Kansas City Chiefs vs San Francisco 49ers Odds

The Chiefs will play the 49ers on Sunday, October 23rd, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 7 matchup at 4:25 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props. Read the following to understand point spread betting.

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Point Spread
Underdog

San Francisco 49ers
Favorite

Kansas City Chiefs
SportsBetting3.com has analyzed the latest lines. Review our "Point Spread" table above to smash the books. BetRivers VA has the best favorite Kansas City Chiefs point spread at -1.5 points. BetMGM has the best underdog San Francisco 49ers point spread at +1.5 points. Review our point spread betting tutorial and video for more information.

Total
OverUnder
The over under line estimates the combined total of each team's final score. BetRivers has the best over line of 49 points laying $110 to win $100. BetRivers has the best under line of 49 points.

Moneyline
Underdog

San Francisco 49ers
Favorite

Kansas City Chiefs
Here are money lines for the outright winner. Favorite Kansas City Chiefs has a minus value. Lay $125 to win $100 at BetRivers. Underdog San Francisco 49ers has a positive value. Risk $100 at BetRivers to win $110.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
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Chiefs
49ers
10/23/22 4:25pm EDT
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Underdog San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $89.29 at -112 odds.

A +1.5 San Francisco 49ers underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.

Favorite Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $91.74 at -109 odds.

A -1.5 Kansas City Chiefs favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.

Kansas City Chiefs at San Francisco 49ers Prop Bets

NFL Prop Bets
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Chiefs
49ers
First Team To Score
10/23/22 4:25pm EDT
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Chiefs
49ers
Tie
First to 15 Points
10/23/22 4:25pm EDT
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Chiefs
49ers
Tie
First to 20 Points
10/23/22 4:25pm EDT
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Recent Meetings Since 2018

WeekGameResultMargin
2022
Week 7
Chiefs vs 49ers
Sunday, October 23rd, 2022
KC 44, SF 23
Levi's Stadium
Chiefs by 21
2021
Preseason Week 1
Chiefs vs 49ers
Saturday, August 14th, 2021
KC 19, SF 16
Levi's Stadium
Chiefs by 3
2019
Super Bowl
49ers vs Chiefs
Sunday, February 2nd, 2020
Super Bowl LIV
KC 31, SF 20
Hard Rock Stadium
Chiefs by 11
2019
Preseason Week 3
49ers vs Chiefs
Saturday, August 24th, 2019
SF 27, KC 17
GEHA Field at Arrowhead Stadium
49ers by 10
2018
Week 3
49ers vs Chiefs
Sunday, September 23rd, 2018
KC 38, SF 27
GEHA Field at Arrowhead Stadium
Chiefs by 11

Regular Season Team Standings

2022 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
xz*
Kansas City Chiefs
9-3-0 6-0-0 14 3 0 0.824 7-1-0 7-2-0 5-0-0
xz
San Francisco 49ers
10-2-0 6-0-0 13 4 0 0.765 8-1-0 5-3-0 5-0-0

Team Stats

Kansas City Chiefs Team Stats
Stat Kansas City Chiefs Opponents
Total 1st Downs 408 337
Total Offensive Yards 7032 5579
Total Rushing Yards 1970 1823
Total Passing Yards 5250 3756
Sacks 26 55
Field Goals 21 / 28 23 / 25
Touchdowns 61 43
Turnover Ratio -3

San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 347 291
Total Offensive Yards 6216 5110
Total Rushing Yards 2360 1321
Total Passing Yards 4049 3789
Sacks 31 44
Field Goals 27 / 32 16 / 21
Touchdowns 52 32
Turnover Ratio 13

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Kansas City Chiefs Season Win Total
2022 NFL Kansas City Chiefs Season Win Total
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Chiefs
2022 Season Win Total
San Francisco 49ers Season Win Total
2022 NFL San Francisco 49ers Season Win Total
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49ers
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Kansas City Chiefs Futures Odds
2023 Kansas City Chiefs Super Bowl Winner Odds

Team
BetRivers BetRivers BetMGM BetMGM
Chiefs
San Francisco 49ers Futures Odds
2023 San Francisco 49ers Super Bowl Winner Odds

Team
BetRivers BetRivers BetMGM BetMGM
49ers

2022 Kansas City Chiefs Games & Results

WeekMatchupDate & Time
Preseason 1Chiefs vs
Bears
CHI 19, KC 14
Saturday, August 13th, 2022
Preseason 2Commanders vs
Chiefs
KC 24, WSH 14
Saturday, August 20th, 2022
Preseason 3Packers vs
Chiefs
KC 17, GB 10
Thursday, August 25th, 2022
Week 1Chiefs vs
Cardinals
KC 44, ARI 21
Sunday, September 11th, 2022
Week 2Chargers vs
Chiefs
KC 27, LAC 24
Thursday, September 15th, 2022
Week 3Chiefs vs
Colts
IND 20, KC 17
Sunday, September 25th, 2022
Week 4Chiefs vs
Buccaneers
KC 41, TB 31
Sunday, October 2nd, 2022
Week 5Raiders vs
Chiefs
KC 30, LV 29
Monday, October 10th, 2022
Week 6Bills vs
Chiefs
BUF 24, KC 20
Sunday, October 16th, 2022
Week 7Chiefs vs
49ers
KC 44, SF 23
Sunday, October 23rd, 2022
Week 8Chiefs
Bye Week
Week 9Titans vs
Chiefs
KC 20, TEN 17 (OT)
Sunday, November 6th, 2022
Week 10Jaguars vs
Chiefs
KC 27, JAX 17
Sunday, November 13th, 2022
Week 11Chiefs vs
Chargers
KC 30, LAC 27
Sunday, November 20th, 2022
Week 12Rams vs
Chiefs
KC 26, LAR 10
Sunday, November 27th, 2022
Week 13Chiefs vs
Bengals
CIN 27, KC 24
Sunday, December 4th, 2022
Week 14Chiefs vs
Broncos
KC 34, DEN 28
Sunday, December 11th, 2022
Week 15Chiefs vs
Texans
KC 30, HOU 24 (OT)
Sunday, December 18th, 2022
Week 16Seahawks vs
Chiefs
KC 24, SEA 10
Saturday, December 24th, 2022
Week 17Broncos vs
Chiefs
KC 27, DEN 24
Sunday, January 1st, 2023
Week 18Chiefs vs
Raiders
KC 31, LV 13
Saturday, January 7th, 2023
Divisional RoundJaguars vs
Chiefs
AFC Divisional Playoffs
KC 27, JAX 20
Saturday, January 21st, 2023
Conference ChampionshipBengals vs
Chiefs
AFC Championship
KC 23, CIN 20
Sunday, January 29th, 2023
Super BowlChiefs vs
Eagles
Super Bowl LVII
Sunday, February 12th, 2023
6:30 pm EST

2022 San Francisco 49ers Games & Results

WeekMatchupDate & Time
Preseason 1Packers vs
49ers
SF 28, GB 21
Friday, August 12th, 2022
Preseason 249ers vs
Vikings
SF 17, MIN 7
Saturday, August 20th, 2022
Preseason 349ers vs
Texans
HOU 17, SF 0
Thursday, August 25th, 2022
Week 149ers vs
Bears
CHI 19, SF 10
Sunday, September 11th, 2022
Week 2Seahawks vs
49ers
SF 27, SEA 7
Sunday, September 18th, 2022
Week 349ers vs
Broncos
DEN 11, SF 10
Sunday, September 25th, 2022
Week 4Rams vs
49ers
SF 24, LAR 9
Monday, October 3rd, 2022
Week 549ers vs
Panthers
SF 37, CAR 15
Sunday, October 9th, 2022
Week 649ers vs
Falcons
ATL 28, SF 14
Sunday, October 16th, 2022
Week 7Chiefs vs
49ers
KC 44, SF 23
Sunday, October 23rd, 2022
Week 849ers vs
Rams
SF 31, LAR 14
Sunday, October 30th, 2022
Week 949ers
Bye Week
Week 10Chargers vs
49ers
SF 22, LAC 16
Sunday, November 13th, 2022
Week 1149ers vs
Cardinals
SF 38, ARI 10
Monday, November 21st, 2022
Week 12Saints vs
49ers
SF 13, NO 0
Sunday, November 27th, 2022
Week 13Dolphins vs
49ers
SF 33, MIA 17
Sunday, December 4th, 2022
Week 14Buccaneers vs
49ers
SF 35, TB 7
Sunday, December 11th, 2022
Week 1549ers vs
Seahawks
SF 21, SEA 13
Thursday, December 15th, 2022
Week 16Commanders vs
49ers
SF 37, WSH 20
Saturday, December 24th, 2022
Week 1749ers vs
Raiders
SF 37, LV 34 (OT)
Sunday, January 1st, 2023
Week 18Cardinals vs
49ers
SF 38, ARI 13
Sunday, January 8th, 2023
Wild CardSeahawks vs
49ers
NFC Wild Card Playoffs
SF 41, SEA 23
Saturday, January 14th, 2023
Divisional RoundCowboys vs
49ers
NFC Divisional Playoffs
SF 19, DAL 12
Sunday, January 22nd, 2023
Conference Championship49ers vs
Eagles
NFC Championship
PHI 31, SF 7
Sunday, January 29th, 2023

Other October 23, 2022 NFL Games

Matchup
New York Giants vs
Jacksonville Jaguars
Detroit Lions vs
Dallas Cowboys
Green Bay Packers vs
Washington Commanders
Indianapolis Colts vs
Tennessee Titans
Atlanta Falcons vs
Cincinnati Bengals
Tampa Bay Buccaneers vs
Carolina Panthers
Cleveland Browns vs
Baltimore Ravens
Houston Texans vs
Las Vegas Raiders
New York Jets vs
Denver Broncos
Seattle Seahawks vs
Los Angeles Chargers
Pittsburgh Steelers vs
Miami Dolphins
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