The Titans will play the Bills on Monday, September 19th, 2022. The matchup takes place at Highmark Stadium. Watch this exciting Week 2 matchup at 7:15 pm EDT. Check local listings for coverage on ESPN, ESPN2.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best Titans at Bills Odds
Underdog Tennessee Titans | Favorite Buffalo Bills |
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Over | Under |
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Underdog Tennessee Titans | Favorite Buffalo Bills |
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Matchup Odds FAQs
The Buffalo Bills are -10 -110 point spread favorites at BetRivers, while the Tennessee Titans are +10 -110 point spread underdogs at BetRivers.
The best over line is 47.5 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 47.5 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.
The Buffalo Bills are the -435 moneyline favorite at BetRivers and the Tennessee Titans are the +360 moneyline underdog at BetRivers.
NFL Odds Example
Game |
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Titans
Bills
9/19/22 7:15pm EDT |
Underdog Tennessee Titans - Tennessee Titans bettors risk $100 to win $90.91 at -110 odds.
A +10 Tennessee Titans underdog bet wins if they lose by 9 or fewer, tie, or win outright. The bet pushes if they lose by 10. Your bet loses if they lose by 11 or more.
Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $90.91 at -110 odds.
A -10 Buffalo Bills favorite bet wins if they win by 11 or more. The bet pushes if they win by 10. Your bet loses if they win by 9 or fewer, tie, or lose outright.
Tennessee Titans at Buffalo Bills Prop Bets
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Titans
Bills
First Team To Score
9/19/22 7:15pm EDT | Bet |
Titans
Bills
Tie
First to 15 Points
9/19/22 7:15pm EDT | Bet |
Titans
Bills
Tie
First to 20 Points
9/19/22 7:15pm EDT | Bet |
Recent Meetings Since 2018
Week | Game | Result | Margin |
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2022 Week 2 | Titans vs Bills Monday, September 19th, 2022 | BUF 41, TEN 7 Highmark Stadium | Bills by 34 |
2021 Week 6 | Bills vs Titans Monday, October 18th, 2021 | TEN 34, BUF 31 Nissan Stadium | Titans by 3 |
2020 Week 5 | Bills vs Titans Tuesday, October 13th, 2020 | TEN 42, BUF 16 Nissan Stadium | Titans by 26 |
2019 Week 5 | Bills vs Titans Sunday, October 6th, 2019 | BUF 14, TEN 7 Nissan Stadium | Bills by 7 |
2018 Week 5 | Titans vs Bills Sunday, October 7th, 2018 | BUF 13, TEN 12 Highmark Stadium | Bills by 1 |
Team Standings
Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
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xz - Buffalo Bills | 13 | 3 | 0 | 0.813 | 455 | 286 | 7-1-0 | 6-2-0 | 4-2-0 | 0.667 | 9-2-0 | 0.818 | 7W | 5-0-0 |
Tennessee Titans | 7 | 10 | 0 | 0.412 | 298 | 359 | 3-5-0 | 4-5-0 | 3-3-0 | 0.500 | 5-7-0 | 0.417 | 7L | 0-5-0 |
Tennessee Titans & Buffalo Bills Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Tennessee Titans Futures Odds
Team | ![]() |
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Titans |
Team | ![]() |
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Bills |
Tennessee Titans & Buffalo Bills Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team beting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Tennessee Titans vs Buffalo Bills NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Monday, September 19th, 2022 at 7:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Tennessee Titans vs Buffalo Bills Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Tennessee Titans vs Buffalo Bills Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 19, 2022 NFL Games
Matchup |
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Minnesota Vikings vs Philadelphia Eagles |