San Francisco 49ers vs Jacksonville Jaguars NFL Betting Lines

Odds Preview 489

The 49ers will play the Jaguars on Sunday, November 21st, 2021. The matchup takes place at TIAA Bank Field. Watch this exciting week 11 matchup at 1:00 pm on FOX.

Best Underdog and Favorite Spread Bets
Underdog

Jacksonville Jaguars
Favorite

San Francisco 49ers
+6.5 -105 Sb3gen2 -6.5 -110 Sb3gen3
+6.5 -106 Sb3gen1 -6.5 -114 Sb3gen1
+6.5 -110 Sb3gen3 -6.5 -115 Sb3gen2
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Sunday. Sb3gen3 has the best favorite San Francisco 49ers spread at -6.5 points. Sb3gen2 has the best underdog Jacksonville Jaguars spread at +6.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
45.5o -107 Sb3gen1 45.5u -110 Sb3gen2
45.5o -110 Sb3gen2 45.5u -110 Sb3gen3
45.5o -110 Sb3gen3 45.5u -113 Sb3gen1
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 45.5 points laying $107 to win $100. Sb3gen2 has the best under line of 45.5 u -110.
Best Money Line Bets
Underdog

Jacksonville Jaguars
Favorite

San Francisco 49ers
+255 Sb3gen2 -300 Sb3gen1
+250 Sb3gen1 -300 Sb3gen3
+240 Sb3gen3 -310 Sb3gen2
Here are money lines for the outright winner. Favorite San Francisco 49ers has a minus value. Lay $300 at Sb3gen1 to win $100. Underdog Jacksonville Jaguars has a positive value. Risk $100 at Sb3gen2 to win $255.

San Francisco 49ers vs Jacksonville Jaguars Prop Bets

The following prop bets are available for this matchup.

Super Bowl Odds

Latest Super Bowl odds, if available, for each team. Review odds for other teams and learn the best NFL bets here.

San Francisco 49ers Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
San Francisco 49ers

Cached 2021-12-01 07:02:47
Jacksonville Jaguars Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Jacksonville Jaguars

Cached 2021-12-01 07:02:47

Team Stats

2021 San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 236 212
Total Offensive Yards 4016 3506
Total Rushing Yards 1440 1226
Total Passing Yards 2576 2280
Sacks 24 21
Field Goals 17 / 21 13 / 16
Touchdowns 33 30
Avg Time Of Possession 31:04 28:55
Turnover Ratio -4

2021 Jacksonville Jaguars Team Stats
Stat Jacksonville Jaguars Opponents
Total 1st Downs 203 229
Total Offensive Yards 3551 3963
Total Rushing Yards 1266 1274
Total Passing Yards 2285 2689
Sacks 19 20
Field Goals 10 / 16 20 / 23
Touchdowns 21 32
Avg Time Of Possession 27:00 32:59
Turnover Ratio -13


Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
San Francisco 49ers
5-4-0 1-3-0 6 5 0 0.545 2-4-0 4-1-0 4-1-0
Jacksonville Jaguars
2-5-0 0-3-0 2 9 0 0.182 2-5-0 0-4-0 1-4-0

2021 San Francisco 49ers Games & Results

Bye Week: 6
WeekMatchupDate & Time
1 49ers vs
Lions
SF 41, DET 33
09/12/2021
2 49ers vs
Eagles
SF 17, PHI 11
09/19/2021
3 Packers vs
49ers
GB 30, SF 28
09/26/2021
4 Seahawks vs
49ers
SEA 28, SF 21
10/03/2021
5 49ers vs
Cardinals
ARI 17, SF 10
10/10/2021
6San Francisco 49ers ByeN/A
7 Colts vs
49ers
IND 30, SF 18
10/24/2021
8 49ers vs
Bears
SF 33, CHI 22
10/31/2021
9 Cardinals vs
49ers
ARI 31, SF 17
11/07/2021
10 Rams vs
49ers
SF 31, LAR 10
11/15/2021
11 49ers vs
Jaguars
SF 30, JAX 10
11/21/2021
12 Vikings vs
49ers
SF 34, MIN 26
11/28/2021
13 49ers vs
Seahawks
12/05/2021
8:20PM
14 49ers vs
Bengals
12/12/2021
1:00PM
15 Falcons vs
49ers
12/19/2021
4:05PM
16 49ers vs
Titans
12/23/2021
8:20PM
17 Texans vs
49ers
01/02/2022
4:05PM

2021 Jacksonville Jaguars Games & Results

Bye Week: 7
WeekMatchupDate & Time
1 Jaguars vs
Texans
HOU 37, JAX 21
09/12/2021
2 Broncos vs
Jaguars
DEN 23, JAX 13
09/19/2021
3 Cardinals vs
Jaguars
ARI 31, JAX 19
09/26/2021
4 Jaguars vs
Bengals
CIN 24, JAX 21
09/30/2021
5 Titans vs
Jaguars
TEN 37, JAX 19
10/10/2021
6 Dolphins vs
Jaguars
JAX 23, MIA 20
10/17/2021
7Jacksonville Jaguars ByeN/A
8 Jaguars vs
Seahawks
SEA 31, JAX 7
10/31/2021
9 Bills vs
Jaguars
JAX 9, BUF 6
11/07/2021
10 Jaguars vs
Colts
IND 23, JAX 17
11/14/2021
11 49ers vs
Jaguars
SF 30, JAX 10
11/21/2021
12 Falcons vs
Jaguars
ATL 21, JAX 14
11/28/2021
13 Jaguars vs
Rams
12/05/2021
4:25PM
14 Jaguars vs
Titans
12/12/2021
1:00PM
15 Texans vs
Jaguars
12/19/2021
1:00PM
16 Jaguars vs
Jets
12/26/2021
1:00PM
17 Jaguars vs
Patriots
01/02/2022
1:00PM

Other 2021 Week 11 Matchups

MatchupDate & Time
Patriots vs
Falcons
NE 25, ATL 0
11/18/2021
Colts vs
Bills
IND 41, BUF 15
11/21/2021
Ravens vs
Bears
BAL 16, CHI 13
11/21/2021
Lions vs
Browns
CLE 13, DET 10
11/21/2021
Texans vs
Titans
HOU 22, TEN 13
11/21/2021
Packers vs
Vikings
MIN 34, GB 31
11/21/2021
Dolphins vs
Jets
MIA 24, NYJ 17
11/21/2021
Saints vs
Eagles
PHI 40, NO 29
11/21/2021
TBD vs
Panthers
WSH 27, CAR 21
11/21/2021
49ers vs
Jaguars
SF 30, JAX 10
11/21/2021
Bengals vs
Raiders
CIN 32, LV 13
11/21/2021
Cowboys vs
Chiefs
KC 19, DAL 9
11/21/2021
Cardinals vs
Seahawks
ARI 23, SEA 13
11/21/2021
Steelers vs
Chargers
LAC 41, PIT 37
11/21/2021
Giants vs
Buccaneers
TB 30, NYG 10
11/22/2021