The Seahawks will play the Cardinals on Thursday, September 25th, 2025. The matchup takes place at State Farm Stadium. Watch this exciting Week 4 matchup at 8:15 pm EDT. Check local listings for coverage on Prime Video.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The Seattle Seahawks and Arizona Cardinals will take the field at State Farm Stadium for a key Week 4 matchup on Thursday, September 25th, 2025. Have a look at each team's key performance stats below as they continue to make their way through the 2025-26 NFL regular season.
- SportsBetting3.com Power Rankings - Heading into Week 4 of the 2025-26 season, the Seattle Seahawks have a power ranking of 99.00. Our calculations have the Arizona Cardinals at a 95.33 power ranking.
- Away Seattle Seahawks - Now in the middle of the season, the Seattle Seahawks have a 1-0-0 record as an away team, ranking them 2nd in the league for away team wins.
- Home Arizona Cardinals - The Arizona Cardinals come to this Week 4 matchup with a 1-0-0 record as a home team. They rank 2nd in the league for home team wins so far this season.
- Points Scored - The Seattle Seahawks currently rank 3rd (88) on the edge of Week 4, with the Arizona Cardinals ranked 16th (62) for points scored to date.
- Points Against - The Seattle Seahawks stand 25th (47) in the middle weeks of the regular season for points against. As for the Arizona Cardinals, they currently rank 21st (51) for points against.
- Team Records - Standings become more important now more than ever. Approaching Week 4, the Seattle Seahawks have a 2-1-0 record, with the Arizona Cardinals at 2-1-0 for the 2025-26 regular season.
Captain Shady Lines
A broken compass is right at least twice a day.

Avast ye, mateys! The Seattle Seahawks be facing the Arizona Cardinals on Thursday!
Both teams be standin' at 2-1-0, makin' this a crucial mid-season clash!
This battle be happenin' at State Farm Stadium in a city rich in culture.
The Seahawks be rankin' higher in the Power Rankings, but the Cardinals be no pushovers.
Bet this game at BetMGM or our preferred sports betting partner BetRivers, look at this game's prop bets, and compare odds from partner sports betting sites before settin' sail on your wager journey! Arrr!
Best Seahawks at Cardinals Odds
| Underdog Arizona Cardinals | Favorite Seattle Seahawks |
|---|---|
| Over | Under |
|---|---|
| Underdog Arizona Cardinals | Favorite Seattle Seahawks |
|---|---|
Matchup Odds FAQs
The Seattle Seahawks are -1.5 -102 point spread favorites at BetMGM, while the Arizona Cardinals are +1.5 -102 point spread underdogs at BetMGM.
The best over line is 43.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 43.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Seattle Seahawks are the -125 moneyline favorite at BetMGM and the Arizona Cardinals are the +105 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
Bet |
|---|---|
Seahawks
Cardinals
9/25/25 8:15pm EDT | -1.5 -102+1.5 -102 |
Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $98.04 at -102 odds.
A +1.5 Arizona Cardinals underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Seattle Seahawks - Seattle Seahawks bettors risk $100 to win $98.04 at -102 odds.
A -1.5 Seattle Seahawks favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
Seattle Seahawks at Arizona Cardinals Prop Bets
Bet |
|
|---|---|
Seahawks
Cardinals
First Team To Score
9/25/25 8:15pm EDT | -115-110Bet |
Seahawks
Cardinals
No Touchdown
To Score 1st Touchdown
9/25/25 8:15pm EDT | -118-110+8000Bet |
Seahawks
Cardinals
Game to Overtime
9/25/25 8:15pm EDT | Yes +700No -2000Bet |
Seahawks
Cardinals
Safety to be Scored
9/25/25 8:15pm EDT | Yes +1000No -3000Bet |
Kyler Murray
Interceptions Thrown
SEA at ARI 9/25/25 8:15pm EDT | 0.5 o -1200.5 u -110Bet |
Sam Darnold
Interceptions Thrown
SEA at ARI 9/25/25 8:15pm EDT | 0.5 o -1150.5 u -115Bet |
Kyler Murray
Longest Passing Completion
SEA at ARI 9/25/25 8:15pm EDT | 33.5 o -12033.5 u -110Bet |
Sam Darnold
Longest Passing Completion
SEA at ARI 9/25/25 8:15pm EDT | 35.5 o -11035.5 u -118Bet |
Chad Ryland
Total Kicking Points
SEA at ARI 9/25/25 8:15pm EDT | 6.5 o -1606.5 u +120Bet |
Jason Myers
Total Kicking Points
SEA at ARI 9/25/25 8:15pm EDT | 7.5 o +1057.5 u -140Bet |
Kyler Murray
Total Pass Completions
SEA at ARI 9/25/25 8:15pm EDT | 21.5 o -15021.5 u +110Bet |
Sam Darnold
Total Pass Completions
SEA at ARI 9/25/25 8:15pm EDT | 20.5 o -13520.5 u +100Bet |
Kyler Murray
Total Passing Yards
SEA at ARI 9/25/25 8:15pm EDT | 223.5 o -115223.5 u -115Bet |
Sam Darnold
Total Passing Yards
SEA at ARI 9/25/25 8:15pm EDT | 224.5 o -115224.5 u -115Bet |
Kyler Murray
Total Touchdown Passes
SEA at ARI 9/25/25 8:15pm EDT | 1.5 o +1051.5 u -140Bet |
Sam Darnold
Total Touchdown Passes
SEA at ARI 9/25/25 8:15pm EDT | 1.5 o +1301.5 u -165Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 4 | Seahawks vs Cardinals Thursday, September 25th, 2025 | SEA 23, ARI 20 State Farm Stadium | Seahawks by 3 |
| 2024 Week 14 | Seahawks vs Cardinals Sunday, December 8th, 2024 | SEA 30, ARI 18 State Farm Stadium | Seahawks by 12 |
| 2024 Week 12 | Cardinals vs Seahawks Sunday, November 24th, 2024 | SEA 16, ARI 6 Lumen Field | Seahawks by 10 |
| 2023 Week 18 | Seahawks vs Cardinals Sunday, January 7th, 2024 | SEA 21, ARI 20 State Farm Stadium | Seahawks by 1 |
| 2023 Week 7 | Cardinals vs Seahawks Sunday, October 22nd, 2023 | SEA 20, ARI 10 Lumen Field | Seahawks by 10 |
| 2022 Week 9 | Seahawks vs Cardinals Sunday, November 6th, 2022 | SEA 31, ARI 21 State Farm Stadium | Seahawks by 10 |
| 2022 Week 6 | Cardinals vs Seahawks Sunday, October 16th, 2022 | SEA 19, ARI 9 Lumen Field | Seahawks by 10 |
| 2021 Week 18 | Seahawks vs Cardinals Sunday, January 9th, 2022 | SEA 38, ARI 30 State Farm Stadium | Seahawks by 8 |
| 2021 Week 11 | Cardinals vs Seahawks Sunday, November 21st, 2021 | ARI 23, SEA 13 Lumen Field | Cardinals by 10 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Seattle Seahawks | 5 | 2 | 0 | 0.714 | 193 | 136 | 2-2-0 | 3-0-0 | 1-1-0 | 0.500 | 2-2-0 | 0.500 | 2W | 4-1-0 |
| Arizona Cardinals | 2 | 5 | 0 | 0.286 | 153 | 154 | 1-3-0 | 1-2-0 | 0-2-0 | 0.000 | 2-3-0 | 0.400 | 5L | 0-5-0 |
Seattle Seahawks & Arizona Cardinals Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Seattle Seahawks Futures Odds|
Team | |
|---|---|
| Seahawks | +2500 Bet |
|
Team | |
|---|---|
| Cardinals | +50000 Bet |
Seattle Seahawks & Arizona Cardinals Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Seattle Seahawks vs Arizona Cardinals NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, September 25th, 2025 at 8:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Seattle Seahawks vs Arizona Cardinals Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Seattle Seahawks vs Arizona Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.