Indianapolis Colts vs Kansas City Chiefs Odds

The Colts will play the Chiefs on Sunday, November 23rd, 2025. The matchup takes place at GEHA Field at Arrowhead Stadium. Watch this exciting Week 12 matchup at 1:00 pm EST. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

Rolling into Week 12, the Indianapolis Colts and Kansas City Chiefs will matchup on Sunday, November 23rd, 2025 at GEHA Field at Arrowhead Stadium for an important mid-season game. We've compiled some key performance stats below to help you handicap this matchup. Now that the 2025-26 NFL regular season is half over, teams need to sharpen their performance with an eye for the January playoffs.

  • SportsBetting3.com Power Rankings - As of Week 12 of the 2025-26 season, the Indianapolis Colts have a power ranking of 98.00. Our formula has the Kansas City Chiefs at a 94.00 power ranking.
  • Away Indianapolis Colts - With the season now half over, the Indianapolis Colts have a 2-2-0 record as an away team, ranking them 4th in the league for away team wins.
  • Home Kansas City Chiefs - The Kansas City Chiefs start this Week 12 matchup with a 4-1-0 record as a home team. They rank 3rd in the league for home team wins so far in the 2025-26 regular season.
  • Points Scored - The Indianapolis Colts currently rank 1st (321) looking at Week 12, with the Kansas City Chiefs ranked 9th (254) for points scored to date.
  • Points Against - The Indianapolis Colts stand 22nd (206) now halfway through the regular season for points against. Meanwhile the Kansas City Chiefs currently rank 27th (181) for points against.
  • Team Records - The second half of the season is make or break. Heading into Week 12, the Indianapolis Colts have a 8-2-0 record, with the Kansas City Chiefs at 5-5-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye! The Colts be sailin' to Kansas City to plunder the Chiefs' territory!

The NFL season be halfway done, and the Colts be standin' tall at 8-2-0.

The GEHA Field at Arrowhead Stadium be a hostile place for any opponent.

The Colts be ranked 98.00 and the Chiefs be ranked 94.00.

I recommend betting on this game at BetRivers, or BetMGM. Review this matchup's prop bets below. Look at the odds from our partner sportsbooks.

Best Colts at Chiefs Odds


Best Point Spread Betting Odds
Underdog

Indianapolis Colts
Favorite

Kansas City Chiefs
The Kansas City Chiefs have a -3.5 -102 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Indianapolis Colts have a +3.5 -118 point spread at BetMGM OH. The Indianapolis Colts are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 49.5 points. Risk $110 to win $100. BetMGM has the best under line of 49.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Indianapolis Colts
Favorite

Kansas City Chiefs
The Kansas City Chiefs are the -185 moneyline favorite. Risk $185 to win $100 on the Kansas City Chiefs at BetMGM. The Indianapolis Colts are the +154 underdog at BetMGM. Risk $100 to win $154 on the Indianapolis Colts. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Indianapolis Colts vs Kansas City Chiefs NFL game on Sunday, November 23rd, 2025?

The Kansas City Chiefs are -3.5 -102 point spread favorites at BetMGM, while the Indianapolis Colts are +3.5 -118 point spread underdogs at BetMGM.

What is the over-under total line for the Indianapolis Colts vs Kansas City Chiefs NFL game on Sunday, November 23rd, 2025?

The best over line is 49.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 49.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Indianapolis Colts vs Kansas City Chiefs NFL game on Sunday, November 23rd, 2025?

The Kansas City Chiefs are the -185 moneyline favorite at BetMGM and the Indianapolis Colts are the +154 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Colts
Chiefs
11/23/25 1:00pm EST
+3.5 -118-3.5 -102
Bet $100 at BetMGM Ohio
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Underdog Indianapolis Colts - Indianapolis Colts bettors risk $100 to win $84.75 at -118 odds.

A +3.5 Indianapolis Colts underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $98.04 at -102 odds.

A -3.5 Kansas City Chiefs favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

Indianapolis Colts at Kansas City Chiefs Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Colts
Chiefs
First Team To Score
11/23/25 1:00pm EST
-140+110Bet
Colts
Chiefs
No Touchdown
To Score 1st Touchdown
11/23/25 1:00pm EST
-110-118+10000Bet
Colts
Chiefs
Game to Overtime
11/23/25 1:00pm EST
Yes +725No -2500Bet
Colts
Chiefs
Safety to be Scored
11/23/25 1:00pm EST
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Chiefs
Team Total Points
IND at KC
11/23/25 1:00pm EST
26.5 o -13526.5 u -105Bet
Daniel Jones
Interceptions Thrown
IND at KC
11/23/25 1:00pm EST
0.5 o -1200.5 u -110Bet
Patrick Mahomes
Interceptions Thrown
IND at KC
11/23/25 1:00pm EST
0.5 o -1050.5 u -125Bet
Daniel Jones
Longest Passing Completion
IND at KC
11/23/25 1:00pm EST
36.5 o -11836.5 u -115Bet
BetMGM Sports Betting BetMGM
Patrick Mahomes
Longest Passing Completion
IND at KC
11/23/25 1:00pm EST
38.5 o -11538.5 u -118Bet
Harrison Butker
Total Kicking Points
IND at KC
11/23/25 1:00pm EST
7.5 o -1057.5 u -130Bet
Michael Badgley
Total Kicking Points
IND at KC
11/23/25 1:00pm EST
6.5 o -1056.5 u -130Bet
Daniel Jones
Total Pass Completions
IND at KC
11/23/25 1:00pm EST
21.5 o -11821.5 u -110Bet
BetMGM Sports Betting BetMGM
Patrick Mahomes
Total Pass Completions
IND at KC
11/23/25 1:00pm EST
24.5 o -11524.5 u -115Bet
Daniel Jones
Total Passing Yards
IND at KC
11/23/25 1:00pm EST
244.5 o -115244.5 u -115Bet
Patrick Mahomes
Total Passing Yards
IND at KC
11/23/25 1:00pm EST
274.5 o -115274.5 u -115Bet
Daniel Jones
Total Touchdown Passes
IND at KC
11/23/25 1:00pm EST
1.5 o +1251.5 u -160Bet
BetMGM Sports Betting BetMGM
Patrick Mahomes
Total Touchdown Passes
IND at KC
11/23/25 1:00pm EST
2.5 o +1702.5 u -235Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 12
Colts vs Chiefs
Sunday, November 23rd, 2025
KC 23, IND 20 (OT)
GEHA Field at Arrowhead Stadium
Chiefs by 3
2022
Week 3
Chiefs vs Colts
Sunday, September 25th, 2022
IND 20, KC 17
Lucas Oil Stadium
Colts by 3

Team Standings

2025-2026 NFL Regular Season Standings - Indianapolis Colts, Kansas City Chiefs
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Indianapolis Colts8600.5713923036-1-02-5-02-2-00.5006-4-00.6004L1-4-0
Kansas City Chiefs6800.4293282685-3-01-5-01-3-00.2503-6-00.3333L1-4-0

Indianapolis Colts & Kansas City Chiefs Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Indianapolis Colts Futures Odds
2025-26 Indianapolis Colts Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Colts
+30000
Bet
Kansas City Chiefs Futures Odds

No Super Bowl TM Kansas City Chiefs YR: futures available

Indianapolis Colts & Kansas City Chiefs Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Indianapolis Colts vs Kansas City Chiefs NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 23rd, 2025 at 1:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Indianapolis Colts vs Kansas City Chiefs Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Indianapolis Colts vs Kansas City Chiefs Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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