20, PSU 18 (9OT) 10/23/2021
Wake Forest vs Army	WAKE 70, ARMY 56 10/23/2021
Arkansas-Pine Bluff vs Arkansas	ARK 45, UAPB 3 10/23/2021
UMass vs Florida State	FSU 59, MASS 3 10/23/2021
Kansas State vs Texas Tech	KSU 25, TTU 24 10/23/2021
Eastern Michigan vs Bowling Green	EMU 55, BGSU 24 10/23/2021
Northern Illinois vs Central Michigan	NIU 39, CMU 38 10/23/2021
Syracuse vs Virginia Tech	SYR 41, VT 36 10/23/2021
Kent State vs Ohio	KENT 34, OHIO 27 10/23/2021
Texas State vs Georgia State	GAST 28, TXST 16 10/23/2021
Wisconsin vs Purdue	WISC 30, PUR 13 10/23/2021
Oklahoma State vs Iowa State	ISU 24, OKST 21 10/23/2021
LSU vs Ole Miss	MISS 31, LSU 17 10/23/2021
Clemson vs Pittsburgh	PITT 27, CLEM 17 10/23/2021
Rice vs UAB	RICE 30, UAB 24 10/23/2021
Maryland vs Minnesota	MINN 34, MD 16 10/23/2021
Miami (OH) vs Ball State	M-OH 24, BALL 17 10/23/2021
Western Michigan vs Toledo	TOL 34, WMU 15 10/23/2021
Buffalo vs Akron	BUFF 45, AKR 10 10/23/2021
Colorado vs California	CAL 26, COLO 3 10/23/2021
BYU vs Washington State	BYU 21, WSU 19 10/23/2021
New Mexico vs Wyoming	UNM 14, WYO 3 10/23/2021
Oregon vs UCLA	ORE 34, UCLA 31 10/23/2021