Vanderbilt vs South Carolina Football Odds

The Commodores will play the Gamecocks on Saturday, September 13th, 2025. The matchup takes place at Williams-Brice Stadium. Watch this exciting Week 3 matchup at 7:45 pm EDT. Check local listings for coverage on SEC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

The 2025 college football season continues with Vanderbilt matching up against South Carolina at Williams-Brice Stadium. Let's review how each team is doing so far to better understand how this game will play out.

  • SportsBetting3.com Power Rankings - Vanderbilt has a 99.33 conference power ranking for the 2025 season so far. The 2025 conference power ranking for South Carolina is 97.33.
  • Away Vanderbilt - Vanderbilt currently has a 1-0 record as an away team for the 2025 regular season, ranking them 1st in the SEC Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
  • Home South Carolina - So far, South Carolina has a 1-0 record as a home team. They currently rank 2nd in the SEC Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
  • Points Scored - Vanderbilt ranks 6th (89) in the SEC Conference, with South Carolina currently ranking 11th (62) for points scored in the 2025 SEC Conference.
  • Points Against - Vanderbilt stands 7th (23) in the SEC Conference for points scored by opponents in 2025. South Carolina sits at 8th (21) in the 2025 SEC Conference for points against in the 2025 season.
  • Team Records - Vanderbilt has a 2-0 regular season overall record, with South Carolina currently possessing a 2-0 regular season standing for the 2025 NCAAF season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Ahoy, me hearties! This Saturday, September 13th, Vanderbilt be takin' on South Carolina at Williams-Brice Stadium.

The South Carolina will be lookin' to defend their home turf in this key early matchup.

Both teams be standin' at 2-0, so ye best be checkin' SportsBetting3.com to review this game's prop bets and compare the odds below. Arrr!

Best Commodores at Gamecocks Odds


Best Point Spread Betting Odds
Underdog

Vanderbilt
Favorite

South Carolina
South Carolina has a -3 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Vanderbilt has a +3 -110 point spread at BetMGM OH. Vanderbilt is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 48.5 points. Risk $110 to win $100. BetMGM has the best under line of 48.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Vanderbilt
Favorite

South Carolina
South Carolina is the -150 moneyline favorite. Risk $150 to win $100 on South Carolina at BetMGM. Vanderbilt is the +125 underdog at BetMGM. Risk $100 to win $125 on Vanderbilt. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Vanderbilt vs South Carolina College Football game on Saturday, September 13th, 2025?

South Carolina is a -3 -110 point spread favorite at BetMGM, while Vanderbilt is a +3 -110 point spread underdog at BetMGM.

What is the over-under total line for the Vanderbilt vs South Carolina College Football game on Saturday, September 13th, 2025?

The best over line is 48.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Vanderbilt vs South Carolina College Football game on Saturday, September 13th, 2025?

South Carolina is a -150 moneyline favorite at BetMGM and Vanderbilt is a +125 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Vanderbilt
South Carolina
9/13/25 7:45pm EDT
+3 -110-3 -110
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Vanderbilt - Vanderbilt bettors risk $100 to win $90.91 at -110 odds.

A +3 Vanderbilt underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.

Favorite South Carolina - South Carolina bettors risk $100 to win $90.91 at -110 odds.

A -3 South Carolina favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Vanderbilt at South Carolina Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Vanderbilt
South Carolina
No Touchdown
To Score 1st Touchdown
9/13/25 7:45pm EDT
+100-145+10000Bet
Vanderbilt
South Carolina
Game to Overtime
9/13/25 7:45pm EDT
Yes +950No -5000Bet
Vanderbilt
South Carolina
Both Teams Score 10+
9/13/25 7:45pm EDT
Yes -900No +525Bet
Vanderbilt
South Carolina
Both Teams Score 20+
9/13/25 7:45pm EDT
Yes -105No -120Bet
BetMGM Sports Betting BetMGM
Vanderbilt
South Carolina
Both Teams Score 30+
9/13/25 7:45pm EDT
Yes +550No -1000Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 11
South Carolina vs Vanderbilt
Saturday, November 9th, 2024
SC 28, VAN 7
FirstBank Stadium
South Carolina by 21
2023
Week 11
Vanderbilt vs South Carolina
Saturday, November 11th, 2023
SC 47, VAN 6
Williams-Brice Stadium
South Carolina by 41
2022
Week 10
South Carolina vs Vanderbilt
Saturday, November 5th, 2022
SC 38, VAN 27
FirstBank Stadium
South Carolina by 11
2021
Week 7
Vanderbilt vs South Carolina
Saturday, October 16th, 2021
SC 21, VAN 20
Williams-Brice Stadium
South Carolina by 1

Team Standings

2025-2026 College Football Regular Season Standings - Vanderbilt, South Carolina
Team Conf Conf% W L PF PA Home Away Strk
Vanderbilt1-01.00030120301-02-0W3
#11 South Carolina0-10.0002169521-10-0L1

Vanderbilt & South Carolina Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Vanderbilt Championship Odds
2025-26 Vanderbilt NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Vanderbilt
+50000
Bet
South Carolina Championship Odds
2025-26 South Carolina NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
South Carolina
+3000
Bet

Vanderbilt & South Carolina Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Vanderbilt Games & Results
WeekMatchupDate & Result
Week 1Charleston Southern vs
Vanderbilt
VAN 45, CHSO 3
Saturday, August 30th, 2025
Week 2Vanderbilt vs
Virginia Tech
VAN 44, VT 20
Saturday, September 6th, 2025
Week 3Vanderbilt vs
South Carolina
Saturday, September 13th, 2025
7:45 pm EDT
Week 4Georgia State vs
Vanderbilt
Saturday, September 20th, 2025
7:30 pm EDT
Week 5Utah State vs
Vanderbilt
Saturday, September 27th, 2025
12:45 pm EDT
Week 6Vanderbilt vs
Alabama
Saturday, October 4th, 2025
12:00 am EDT
Week 8LSU vs
Vanderbilt
Saturday, October 18th, 2025
12:00 am EDT
Week 9Missouri vs
Vanderbilt
Saturday, October 25th, 2025
12:00 am EDT
Week 10Vanderbilt vs
Texas
Saturday, November 1st, 2025
12:00 pm EDT
Week 11Auburn vs
Vanderbilt
Saturday, November 8th, 2025
12:00 am EST
Week 13Kentucky vs
Vanderbilt
Saturday, November 22nd, 2025
12:00 am EST
Week 14Vanderbilt vs
Tennessee
Saturday, November 29th, 2025
12:00 am EST


2025-26 South Carolina Games & Results
WeekMatchupDate & Result
Week 1Virginia Tech vs
South Carolina
SC 24, VT 11
Sunday, August 31st, 2025
Week 2South Carolina State vs
South Carolina
SC 38, SCST 10
Saturday, September 6th, 2025
Week 3Vanderbilt vs
South Carolina
Saturday, September 13th, 2025
7:45 pm EDT
Week 4South Carolina vs
Missouri
Saturday, September 20th, 2025
12:00 am EDT
Week 5Kentucky vs
South Carolina
Saturday, September 27th, 2025
12:00 am EDT
Week 7South Carolina vs
LSU
Saturday, October 11th, 2025
12:00 am EDT
Week 8Oklahoma vs
South Carolina
Saturday, October 18th, 2025
12:00 am EDT
Week 9Alabama vs
South Carolina
Saturday, October 25th, 2025
12:00 am EDT
Week 10South Carolina vs
Ole Miss
Saturday, November 1st, 2025
12:00 am EDT
Week 12South Carolina vs
Texas A&M
Saturday, November 15th, 2025
12:00 am EST
Week 13Coastal Carolina vs
South Carolina
Saturday, November 22nd, 2025
12:00 am EST
Week 14Clemson vs
South Carolina
Saturday, November 29th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Vanderbilt vs South Carolina College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 13th, 2025 at 7:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Vanderbilt vs South Carolina Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Vanderbilt vs South Carolina Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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