The Trojans will play the Boilermakers on Saturday, September 13th, 2025. The matchup takes place at Ross-Ade Stadium. Watch this exciting Week 3 matchup at 3:30 pm EDT. Check local listings for coverage on CBS, Paramount+.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season continues with USC matching up against Purdue at Ross-Ade Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - USC has a 99.67 conference power ranking for the 2025 season so far. The 2025 conference power ranking for Purdue is 97.00.
- Away USC - USC currently has a 0-0 record as an away team for the 2025 regular season, ranking them 2nd in the Big Ten Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home Purdue - So far, Purdue has a 2-0 record as a home team. They currently rank 1st in the Big Ten Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - USC ranks 1st (132) in the Big Ten Conference, with Purdue currently ranking 11th (65) for points scored in the 2025 Big Ten Conference.
- Points Against - USC stands 5th (33) in the Big Ten Conference for points scored by opponents in 2025. Purdue sits at 10th (17) in the 2025 Big Ten Conference for points against in the 2025 season.
- Team Records - USC has a 2-0 regular season overall record, with Purdue currently possessing a 2-0 regular season standing for the 2025 NCAAF season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for an epic showdown as USC faces Purdue at Ross-Ade Stadium this Saturday.
Purdue is looking to defend their home turf in this crucial early season matchup.
With both teams boasting a 2-0 record, this game promises to be a nail-biter.
For more excitement, head to SportsBetting3.com to review this game's prop bets and compare the odds below.
Best Trojans at Boilermakers Odds
| Underdog Purdue | Favorite USC |
|---|---|
| Over | Under |
|---|---|
| TBD | TBD |
|---|
Matchup Odds FAQs
USC is a -21.5 -110 point spread favorite at BetMGM, while Purdue is a +21.5 -110 point spread underdog at BetMGM.
The best over line is 58.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 58.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
USC
Purdue
9/13/25 3:30pm EDT | -21.5 -110+21.5 -110 |
Underdog Purdue - Purdue bettors risk $100 to win $90.91 at -110 odds.
A +21.5 Purdue underdog bet wins if they lose by 21 or fewer, tie, or win outright. Your bet loses if they lose by 22 or more.
Favorite USC - USC bettors risk $100 to win $90.91 at -110 odds.
A -21.5 USC favorite bet wins if they win by 22 or more. Your bet loses if they win by 21 or fewer, tie, or lose outright.
USC at Purdue Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
USC
Purdue
9/13/25 3:30pm EDT | Pending BetMGM |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| Purdue | 0-0 | 0.000 | 2 | 0 | 65 | 17 | 2-0 | 0-0 | W2 |
| USC | 0-0 | 0.000 | 2 | 0 | 132 | 33 | 2-0 | 0-0 | W2 |
USC & Purdue Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
USC Championship Odds|
Team | BetMGM |
|---|---|
| USC | +5000 Bet |
|
Team | BetMGM |
|---|---|
| Purdue | +100000 Bet |
USC & Purdue Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Missouri State vs USC | USC 73, MOST 13 Saturday, August 30th, 2025 |
| Week 2 | Georgia Southern vs USC | USC 59, GASO 20 Saturday, September 6th, 2025 |
| Week 3 | USC vs Purdue | Saturday, September 13th, 2025 3:30 pm EDT |
| Week 4 | Michigan State vs USC | Saturday, September 20th, 2025 12:00 am EDT |
| Week 5 | USC vs Illinois | Saturday, September 27th, 2025 12:00 am EDT |
| Week 7 | Michigan vs USC | Saturday, October 11th, 2025 12:00 am EDT |
| Week 8 | USC vs Notre Dame | Saturday, October 18th, 2025 7:30 pm EDT |
| Week 10 | USC vs Nebraska | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Northwestern vs USC | Friday, November 7th, 2025 9:00 pm EST |
| Week 12 | Iowa vs USC | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | USC vs Oregon | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | UCLA vs USC | Saturday, November 29th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Ball State vs Purdue | PUR 31, BALL 0 Saturday, August 30th, 2025 |
| Week 2 | Southern Illinois vs Purdue | PUR 34, SIU 17 Saturday, September 6th, 2025 |
| Week 3 | USC vs Purdue | Saturday, September 13th, 2025 3:30 pm EDT |
| Week 4 | Purdue vs Notre Dame | Saturday, September 20th, 2025 3:30 pm EDT |
| Week 6 | Illinois vs Purdue | Saturday, October 4th, 2025 12:00 am EDT |
| Week 7 | Purdue vs Minnesota | Saturday, October 11th, 2025 12:00 am EDT |
| Week 8 | Purdue vs Northwestern | Saturday, October 18th, 2025 12:00 am EDT |
| Week 9 | Rutgers vs Purdue | Saturday, October 25th, 2025 12:00 am EDT |
| Week 10 | Purdue vs Michigan | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | Ohio State vs Purdue | Saturday, November 8th, 2025 12:00 am EST |
| Week 12 | Purdue vs Washington | Saturday, November 15th, 2025 12:00 am EST |
| Week 14 | Indiana vs Purdue | Friday, November 28th, 2025 7:30 pm EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the USC vs Purdue College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 13th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the USC vs Purdue Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the USC vs Purdue Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 13, 2025 NCAAFB Games
- Oregon vs Northwestern - 9/13/25 12:00pm EDT
- Arkansas vs Ole Miss - 9/13/25 12:00pm EDT
- Memphis vs Troy - 9/13/25 12:00pm EDT
- Oklahoma vs Temple - 9/13/25 12:00pm EDT
- Buffalo vs Kent State - 9/13/25 12:00pm EDT
- Central Michigan vs Michigan - 9/13/25 12:00pm EDT
- Clemson vs Georgia Tech - 9/13/25 12:00pm EDT
- Wisconsin vs Alabama - 9/13/25 12:00pm EDT
- Vanderbilt vs South Carolina - 9/13/25 12:00pm EDT
- South Alabama vs Auburn - 9/13/25 12:45pm EDT
- UConn vs Delaware - 9/13/25 3:00pm EDT
- Pittsburgh vs West Virginia - 9/13/25 3:30pm EDT
- Washington State vs North Texas - 9/13/25 3:30pm EDT
- SMU vs Missouri State - 9/13/25 3:30pm EDT
- Oregon State vs Texas Tech - 9/13/25 3:30pm EDT
- Georgia vs Tennessee - 9/13/25 3:30pm EDT
- Iowa State vs Arkansas State - 9/13/25 4:00pm EDT
- Louisiana vs Missouri - 9/13/25 4:00pm EDT
- UTEP vs Texas - 9/13/25 4:15pm EDT
- South Florida vs Miami (FL) - 9/13/25 4:30pm EDT
- Middle Tennessee vs Nevada - 9/13/25 5:00pm EDT
- Liberty vs Bowling Green - 9/13/25 5:00pm EDT
- Florida Atlantic vs FIU - 9/13/25 6:00pm EDT
- Ohio vs Ohio State - 9/13/25 7:00pm EDT
- Western Michigan vs Illinois - 9/13/25 7:00pm EDT
- Jacksonville State vs Georgia Southern - 9/13/25 7:00pm EDT
- Appalachian State vs Southern Miss - 9/13/25 7:00pm EDT
- Old Dominion vs Virginia Tech - 9/13/25 7:00pm EDT
- Eastern Michigan vs Kentucky - 9/13/25 7:30pm EDT
- Florida vs LSU - 9/13/25 7:30pm EDT
- Texas A&M vs Notre Dame - 9/13/25 7:30pm EDT
- UMass vs Iowa - 9/13/25 7:30pm EDT
- East Carolina vs Coastal Carolina - 9/13/25 7:30pm EDT
- New Mexico State vs Louisiana Tech - 9/13/25 7:30pm EDT
- Utah vs Wyoming - 9/13/25 8:00pm EDT
- Navy vs Tulsa - 9/13/25 8:00pm EDT
- Duke vs Tulane - 9/13/25 8:00pm EDT
- Akron vs UAB - 9/13/25 8:30pm EDT
- Air Force vs Utah State - 9/13/25 9:45pm EDT
- Texas State vs Arizona State - 9/13/25 10:30pm EDT
- Minnesota vs California - 9/13/25 10:30pm EDT
- Boston College vs Stanford - 9/13/25 10:30pm EDT