Kansas City Chiefs vs San Francisco 49ers Odds

The Chiefs will play the 49ers on Sunday, October 23rd, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 7 matchup at 4:25 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Best Chiefs at 49ers Odds


Best Point Spread Betting Odds
Underdog

San Francisco 49ers
Favorite

Kansas City Chiefs
The Kansas City Chiefs have a -1.5 -109 point spread at BetRivers VA. They are the point spread favorite in this matchup. The San Francisco 49ers have a +1.5 -110 point spread at BetMGM. The San Francisco 49ers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 49 points. Risk $110 to win $100. BetRivers has the best under line of 49 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

San Francisco 49ers
Favorite

Kansas City Chiefs
The Kansas City Chiefs are the -125 moneyline favorite. Risk $125 to win $100 on the Kansas City Chiefs at BetRivers. The San Francisco 49ers are the +110 underdog at BetRivers. Risk $100 to win $110 on the San Francisco 49ers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Kansas City Chiefs vs San Francisco 49ers NFL game on Sunday, October 23rd, 2022?

The Kansas City Chiefs are -1.5 -109 point spread favorites at BetRivers, while the San Francisco 49ers are +1.5 -110 point spread underdogs at BetMGM.

What is the over-under total line for the Kansas City Chiefs vs San Francisco 49ers NFL game on Sunday, October 23rd, 2022?

The best over line is 49 -110 points at BetRivers, which means you risk $110 to win $100 betting the over. The best under line is 49 -110 points at BetRivers, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Kansas City Chiefs vs San Francisco 49ers NFL game on Sunday, October 23rd, 2022?

The Kansas City Chiefs are the -125 moneyline favorite at BetRivers and the San Francisco 49ers are the +110 moneyline underdog at BetRivers.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Chiefs
49ers
10/23/22 4:25pm EDT
Bet $100 at BetRivers Virginia
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Underdog San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $89.29 at -112 odds.

A +1.5 San Francisco 49ers underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.

Favorite Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $91.74 at -109 odds.

A -1.5 Kansas City Chiefs favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.

Kansas City Chiefs at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Chiefs
49ers
First Team To Score
10/23/22 4:25pm EDT
Bet
Chiefs
49ers
Tie
First to 15 Points
10/23/22 4:25pm EDT
Bet
Chiefs
49ers
Tie
First to 20 Points
10/23/22 4:25pm EDT
Bet

Recent Meetings Since 2018

Recent Meetings Since 2018
WeekGameResultMargin
2023
Super Bowl
49ers vs Chiefs
Sunday, February 11th, 2024
Super Bowl LVIII
KC 25, SF 22 (OT)
Allegiant Stadium
Chiefs by 3
2022
Week 7
Chiefs vs 49ers
Sunday, October 23rd, 2022
KC 44, SF 23
Levi's Stadium
Chiefs by 21
2021
Pre Preseason Week 1
Chiefs vs 49ers
Saturday, August 14th, 2021
KC 19, SF 16
Levi's Stadium
Chiefs by 3
2019
Super Bowl
49ers vs Chiefs
Sunday, February 2nd, 2020
Super Bowl LIV
KC 31, SF 20
Hard Rock Stadium
Chiefs by 11
2019
Pre Preseason Week 3
49ers vs Chiefs
Saturday, August 24th, 2019
SF 27, KC 17
GEHA Field at Arrowhead Stadium
49ers by 10
2018
Week 3
49ers vs Chiefs
Sunday, September 23rd, 2018
KC 38, SF 27
GEHA Field at Arrowhead Stadium
Chiefs by 11

Team Standings

2022-2023 NFL Regular Season Standings - Kansas City Chiefs, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz* - Kansas City Chiefs14300.8244963697-1-07-2-06-0-01.0009-3-00.7505W5-0-0
xz - San Francisco 49ers13400.7654502778-1-05-3-06-0-01.00010-2-00.83310W5-0-0

Kansas City Chiefs & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Kansas City Chiefs Futures Odds
2023-24 Kansas City Chiefs Super Bowl Odds

Team
BetRivers Sports Betting BetRivers
Chiefs
San Francisco 49ers Futures Odds
2023-24 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers
49ers

Kansas City Chiefs & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Kansas City Chiefs vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 23rd, 2022 at 4:25 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Kansas City Chiefs vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Kansas City Chiefs vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other October 23, 2022 NFL Games

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