The Buccaneers will play the Bills on Sunday, November 16th, 2025. The matchup takes place at Highmark Stadium. Watch this exciting Week 11 matchup at 1:00 pm EST. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.

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Matchup Stats
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Key Matchup Stats

Rolling into Week 11, the Tampa Bay Buccaneers and Buffalo Bills will matchup on Sunday, November 16th, 2025 at Highmark Stadium for an important mid-season game. We've compiled some key performance stats below to help you handicap this matchup. Now that the 2025-26 NFL regular season is half over, teams need to sharpen their performance with an eye for the January playoffs.

SportsBetting3.com Power Rankings - As of Week 11 of the 2025-26 season, the Tampa Bay Buccaneers have a power ranking of 93.33. Our formula has the Buffalo Bills at a 94.67 power ranking.
Away Tampa Bay Buccaneers - With the season now half over, the Tampa Bay Buccaneers have a 4-1-0 record as an away team, ranking them 2nd in the league for away team wins.
Home Buffalo Bills - The Buffalo Bills start this Week 11 matchup with a 4-1-0 record as a home team. They rank 3rd in the league for home team wins so far in the 2025-26 regular season.
Points Scored - The Tampa Bay Buccaneers currently rank 13th (220) looking at Week 11, with the Buffalo Bills ranked 7th (248) for points scored to date.
Points Against - The Tampa Bay Buccaneers stand 18th (206) now halfway through the regular season for points against. Meanwhile the Buffalo Bills currently rank 21st (197) for points against.
Team Records - The second half of the season is make or break. Heading into Week 11, the Tampa Bay Buccaneers have a 6-3-0 record, with the Buffalo Bills at 6-3-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Arrr, ye scurvy dogs! The Buccaneers be facin' the Bills in a crucial Week 11 battle.

The season be halfway through, and every win be crucial for makin' the playoffs.

The game be happenin' at Highmark Stadium, in the heart of Buffalo's fierce culture. Buccaneers be rankin' at 93.33, while the Bills be at 94.67. I recommend betting on this game at BetRivers, or BetMGM, review this matchup's prop bets below, look at the odds from our partner sportsbooks.

Best Buccaneers at Bills Odds

**Best Point Spread Betting Odds**
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**Best Total Betting Odds**
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**Best Moneyline Betting Odds**
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NFL Odds Example

NFL Odds and Outcomes Explained
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Tampa Bay Buccaneers at Buffalo Bills Prop Bets

NFL Prop Bets
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	Bet
Buccaneers Bills 11/16/25 1:00pm EST	Pending

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 11	Buccaneers vs Bills Sunday, November 16th, 2025	BUF 44, TB 32 Highmark Stadium	Bills by 12
2025 Preseason Week 3	Bills vs Buccaneers Saturday, August 23rd, 2025	BUF 23, TB 19 Raymond James Stadium	Bills by 4
2023 Week 8	Buccaneers vs Bills Thursday, October 26th, 2023	BUF 24, TB 18 Highmark Stadium	Bills by 6
2021 Week 14	Bills vs Buccaneers Sunday, December 12th, 2021	TB 33, BUF 27 (OT) Raymond James Stadium	Buccaneers by 6

Team Standings

2025-2026 NFL Regular Season Standings - Tampa Bay Buccaneers, Buffalo Bills
Team	W	L	T	Pct	PF	PA	Home	Away	Div	Div%	Conf	Conf%	Strk	L5
xy - Buffalo Bills	12	5	0	0.706	481	365	7-2-0	5-3-0	4-2-0	0.667	9-3-0	0.750	1W	4-1-0
Tampa Bay Buccaneers	8	9	0	0.471	380	411	4-4-0	4-5-0	3-3-0	0.500	6-6-0	0.500	1W	1-4-0

Tampa Bay Buccaneers & Buffalo Bills Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Tampa Bay Buccaneers Futures Odds

No Super Bowl TM Tampa Bay Buccaneers YR: futures available

Buffalo Bills Futures Odds

No Super Bowl TM Buffalo Bills YR: futures available

Tampa Bay Buccaneers & Buffalo Bills Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Tampa Bay Buccaneers vs Buffalo Bills NFL Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 16th, 2025 at 1:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's NFL page, look for the Tampa Bay Buccaneers vs Buffalo Bills Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Tampa Bay Buccaneers vs Buffalo Bills Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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