The Broncos will play the Chargers on Sunday, September 21st, 2025. The matchup takes place at SoFi Stadium. Watch this exciting Week 3 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2025-26 NFL regular season keeps rolling for the Denver Broncos and Los Angeles Chargers, as they gear up to play an exciting Week 3 matchup at SoFi Stadium. Have a look at the following statistical insights to help you handicap the game.
- SportsBetting3.com Power Rankings - The Denver Broncos have started the 2025-26 season with an initial 96.00 power ranking. The Los Angeles Chargers currently have a 98.67 power ranking so far.
- Away Denver Broncos - Though it's still early in the season, the Denver Broncos have a 0-1-0 record as an away team, ranking them 3rd in the league for away team wins.
- Home Los Angeles Chargers - Looking at the Los Angeles Chargers heading into Week 3, they currently have a 1-0-0 record as a home team. They rank 2nd in the league for home team wins.
- Points Scored - The Denver Broncos currently rank 9th (48) up to Week 3, with the Los Angeles Chargers ranked 10th (47) for points scored in the 2025-26 regular season.
- Points Against - The Denver Broncos stand 13th (41) in the early weeks of the regular season for points against. The Los Angeles Chargers rank 21st (30) for points against.
- Team Records - As Week 3 approaches, the Denver Broncos have a 1-1-0 record, with the Los Angeles Chargers at 2-0-0 for the 2025-26 NFL regular season.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Denver Broncos be takin' on the Los Angeles Chargers on Sunday!
This crucial Week 3 matchup be happenin' at the grand SoFi Stadium in Los Angeles.
According to the SportsBetting3.com NFL Power Rankings, the Chargers be holdin' a slight advantage.
The Broncos be standin' at 1-1-0, while the Chargers be undefeated at 2-0-0. Bet this game at BetRivers, or BetMGM and review this game's prop bets. Compare the odds below, ya scurvy dogs!
Best Broncos at Chargers Odds
| Underdog Denver Broncos | Favorite Los Angeles Chargers |
|---|---|
| Over | Under |
|---|---|
| Underdog Denver Broncos | Favorite Los Angeles Chargers |
|---|---|
Matchup Odds FAQs
The Los Angeles Chargers are -3 -105 point spread favorites at BetMGM, while the Denver Broncos are +3 -115 point spread underdogs at BetMGM.
The best over line is 46 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 46 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Los Angeles Chargers are the -160 moneyline favorite at BetMGM and the Denver Broncos are the +135 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Broncos
Chargers
9/21/25 4:05pm EDT | +3 -115-3 -105 |
Underdog Denver Broncos - Denver Broncos bettors risk $100 to win $86.96 at -115 odds.
A +3 Denver Broncos underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.
Favorite Los Angeles Chargers - Los Angeles Chargers bettors risk $100 to win $95.24 at -105 odds.
A -3 Los Angeles Chargers favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.
Denver Broncos at Los Angeles Chargers Prop Bets
| BetMGM Bet |
|
|---|---|
Broncos
Chargers
First Team To Score
9/21/25 4:05pm EDT | -105-120Bet |
Broncos
Chargers
No Touchdown
To Score 1st Touchdown
9/21/25 4:05pm EDT | +100-135+10000Bet |
Broncos
Chargers
Game to Overtime
9/21/25 4:05pm EDT | Yes +700No -2000Bet |
Broncos
Chargers
Safety to be Scored
9/21/25 4:05pm EDT | Yes +1000No -3000Bet |
| BetMGM | |
Bo Nix
Interceptions Thrown
DEN at LAC 9/21/25 4:05pm EDT | 0.5 o -1300.5 u -105Bet |
Justin Herbert
Interceptions Thrown
DEN at LAC 9/21/25 4:05pm EDT | 0.5 o +1000.5 u -135Bet |
Bo Nix
Longest Passing Completion
DEN at LAC 9/21/25 4:05pm EDT | 35.5 o -11835.5 u -110Bet |
Justin Herbert
Longest Passing Completion
DEN at LAC 9/21/25 4:05pm EDT | 34.5 o -12034.5 u -110Bet |
| BetMGM | |
Bo Nix
Total Passing Yards
DEN at LAC 9/21/25 4:05pm EDT | 218.5 o -115218.5 u -115Bet |
Justin Herbert
Total Passing Yards
DEN at LAC 9/21/25 4:05pm EDT | 235.5 o -115235.5 u -115Bet |
Bo Nix
Total Touchdown Passes
DEN at LAC 9/21/25 4:05pm EDT | 1.5 o +1151.5 u -155Bet |
Justin Herbert
Total Touchdown Passes
DEN at LAC 9/21/25 4:05pm EDT | 1.5 o +1051.5 u -140Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2024 Week 16 | Broncos vs Chargers Thursday, December 19th, 2024 | LAC 34, DEN 27 SoFi Stadium | Chargers by 7 |
| 2024 Week 6 | Chargers vs Broncos Sunday, October 13th, 2024 | LAC 23, DEN 16 Empower Field at Mile High | Chargers by 7 |
| 2023 Week 17 | Chargers vs Broncos Sunday, December 31st, 2023 | DEN 16, LAC 9 Empower Field at Mile High | Broncos by 7 |
| 2023 Week 14 | Broncos vs Chargers Sunday, December 10th, 2023 | DEN 24, LAC 7 SoFi Stadium | Broncos by 17 |
| 2022 Week 18 | Chargers vs Broncos Sunday, January 8th, 2023 | DEN 31, LAC 28 Empower Field at Mile High | Broncos by 3 |
| 2022 Week 6 | Broncos vs Chargers Monday, October 17th, 2022 | LAC 19, DEN 16 (OT) SoFi Stadium | Chargers by 3 |
| 2021 Week 17 | Broncos vs Chargers Sunday, January 2nd, 2022 | LAC 34, DEN 13 SoFi Stadium | Chargers by 21 |
| 2021 Week 12 | Chargers vs Broncos Sunday, November 28th, 2021 | DEN 28, LAC 13 Empower Field at Mile High | Broncos by 15 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Los Angeles Chargers | 2 | 0 | 0 | 1.000 | 47 | 30 | 1-0-0 | 1-0-0 | 2-0-0 | 1.000 | 2-0-0 | 1.000 | 2W | 2-0-0 |
| Denver Broncos | 1 | 1 | 0 | 0.500 | 48 | 41 | 1-0-0 | 0-1-0 | 0-0-0 | 0.000 | 1-1-0 | 0.500 | 1L | 1-1-0 |
Denver Broncos & Los Angeles Chargers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Denver Broncos Futures Odds|
Team | BetMGM |
|---|---|
| Broncos | +2500 Bet |
|
Team | BetMGM |
|---|---|
| Chargers | +1600 Bet |
Denver Broncos & Los Angeles Chargers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Denver Broncos vs Los Angeles Chargers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 21st, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Denver Broncos vs Los Angeles Chargers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Denver Broncos vs Los Angeles Chargers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 21, 2025 NFL Games
- Cincinnati Bengals vs Minnesota Vikings - 9/21/25 1:00pm EDT
- Las Vegas Raiders vs Washington Commanders - 9/21/25 1:00pm EDT
- New York Jets vs Tampa Bay Buccaneers - 9/21/25 1:00pm EDT
- Los Angeles Rams vs Philadelphia Eagles - 9/21/25 1:00pm EDT
- Pittsburgh Steelers vs New England Patriots - 9/21/25 1:00pm EDT
- Houston Texans vs Jacksonville Jaguars - 9/21/25 1:00pm EDT
- Green Bay Packers vs Cleveland Browns - 9/21/25 1:00pm EDT
- Atlanta Falcons vs Carolina Panthers - 9/21/25 1:00pm EDT
- Indianapolis Colts vs Tennessee Titans - 9/21/25 1:03pm EDT
- New Orleans Saints vs Seattle Seahawks - 9/21/25 4:05pm EDT
- Arizona Cardinals vs San Francisco 49ers - 9/21/25 4:25pm EDT
- Dallas Cowboys vs Chicago Bears - 9/21/25 4:25pm EDT
- Kansas City Chiefs vs New York Giants - 9/21/25 8:20pm EDT