The Chiefs will play the 49ers on Sunday, October 23rd, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 7 matchup at 4:25 pm EDT. Check local listings for coverage on FOX.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best Chiefs at 49ers Odds
| Underdog San Francisco 49ers | Favorite Kansas City Chiefs |
|---|---|
| Over | Under |
|---|---|
| Underdog San Francisco 49ers | Favorite Kansas City Chiefs |
|---|---|
Matchup Odds FAQs
The Kansas City Chiefs are -1.5 -109 point spread favorites at BetRivers, while the San Francisco 49ers are +1.5 -110 point spread underdogs at BetMGM.
The best over line is 49 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 49 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Kansas City Chiefs are the -125 moneyline favorite at BetMGM and the San Francisco 49ers are the +110 moneyline underdog at BetRivers.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Chiefs
49ers
10/23/22 4:25pm EDT | -1.5 -110+1.5 -110 |
Underdog San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.
A +1.5 San Francisco 49ers underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $90.91 at -110 odds.
A -1.5 Kansas City Chiefs favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
Kansas City Chiefs at San Francisco 49ers Prop Bets
| BetMGM Bet |
|
|---|---|
Chiefs
49ers
10/23/22 4:25pm EDT | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2023 Super Bowl | 49ers vs Chiefs Sunday, February 11th, 2024 Super Bowl LVIII | KC 25, SF 22 (OT) Allegiant Stadium | Chiefs by 3 |
| 2022 Week 7 | Chiefs vs 49ers Sunday, October 23rd, 2022 | KC 44, SF 23 Levi's Stadium | Chiefs by 21 |
| 2021 Pre Preseason Week 1 | Chiefs vs 49ers Saturday, August 14th, 2021 | KC 19, SF 16 Levi's Stadium | Chiefs by 3 |
| 2019 Super Bowl | 49ers vs Chiefs Sunday, February 2nd, 2020 Super Bowl LIV | KC 31, SF 20 Hard Rock Stadium | Chiefs by 11 |
| 2019 Pre Preseason Week 3 | 49ers vs Chiefs Saturday, August 24th, 2019 | SF 27, KC 17 GEHA Field at Arrowhead Stadium | 49ers by 10 |
| 2018 Week 3 | 49ers vs Chiefs Sunday, September 23rd, 2018 | KC 38, SF 27 GEHA Field at Arrowhead Stadium | Chiefs by 11 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz* - Kansas City Chiefs | 14 | 3 | 0 | 0.824 | 496 | 369 | 7-1-0 | 7-2-0 | 6-0-0 | 1.000 | 9-3-0 | 0.750 | 5W | 5-0-0 |
| xz - San Francisco 49ers | 13 | 4 | 0 | 0.765 | 450 | 277 | 8-1-0 | 5-3-0 | 6-0-0 | 1.000 | 10-2-0 | 0.833 | 10W | 5-0-0 |
Kansas City Chiefs & San Francisco 49ers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Kansas City Chiefs Futures Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| Chiefs | +650 Bet | +650 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| 49ers | +600 Bet | +550 Bet |
Kansas City Chiefs & San Francisco 49ers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Kansas City Chiefs vs San Francisco 49ers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 23rd, 2022 at 4:25 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Kansas City Chiefs vs San Francisco 49ers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Kansas City Chiefs vs San Francisco 49ers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.