The Commodores will play the Gamecocks on Saturday, September 13th, 2025. The matchup takes place at Williams-Brice Stadium. Watch this exciting Week 3 matchup at 7:45 pm EDT. Check local listings for coverage on SEC Network.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
The 2025 college football season continues with Vanderbilt matching up against South Carolina at Williams-Brice Stadium. Let's review how each team is doing so far to better understand how this game will play out.
- SportsBetting3.com Power Rankings - Vanderbilt has a 99.33 conference power ranking for the 2025 season so far. The 2025 conference power ranking for South Carolina is 97.33.
- Away Vanderbilt - Vanderbilt currently has a 1-0 record as an away team for the 2025 regular season, ranking them 1st in the SEC Conference for away team wins. Not much can be concluded from this stat just yet, so stay tuned.
- Home South Carolina - So far, South Carolina has a 1-0 record as a home team. They currently rank 2nd in the SEC Conference for home team wins in 2025. Keep tabs on this figure, as it will change in the coming weeks.
- Points Scored - Vanderbilt ranks 6th (89) in the SEC Conference, with South Carolina currently ranking 11th (62) for points scored in the 2025 SEC Conference.
- Points Against - Vanderbilt stands 7th (23) in the SEC Conference for points scored by opponents in 2025. South Carolina sits at 8th (21) in the 2025 SEC Conference for points against in the 2025 season.
- Team Records - Vanderbilt has a 2-0 regular season overall record, with South Carolina currently possessing a 2-0 regular season standing for the 2025 NCAAF season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Ahoy, me hearties! This Saturday, September 13th, Vanderbilt be takin' on South Carolina at Williams-Brice Stadium.
The South Carolina will be lookin' to defend their home turf in this key early matchup.
Both teams be standin' at 2-0, so ye best be checkin' SportsBetting3.com to review this game's prop bets and compare the odds below. Arrr!
Best Commodores at Gamecocks Odds
| Underdog Vanderbilt | Favorite South Carolina |
|---|---|
| Over | Under |
|---|---|
| Underdog Vanderbilt | Favorite South Carolina |
|---|---|
Matchup Odds FAQs
South Carolina is a -3 -110 point spread favorite at BetMGM, while Vanderbilt is a +3 -110 point spread underdog at BetMGM.
The best over line is 48.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
South Carolina is a -150 moneyline favorite at BetMGM and Vanderbilt is a +125 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
Vanderbilt
South Carolina
9/13/25 7:45pm EDT | +3 -110-3 -110 |
Underdog Vanderbilt - Vanderbilt bettors risk $100 to win $90.91 at -110 odds.
A +3 Vanderbilt underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.
Favorite South Carolina - South Carolina bettors risk $100 to win $90.91 at -110 odds.
A -3 South Carolina favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.
Vanderbilt at South Carolina Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Vanderbilt
South Carolina
No Touchdown
To Score 1st Touchdown
9/13/25 7:45pm EDT | +100-145+10000Bet |
Vanderbilt
South Carolina
Game to Overtime
9/13/25 7:45pm EDT | Yes +950No -5000Bet |
Vanderbilt
South Carolina
Both Teams Score 10+
9/13/25 7:45pm EDT | Yes -900No +525Bet |
Vanderbilt
South Carolina
Both Teams Score 20+
9/13/25 7:45pm EDT | Yes -105No -120Bet |
| BetMGM | |
Vanderbilt
South Carolina
Both Teams Score 30+
9/13/25 7:45pm EDT | Yes +550No -1000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 3 | Vanderbilt vs South Carolina Saturday, September 13th, 2025 | VAN 31, SC 7 Williams-Brice Stadium | Vanderbilt by 24 |
| 2024 Week 11 | South Carolina vs Vanderbilt Saturday, November 9th, 2024 | SC 28, VAN 7 FirstBank Stadium | South Carolina by 21 |
| 2023 Week 11 | Vanderbilt vs South Carolina Saturday, November 11th, 2023 | SC 47, VAN 6 Williams-Brice Stadium | South Carolina by 41 |
| 2022 Week 10 | South Carolina vs Vanderbilt Saturday, November 5th, 2022 | SC 38, VAN 27 FirstBank Stadium | South Carolina by 11 |
| 2021 Week 7 | Vanderbilt vs South Carolina Saturday, October 16th, 2021 | SC 21, VAN 20 Williams-Brice Stadium | South Carolina by 1 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #20 Vanderbilt | 1-1 | 0.500 | 5 | 1 | 259 | 116 | 3-0 | 2-1 | L1 |
| South Carolina | 1-3 | 0.250 | 3 | 3 | 134 | 114 | 2-1 | 0-2 | L1 |
Vanderbilt & South Carolina Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
Vanderbilt Championship Odds|
Team | BetMGM |
|---|---|
| Vanderbilt | +8000 Bet |
|
Team | BetMGM |
|---|---|
| South Carolina | +50000 Bet |
Vanderbilt & South Carolina Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Charleston Southern vs Vanderbilt | VAN 45, CHSO 3 Saturday, August 30th, 2025 |
| Week 2 | Vanderbilt vs Virginia Tech | VAN 44, VT 20 Saturday, September 6th, 2025 |
| Week 3 | Vanderbilt vs South Carolina | VAN 31, SC 7 Saturday, September 13th, 2025 |
| Week 4 | Georgia State vs Vanderbilt | VAN 70, GAST 21 Saturday, September 20th, 2025 |
| Week 5 | Utah State vs Vanderbilt | VAN 55, USU 35 Saturday, September 27th, 2025 |
| Week 6 | Vanderbilt vs Alabama | ALA 30, VAN 14 Saturday, October 4th, 2025 |
| Week 8 | LSU vs Vanderbilt | Saturday, October 18th, 2025 12:00 pm EDT |
| Week 9 | Missouri vs Vanderbilt | Saturday, October 25th, 2025 12:00 am EDT |
| Week 10 | Vanderbilt vs Texas | Saturday, November 1st, 2025 12:00 pm EDT |
| Week 11 | Auburn vs Vanderbilt | Saturday, November 8th, 2025 12:00 am EST |
| Week 13 | Kentucky vs Vanderbilt | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Vanderbilt vs Tennessee | Saturday, November 29th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Virginia Tech vs South Carolina | SC 24, VT 11 Sunday, August 31st, 2025 |
| Week 2 | South Carolina State vs South Carolina | SC 38, SCST 10 Saturday, September 6th, 2025 |
| Week 3 | Vanderbilt vs South Carolina | VAN 31, SC 7 Saturday, September 13th, 2025 |
| Week 4 | South Carolina vs Missouri | MIZ 29, SC 20 Saturday, September 20th, 2025 |
| Week 5 | Kentucky vs South Carolina | SC 35, UK 13 Saturday, September 27th, 2025 |
| Week 7 | South Carolina vs LSU | LSU 20, SC 10 Saturday, October 11th, 2025 |
| Week 8 | Oklahoma vs South Carolina | Saturday, October 18th, 2025 12:45 pm EDT |
| Week 9 | Alabama vs South Carolina | Saturday, October 25th, 2025 3:30 pm EDT |
| Week 10 | South Carolina vs Ole Miss | Saturday, November 1st, 2025 12:00 am EDT |
| Week 12 | South Carolina vs Texas A&M | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Coastal Carolina vs South Carolina | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | Clemson vs South Carolina | Saturday, November 29th, 2025 12:00 pm EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Vanderbilt vs South Carolina College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 13th, 2025 at 7:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the Vanderbilt vs South Carolina Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Vanderbilt vs South Carolina Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 13, 2025 NCAAFB Games
- Memphis vs Troy
- Oklahoma vs Temple
- Buffalo vs Kent State
- Central Michigan vs Michigan
- Oregon vs Northwestern
- Clemson vs Georgia Tech
- Wisconsin vs Alabama
- William & Mary vs Virginia
- Towson vs Maryland
- South Alabama vs Auburn
- Louisiana vs Missouri
- Northern Colorado vs South Dakota
- Rhode Island vs Holy Cross
- New Hampshire vs Ball State
- Elon vs Western Carolina
- Illinois State vs Eastern Illinois
- North Dakota vs Montana
- San Diego vs Montana State
- UConn vs Delaware
- Fordham vs Stony Brook
- Youngstown State vs Michigan State
- VMI vs Bucknell
- Northwestern State vs Cincinnati
- Villanova vs Penn State
- Southeast Missouri State vs North Dakota State
- Richmond vs North Carolina
- Incarnate Word vs UTSA
- Furman vs Campbell
- Morgan State vs Toledo
- Washington State vs North Texas
- Pittsburgh vs West Virginia
- Georgia vs Tennessee
- Oregon State vs Texas Tech
- SMU vs Missouri State
- Iowa State vs Arkansas State
- Utah Tech vs Idaho
- Lindenwood vs Charleston Southern
- UTEP vs Texas
- South Florida vs Miami (FL)
- Alabama A&M vs Tennessee State
- Eastern Washington vs Northern Iowa
- Liberty vs Bowling Green
- Middle Tennessee vs Nevada
- USC vs Purdue
- Alcorn State vs Mississippi State
- East Tennessee State vs West Georgia
- Eastern Kentucky vs Marshall
- Merrimack College vs Kennesaw State
- Bethune-Cookman vs South Carolina State
- Wofford vs Mercer
- Stonehill vs Maine
- Stetson vs Chattanooga
- Valparaiso vs Western Illinois
- Southern Illinois vs UT-Martin
- Prairie View A&M vs Rice
- New Haven vs Albany
- The Citadel vs Gardner-Webb
- Murray State vs Georgia State
- Morehead State vs Austin Peay
- Miss Valley State vs Southeastern Louisiana
- Lamar vs Texas Southern
- Hampton vs North Carolina A&T
- Drake vs South Dakota State
- Weber State vs McNeese State
- Jacksonville State vs Georgia Southern
- Tarleton vs Central Arkansas
- Old Dominion vs Virginia Tech
- Ohio vs Ohio State
- Western Michigan vs Illinois
- Arkansas vs Ole Miss
- Appalachian State vs Southern Miss
- New Mexico State vs Louisiana Tech
- UMass vs Iowa
- East Carolina vs Coastal Carolina
- Florida vs LSU
- Texas A&M vs Notre Dame
- Eastern Michigan vs Kentucky
- Abilene Christian vs TCU
- Navy vs Tulsa
- Utah vs Wyoming
- Duke vs Tulane
- Florida Atlantic vs FIU
- Northern Arizona vs Southern Utah
- Akron vs UAB
- Mercyhurst vs Sacramento State
- Air Force vs Utah State
- Southern vs Fresno State
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- Texas State vs Arizona State
- Minnesota vs California