Tennessee Titans vs Buffalo Bills Odds

The Titans will play the Bills on Monday, September 19th, 2022. The matchup takes place at Highmark Stadium. Watch this exciting Week 2 matchup at 7:15 pm EDT. Check local listings for coverage on ESPN, ESPN2.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Best Titans at Bills Odds


Best Point Spread Betting Odds
Underdog

Tennessee Titans
Favorite

Buffalo Bills
The Buffalo Bills have a -10 -110 point spread at BetRivers VA. They are the point spread favorite in this matchup. The Tennessee Titans have a +10 -110 point spread at BetRivers. The Tennessee Titans are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 47.5 points. Risk $112 to win $100. BetRivers has the best under line of 47.5 points. Risk $109 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Tennessee Titans
Favorite

Buffalo Bills
The Buffalo Bills are the -435 moneyline favorite. Risk $435 to win $100 on the Buffalo Bills at BetRivers. The Tennessee Titans are the +360 underdog at BetRivers. Risk $100 to win $360 on the Tennessee Titans. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Tennessee Titans vs Buffalo Bills NFL game on Monday, September 19th, 2022?

The Buffalo Bills are -10 -110 point spread favorites at BetRivers, while the Tennessee Titans are +10 -110 point spread underdogs at BetRivers.

What is the over-under total line for the Tennessee Titans vs Buffalo Bills NFL game on Monday, September 19th, 2022?

The best over line is 47.5 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 47.5 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.

What is the moneyline for the Tennessee Titans vs Buffalo Bills NFL game on Monday, September 19th, 2022?

The Buffalo Bills are the -435 moneyline favorite at BetRivers and the Tennessee Titans are the +360 moneyline underdog at BetRivers.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Titans
Bills
9/19/22 7:15pm EDT
+10 -110-10 -110
Bet $100 at BetRivers Virginia
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Underdog Tennessee Titans - Tennessee Titans bettors risk $100 to win $90.91 at -110 odds.

A +10 Tennessee Titans underdog bet wins if they lose by 9 or fewer, tie, or win outright. The bet pushes if they lose by 10. Your bet loses if they lose by 11 or more.

Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $90.91 at -110 odds.

A -10 Buffalo Bills favorite bet wins if they win by 11 or more. The bet pushes if they win by 10. Your bet loses if they win by 9 or fewer, tie, or lose outright.

Tennessee Titans at Buffalo Bills Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Titans
Bills
First Team To Score
9/19/22 7:15pm EDT
+128-177Bet
Titans
Bills
Tie
First to 15 Points
9/19/22 7:15pm EDT
+260-360+2800Bet
Titans
Bills
Tie
First to 20 Points
9/19/22 7:15pm EDT
+320-335+900Bet

Recent Meetings Since 2018

Recent Meetings Since 2018
WeekGameResultMargin
2022
Week 2
Titans vs Bills
Monday, September 19th, 2022
BUF 41, TEN 7
Highmark Stadium
Bills by 34
2021
Week 6
Bills vs Titans
Monday, October 18th, 2021
TEN 34, BUF 31
Nissan Stadium
Titans by 3
2020
Week 5
Bills vs Titans
Tuesday, October 13th, 2020
TEN 42, BUF 16
Nissan Stadium
Titans by 26
2019
Week 5
Bills vs Titans
Sunday, October 6th, 2019
BUF 14, TEN 7
Nissan Stadium
Bills by 7
2018
Week 5
Titans vs Bills
Sunday, October 7th, 2018
BUF 13, TEN 12
Highmark Stadium
Bills by 1

Team Standings

2022-2023 NFL Regular Season Standings - Tennessee Titans, Buffalo Bills
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz - Buffalo Bills13300.8134552867-1-06-2-04-2-00.6679-2-00.8187W5-0-0
Tennessee Titans71000.4122983593-5-04-5-03-3-00.5005-7-00.4177L0-5-0

Tennessee Titans & Buffalo Bills Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Tennessee Titans Futures Odds
2024-25 Tennessee Titans Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Titans
+15000
Bet
+15000
Bet
Buffalo Bills Futures Odds
2024-25 Buffalo Bills Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Bills
+1200
Bet
+1200
Bet

Tennessee Titans & Buffalo Bills Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Tennessee Titans vs Buffalo Bills NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Monday, September 19th, 2022 at 7:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Tennessee Titans vs Buffalo Bills Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Tennessee Titans vs Buffalo Bills Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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