The Falcons will play the Cardinals on Sunday, December 21st, 2025. The matchup takes place at State Farm Stadium. Watch this exciting Week 16 matchup at 4:05 pm EST. Check local listings for coverage on FOX.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
It's now Week 16, as the 2025-26 NFL regular season is coming to a close. This week's action includes a matchup between the Atlanta Falcons and Arizona Cardinals. They'll play on Sunday, December 21st, 2025 at State Farm Stadium, in a game that may affect this season's playoff picture. We've highlighted each team's key performance stats below. Take note of the following as you handicap this matchup.
- SportsBetting3.com Power Rankings - Now Week 16 of the 2025-26 NFL regular season, the Atlanta Falcons have a 87.33 power ranking based on our formula. Their opponent, the Arizona Cardinals, currently possess a 84.33 power ranking.
- Away Atlanta Falcons - With the season coming to a close, the Atlanta Falcons have a 3-5-0 record as an away team, ranking them 4th in the league for away team wins.
- Home Arizona Cardinals - The Arizona Cardinals come to this Week 16 game with a 1-6-0 record as a home team. They rank 7th in the league for home team wins as the 2025-26 regular season wraps up.
- Points Scored - The Atlanta Falcons currently rank 25th (281) headed into Week 16, with the Arizona Cardinals ranked 21st (302) for points scored to date.
- Points Against - As the regular season winds down, the Atlanta Falcons rank 11th (341) for points score against them. Note that the Arizona Cardinals now rank 6th (388) for points scored against.
- Team Records - The final games of the season will determine who heads to the playoffs. Heading into Week 16, the Atlanta Falcons have a 5-9-0 record, with the Arizona Cardinals at 3-11-0 for the 2025-26 NFL regular season.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye! The Atlanta Falcons face the Arizona Cardinals in a pivotal Week 16 showdown.
The NFL regular season be winding down, and this game could shake up the playoff picture.
The Falcons be 5-9-0, while the Cardinals be 3-11-0. Place a bet at BetRivers or BetMGM. Be sure to look at this matchup's prop bets below. We've compared odds from our partner sportsbooks.
Best Falcons at Cardinals Odds
| Underdog Arizona Cardinals | Favorite Atlanta Falcons |
|---|---|
| Over | Under |
|---|---|
| Underdog Arizona Cardinals | Favorite Atlanta Falcons |
|---|---|
Matchup Odds FAQs
The Atlanta Falcons are -2.5 -110 point spread favorites at BetMGM, while the Arizona Cardinals are +2.5 -110 point spread underdogs at BetMGM.
The best over line is 47.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 47.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Atlanta Falcons are the -140 moneyline favorite at BetMGM and the Arizona Cardinals are the +118 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Falcons
Cardinals
12/21/25 4:05pm EST | -2.5 -110+2.5 -110 |
Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $90.91 at -110 odds.
A +2.5 Arizona Cardinals underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.
Favorite Atlanta Falcons - Atlanta Falcons bettors risk $100 to win $90.91 at -110 odds.
A -2.5 Atlanta Falcons favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.
Atlanta Falcons at Arizona Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Falcons
Cardinals
No Touchdown
To Score 1st Touchdown
12/21/25 4:05pm EST | -130-102+10000Bet |
Falcons
Cardinals
Game to Overtime
12/21/25 4:05pm EST | Yes +675No -2000Bet |
Falcons
Cardinals
Safety to be Scored
12/21/25 4:05pm EST | Yes +1000No -3000Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2023 Week 10 | Falcons vs Cardinals Sunday, November 12th, 2023 | ARI 25, ATL 23 State Farm Stadium | Cardinals by 2 |
| 2022 Week 17 | Cardinals vs Falcons Sunday, January 1st, 2023 | ATL 20, ARI 19 Mercedes-Benz Stadium | Falcons by 1 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Atlanta Falcons | 5 | 9 | 0 | 0.357 | 281 | 341 | 2-4-0 | 3-5-0 | 2-3-0 | 0.400 | 4-5-0 | 0.444 | 1W | 2-3-0 |
| Arizona Cardinals | 3 | 11 | 0 | 0.214 | 302 | 388 | 1-6-0 | 2-5-0 | 0-5-0 | 0.000 | 3-7-0 | 0.300 | 6L | 0-5-0 |
Atlanta Falcons & Arizona Cardinals Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Atlanta Falcons Futures OddsNo Super Bowl TM Atlanta Falcons YR: futures available
Arizona Cardinals Futures OddsNo Super Bowl TM Arizona Cardinals YR: futures available
Atlanta Falcons & Arizona Cardinals Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Atlanta Falcons vs Arizona Cardinals NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, December 21st, 2025 at 4:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Atlanta Falcons vs Arizona Cardinals Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Atlanta Falcons vs Arizona Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other December 21, 2025 NFL Games
- Tampa Bay Buccaneers vs Carolina Panthers - 12/21/25 1:00pm EST
- Kansas City Chiefs vs Tennessee Titans - 12/21/25 1:00pm EST
- Minnesota Vikings vs New York Giants - 12/21/25 1:00pm EST
- New York Jets vs New Orleans Saints - 12/21/25 1:00pm EST
- Cincinnati Bengals vs Miami Dolphins - 12/21/25 1:00pm EST
- Los Angeles Chargers vs Dallas Cowboys - 12/21/25 1:00pm EST
- Buffalo Bills vs Cleveland Browns - 12/21/25 1:00pm EST
- Jacksonville Jaguars vs Denver Broncos - 12/21/25 4:05pm EST
- Pittsburgh Steelers vs Detroit Lions - 12/21/25 4:25pm EST
- Las Vegas Raiders vs Houston Texans - 12/21/25 4:25pm EST
- New England Patriots vs Baltimore Ravens - 12/21/25 8:20pm EST