Buffalo Bills vs Los Angeles Rams Odds

The Bills will play the Rams on Thursday, September 8th, 2022. The matchup takes place at SoFi Stadium. Watch this exciting Week 1 matchup at 8:20 pm EDT. Check local listings for coverage on NBC.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props. Read the following to understand point spread betting.

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Point Spread
Underdog

Los Angeles Rams
Favorite

Buffalo Bills
+2.5 -112 BetRivers-2.5 -109 BetRivers
SportsBetting3.com has analyzed the latest lines. Review our "Point Spread" table above to smash the books. BetRivers VA has the best favorite Buffalo Bills point spread at -2.5 points. BetRivers has the best underdog Los Angeles Rams point spread at +2.5 points. Review our point spread betting tutorial and video for more information.

Total
OverUnder
51.5o -113 BetRivers51.5u -108 BetRivers
The over under line estimates the combined total of each team's final score. BetRivers has the best over line of 51.5 points laying $113 to win $100. BetRivers has the best under line of 51.5 points.

Moneyline
Underdog

Los Angeles Rams
Favorite

Buffalo Bills
+117 BetRivers-132 BetRivers
Here are money lines for the outright winner. Favorite Buffalo Bills has a minus value. Lay $132 to win $100 at BetRivers. Underdog Los Angeles Rams has a positive value. Risk $100 at BetRivers to win $117.

SportsBetting3.com NFL Odds Example

NFL Odds and Outcomes Explained

Game
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Bills
Rams
9/08/22 8:20pm EDT

Underdog Los Angeles Rams - Los Angeles Rams bettors risk $100 to win $89.29 at -112 odds.

A +2.5 Los Angeles Rams underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $91.74 at -109 odds.

A -2.5 Buffalo Bills favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Buffalo Bills at Los Angeles Rams Prop Bets

NFL Prop Bets
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Bills
Rams
9/08/22 8:20pm EDT - First Team To Score
Bills
Rams
Tie
9/08/22 8:20pm EDT - First to 15 Points
Bills
Rams
Tie
9/08/22 8:20pm EDT - First to 20 Points

Recent Meetings Since 2018

WeekGameResultMargin
2022
Week 1
Bills vs Rams
Thursday, September 8th, 2022
BUF 31, LAR 10
SoFi Stadium
Bills by 21
2020
Week 3
Rams vs Bills
Sunday, September 27th, 2020
BUF 35, LAR 32
Highmark Stadium
Bills by 3

Regular Season Team Standings

2022 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
Buffalo Bills
1-1-0 0-1-0 2 1 0 0.667 1-0-0 1-1-0 2-1-0
Los Angeles Rams
2-0-0 1-0-0 2 1 0 0.667 1-1-0 1-0-0 2-1-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 77 46
Total Offensive Yards 1324 642
Total Rushing Yards 337 173
Total Passing Yards 1014 469
Sacks 7 11
Field Goals 4 / 5 1 / 1
Touchdowns 11 5
Turnover Ratio 2

Los Angeles Rams Team Stats
Stat Los Angeles Rams Opponents
Total 1st Downs 58 63
Total Offensive Yards 919 1039
Total Rushing Yards 217 281
Total Passing Yards 761 758
Sacks 9 7
Field Goals 4 / 4 6 / 7
Touchdowns 7 6
Turnover Ratio 0

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Buffalo Bills Season Win Total
2022 NFL Buffalo Bills Season Win Total
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Buffalo Bills
2022 Season Win Total
Los Angeles Rams Season Win Total
2022 NFL Los Angeles Rams Season Win Total
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Los Angeles Rams
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds
2023 Buffalo Bills Super Bowl Winner Odds

Team
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Buffalo Bills
Los Angeles Rams Futures Odds
2023 Los Angeles Rams Super Bowl Winner Odds

Team
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Los Angeles Rams

2022 Buffalo Bills Games & Results

WeekMatchupDate & Time
Preseason 1Colts vs
Bills
BUF 27, IND 24
Saturday, August 13th, 2022
Preseason 2Broncos vs
Bills
BUF 42, DEN 15
Saturday, August 20th, 2022
Preseason 3Bills vs
Panthers
CAR 21, BUF 0
Friday, August 26th, 2022
Week 1Bills vs
Rams
BUF 31, LAR 10
Thursday, September 8th, 2022
Week 2Titans vs
Bills
BUF 41, TEN 7
Monday, September 19th, 2022
Week 3Bills vs
Dolphins
MIA 21, BUF 19
Sunday, September 25th, 2022
Week 4Bills vs
Ravens
Sunday, October 2nd, 2022
1:00 pm EDT
Week 5Steelers vs
Bills
Sunday, October 9th, 2022
1:00 pm EDT
Week 6Bills vs
Chiefs
Sunday, October 16th, 2022
4:25 pm EDT
Week 7Bills
Bye Week
Week 8Packers vs
Bills
Sunday, October 30th, 2022
8:20 pm EDT
Week 9Bills vs
Jets
Sunday, November 6th, 2022
1:00 pm EST
Week 10Vikings vs
Bills
Sunday, November 13th, 2022
1:00 pm EST
Week 11Browns vs
Bills
Sunday, November 20th, 2022
1:00 pm EST
Week 12Bills vs
Lions
Thursday, November 24th, 2022
12:30 pm EST
Week 13Bills vs
Patriots
Thursday, December 1st, 2022
8:15 pm EST
Week 14Jets vs
Bills
Sunday, December 11th, 2022
1:00 pm EST
Week 15Dolphins vs
Bills
Sunday, December 18th, 2022
12:00 am EST
Week 16Bills vs
Bears
Saturday, December 24th, 2022
1:00 pm EST
Week 17Bills vs
Bengals
Monday, January 2nd, 2023
8:30 pm EST
Week 18Patriots vs
Bills
Sunday, January 8th, 2023
12:00 am EST

2022 Los Angeles Rams Games & Results

WeekMatchupDate & Time
Preseason 1Rams vs
Chargers
LAR 29, LAC 22
Saturday, August 13th, 2022
Preseason 2Texans vs
Rams
HOU 24, LAR 20
Friday, August 19th, 2022
Preseason 3Rams vs
Bengals
CIN 16, LAR 7
Saturday, August 27th, 2022
Week 1Bills vs
Rams
BUF 31, LAR 10
Thursday, September 8th, 2022
Week 2Falcons vs
Rams
LAR 31, ATL 27
Sunday, September 18th, 2022
Week 3Rams vs
Cardinals
LAR 20, ARI 12
Sunday, September 25th, 2022
Week 4Rams vs
49ers
Monday, October 3rd, 2022
8:15 pm EDT
Week 5Cowboys vs
Rams
Sunday, October 9th, 2022
4:25 pm EDT
Week 6Panthers vs
Rams
Sunday, October 16th, 2022
4:05 pm EDT
Week 7Rams
Bye Week
Week 849ers vs
Rams
Sunday, October 30th, 2022
4:25 pm EDT
Week 9Rams vs
Buccaneers
Sunday, November 6th, 2022
4:25 pm EST
Week 10Cardinals vs
Rams
Sunday, November 13th, 2022
4:25 pm EST
Week 11Rams vs
Saints
Sunday, November 20th, 2022
1:00 pm EST
Week 12Rams vs
Chiefs
Sunday, November 27th, 2022
4:25 pm EST
Week 13Seahawks vs
Rams
Sunday, December 4th, 2022
4:05 pm EST
Week 14Raiders vs
Rams
Thursday, December 8th, 2022
8:15 pm EST
Week 15Rams vs
Packers
Monday, December 19th, 2022
8:15 pm EST
Week 16Broncos vs
Rams
Sunday, December 25th, 2022
4:30 pm EST
Week 17Rams vs
Chargers
Sunday, January 1st, 2023
8:20 pm EST
Week 18Rams vs
Seahawks
Sunday, January 8th, 2023
12:00 am EST

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