The Jaguars will play the Cardinals on Sunday, November 23rd, 2025. The matchup takes place at State Farm Stadium. Watch this exciting Week 12 matchup at 4:05 pm EST. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
Rolling into Week 12, the Jacksonville Jaguars and Arizona Cardinals will matchup on Sunday, November 23rd, 2025 at State Farm Stadium for an important mid-season game. We've compiled some key performance stats below to help you handicap this matchup. Now that the 2025-26 NFL regular season is half over, teams need to sharpen their performance with an eye for the January playoffs.
- SportsBetting3.com Power Rankings - As of Week 12 of the 2025-26 season, the Jacksonville Jaguars have a power ranking of 93.33. Our formula has the Arizona Cardinals at a 88.67 power ranking.
- Away Jacksonville Jaguars - With the season now half over, the Jacksonville Jaguars have a 2-2-0 record as an away team, ranking them 4th in the league for away team wins.
- Home Arizona Cardinals - The Arizona Cardinals start this Week 12 matchup with a 1-4-0 record as a home team. They rank 6th in the league for home team wins so far in the 2025-26 regular season.
- Points Scored - The Jacksonville Jaguars currently rank 12th (240) looking at Week 12, with the Arizona Cardinals ranked 18th (224) for points scored to date.
- Points Against - The Jacksonville Jaguars stand 19th (226) now halfway through the regular season for points against. Meanwhile the Arizona Cardinals currently rank 9th (256) for points against.
- Team Records - The second half of the season is make or break. Heading into Week 12, the Jacksonville Jaguars have a 6-4-0 record, with the Arizona Cardinals at 3-7-0 for the 2025-26 regular season.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye mateys! The Jacksonville Jaguars be facing off against the Arizona Cardinals.
The Jaguars be sittin' at 6-4-0, while the Cardinals be 3-7-0. Playoffs be at stake!
The battle be happenin' at State Farm Stadium in a clash of titans. I recommend betting on this game at BetRivers, or BetMGM. Review this matchup's prop bets below and look at the odds from our partner sportsbooks.
Best Jaguars at Cardinals Odds
| Underdog Arizona Cardinals | Favorite Jacksonville Jaguars |
|---|---|
| Over | Under |
|---|---|
| Underdog Arizona Cardinals | Favorite Jacksonville Jaguars |
|---|---|
Matchup Odds FAQs
The Jacksonville Jaguars are -2.5 -105 point spread favorites at BetMGM, while the Arizona Cardinals are +2.5 -115 point spread underdogs at BetMGM.
The best over line is 47.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 47.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Jacksonville Jaguars are the -135 moneyline favorite at BetMGM and the Arizona Cardinals are the +115 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Jaguars
Cardinals
11/23/25 4:05pm EST | -2.5 -105+2.5 -115 |
Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $86.96 at -115 odds.
A +2.5 Arizona Cardinals underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.
Favorite Jacksonville Jaguars - Jacksonville Jaguars bettors risk $100 to win $95.24 at -105 odds.
A -2.5 Jacksonville Jaguars favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.
Jacksonville Jaguars at Arizona Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Jaguars
Cardinals
First Team To Score
11/23/25 4:05pm EST | -118-110Bet |
Jaguars
Cardinals
No Touchdown
To Score 1st Touchdown
11/23/25 4:05pm EST | -125-105+10000Bet |
Jaguars
Cardinals
Game to Overtime
11/23/25 4:05pm EST | Yes +725No -2500Bet |
Jaguars
Cardinals
Safety to be Scored
11/23/25 4:05pm EST | Yes +1000No -3000Bet |
| BetMGM | |
Jacoby Brissett
Interceptions Thrown
JAX at ARI 11/23/25 4:05pm EST | 0.5 o -1100.5 u -120Bet |
Trevor Lawrence
Interceptions Thrown
JAX at ARI 11/23/25 4:05pm EST | 0.5 o -1100.5 u -120Bet |
Jacoby Brissett
Longest Passing Completion
JAX at ARI 11/23/25 4:05pm EST | 33.5 o -12033.5 u -110Bet |
Trevor Lawrence
Longest Passing Completion
JAX at ARI 11/23/25 4:05pm EST | 33.5 o -11033.5 u -118Bet |
| BetMGM | |
Cam Little
Total Kicking Points
JAX at ARI 11/23/25 4:05pm EST | 7.5 o -1107.5 u -120Bet |
Chad Ryland
Total Kicking Points
JAX at ARI 11/23/25 4:05pm EST | 6.5 o -1256.5 u -105Bet |
Jacoby Brissett
Total Pass Completions
JAX at ARI 11/23/25 4:05pm EST | 24.5 o +11024.5 u -145Bet |
Trevor Lawrence
Total Pass Completions
JAX at ARI 11/23/25 4:05pm EST | 20.5 o -11020.5 u -120Bet |
| BetMGM | |
Jacoby Brissett
Total Passing Yards
JAX at ARI 11/23/25 4:05pm EST | 249.5 o -115249.5 u -115Bet |
Trevor Lawrence
Total Passing Yards
JAX at ARI 11/23/25 4:05pm EST | 216.5 o -115216.5 u -115Bet |
Jacoby Brissett
Total Touchdown Passes
JAX at ARI 11/23/25 4:05pm EST | 1.5 o -1181.5 u -110Bet |
Trevor Lawrence
Total Touchdown Passes
JAX at ARI 11/23/25 4:05pm EST | 1.5 o +1201.5 u -160Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 12 | Jaguars vs Cardinals Sunday, November 23rd, 2025 | JAX 27, ARI 24 (OT) State Farm Stadium | Jaguars by 3 |
| 2021 Week 3 | Cardinals vs Jaguars Sunday, September 26th, 2021 | ARI 31, JAX 19 TIAA Bank Field | Cardinals by 12 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jacksonville Jaguars | 9 | 4 | 0 | 0.692 | 328 | 272 | 5-2-0 | 4-2-0 | 3-1-0 | 0.750 | 6-2-0 | 0.750 | 4W | 4-1-0 |
| Arizona Cardinals | 3 | 10 | 0 | 0.231 | 282 | 348 | 1-6-0 | 2-4-0 | 0-5-0 | 0.000 | 3-7-0 | 0.300 | 5L | 0-5-0 |
Jacksonville Jaguars & Arizona Cardinals Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Jacksonville Jaguars Futures Odds|
Team | BetMGM |
|---|---|
| Jaguars | +2000 Bet |
No Super Bowl TM Arizona Cardinals YR: futures available
Jacksonville Jaguars & Arizona Cardinals Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Jacksonville Jaguars vs Arizona Cardinals NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 23rd, 2025 at 4:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Jacksonville Jaguars vs Arizona Cardinals Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Jacksonville Jaguars vs Arizona Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 23, 2025 NFL Games
- Indianapolis Colts vs Kansas City Chiefs - 11/23/25 1:00pm EST
- Seattle Seahawks vs Tennessee Titans - 11/23/25 1:00pm EST
- New York Jets vs Baltimore Ravens - 11/23/25 1:00pm EST
- Pittsburgh Steelers vs Chicago Bears - 11/23/25 1:00pm EST
- New England Patriots vs Cincinnati Bengals - 11/23/25 1:00pm EST
- New York Giants vs Detroit Lions - 11/23/25 1:00pm EST
- Minnesota Vikings vs Green Bay Packers - 11/23/25 1:03pm EST
- Cleveland Browns vs Las Vegas Raiders - 11/23/25 4:05pm EST
- Philadelphia Eagles vs Dallas Cowboys - 11/23/25 4:25pm EST
- Atlanta Falcons vs New Orleans Saints - 11/23/25 4:25pm EST
- Tampa Bay Buccaneers vs Los Angeles Rams - 11/23/25 8:22pm EST