San Francisco 49ers vs Arizona Cardinals Odds

The 49ers will play the Cardinals on Sunday, December 17th, 2023. The matchup takes place at State Farm Stadium. Watch this exciting Week 15 matchup at 4:05 pm EST. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

It's now Week 15, as the 2023-24 NFL regular season is coming to a close. This week's action includes a matchup between the San Francisco 49ers and Arizona Cardinals. They'll play on Sunday, December 17th, 2023 at State Farm Stadium, in a game that may affect this season's playoff picture. We've highlighted each team's key performance stats below. Take note of the following as you handicap this matchup.

  • SportsBetting3.com Power Rankings - Now Week 15 of the 2023-24 NFL regular season, the San Francisco 49ers have a 99.67 power ranking based on our formula. Their opponent, the Arizona Cardinals, currently possess a 87.00 power ranking.
  • Away San Francisco 49ers - With the season coming to a close, the San Francisco 49ers have a 5-2-0 record as an away team, ranking them 1st in the league for away team wins.
  • Home Arizona Cardinals - The Arizona Cardinals come to this Week 15 game with a 2-4-0 record as a home team. They rank 6th in the league for home team wins as the 2023-24 regular season wraps up.
  • Points Scored - The San Francisco 49ers currently rank 3rd (380) headed into Week 15, with the Arizona Cardinals ranked 23rd (230) for points scored to date.
  • Points Against - As the regular season winds down, the San Francisco 49ers rank 29th (205) for points score against them. Note that the Arizona Cardinals now rank 3rd (331) for points scored against.
  • Team Records - The final games of the season will determine who heads to the playoffs. Heading into Week 15, the San Francisco 49ers have a 10-3-0 record, with the Arizona Cardinals at 3-10-0 for the 2023-24 NFL regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, me hearties! Avast ye! It be time for some pigskin plunderin' as the San Francisco 49ers set sail to face the scurvy Arizona Cardinals on Sunday, December 17th, 2023. This be an important Week 15 battle as the NFL regular season be nearin' its end. Aye, the outcome o' this clash may well shape the playoff picture, me mateys!

The mighty San Francisco 49ers be sportin' a glorious 10-3-0 record, while them Cardinals be strugglin' at 3-10-0. The 49ers be dominatin' the NFC West Division with a perfect 4-0-0 standing, while them Cardinals be a woeful 0-4-0. It be clear as the open sea that the 49ers be the favorites in this match.

This here skirmish be takin' place at the grand State Farm Stadium, and it promises to be a battle for the ages. According to the SportsBetting3.com NFL Power Rankings, the 49ers be holdin' a mighty 99.67 rating, while them Cardinals be laggin' behind at a mere 87.00. If ye be wantin' to place a bet at BetRivers, BetWay, or BetMGM, be sure to look at this matchup's prop bets below!

So, me hearties, with the NFL regular season nearin' its end, this be a crucial clash. The San Francisco 49ers, led by their mighty crew, be seekin' to solidify their playoff hopes. The Arizona Cardinals, aye, they be fightin' for pride and honor. We've compared odds from our partner sportsbooks, so place yer bets and prepare for an epic showdown on the gridiron!

Best 49ers at Cardinals Odds


Best Point Spread Betting Odds
Underdog

Arizona Cardinals
Favorite

San Francisco 49ers
The San Francisco 49ers have a -11.5 -110 point spread at BetMGM VA. They are the point spread favorite in this matchup. The Arizona Cardinals have a +12 -110 point spread at BetRivers VA. The Arizona Cardinals are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 48.5 points. Risk $109 to win $100. BetMGM has the best under line of 48.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

San Francisco 49ers
Favorite

San Francisco 49ers
The San Francisco 49ers are the -750 moneyline favorite. Risk $750 to win $100 on the San Francisco 49ers at BetMGM. The San Francisco 49ers are the -750 underdog at BetMGM. Risk $750 to win $100 on the San Francisco 49ers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the San Francisco 49ers vs Arizona Cardinals NFL game on Sunday, December 17th, 2023?

The San Francisco 49ers are -11.5 -110 point spread favorites at BetMGM, while the Arizona Cardinals are +12 -110 point spread underdogs at BetRivers.

What is the over-under total line for the San Francisco 49ers vs Arizona Cardinals NFL game on Sunday, December 17th, 2023?

The best over line is 48.5 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 48.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the San Francisco 49ers vs Arizona Cardinals NFL game on Sunday, December 17th, 2023?

The San Francisco 49ers are the -750 moneyline favorite at BetMGM and the San Francisco 49ers are the -750 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
49ers
Cardinals
12/17/23 4:05pm EST
-12 -110+12 -110
Bet $100 at BetRivers Virginia
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Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $90.91 at -110 odds.

A +12 Arizona Cardinals underdog bet wins if they lose by 11 or fewer, tie, or win outright. The bet pushes if they lose by 12. Your bet loses if they lose by 13 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.

A -12 San Francisco 49ers favorite bet wins if they win by 13 or more. The bet pushes if they win by 12. Your bet loses if they win by 11 or fewer, tie, or lose outright.

San Francisco 49ers at Arizona Cardinals Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
49ers
Cardinals
First Team To Score
12/17/23 4:05pm EST
-195+148Bet
49ers
Cardinals
To Score 1st Touchdown
12/17/23 4:05pm EST
-250+188Bet
49ers
Cardinals
Tie
First to 15 Points
12/17/23 4:05pm EST
-480+285+5000Bet
49ers
Cardinals
Tie
First to 20 Points
12/17/23 4:05pm EST
-500+400+1050Bet
BetRivers Sports Betting BetRivers
49ers
Cardinals
Safety to be Scored
12/17/23 4:05pm EST
Yes +1500No -5000Bet
Cardinals
Team Total Points
SF at ARI
12/17/23 4:05pm EST
17.5 o -10417.5 u -118Bet
49ers
Team Total Points
SF at ARI
12/17/23 4:05pm EST
30.5 o -11830.5 u -103Bet
Brock Purdy
Total Touchdown Passes
SF at ARI
12/17/23 4:05pm EST
1.5 o -1861.5 u +140Bet
BetRivers Sports Betting BetRivers
Brock Purdy
Total Passing Yards
SF at ARI
12/17/23 4:05pm EST
255.5 o -113255.5 u -115Bet
Jake Moody
Total Kicking Points
SF at ARI
12/17/23 4:05pm EST
8.5 o +1038.5 u -134Bet
Kyler Murray
Total Passing Yards
SF at ARI
12/17/23 4:05pm EST
211.5 o -115211.5 u -113Bet
Kyler Murray
Total Touchdown Passes
SF at ARI
12/17/23 4:05pm EST
0.5 o -2750.5 u +195Bet
BetRivers Sports Betting BetRivers
Matt Prater
Total Kicking Points
SF at ARI
12/17/23 4:05pm EST
4.5 o -1414.5 u +108Bet

Recent Meetings Since 2019

Recent Meetings Since 2019
WeekGameResultMargin
2023
Week 15
49ers vs Cardinals
Sunday, December 17th, 2023
SF 45, ARI 29
State Farm Stadium
49ers by 16
2023
Week 4
Cardinals vs 49ers
Sunday, October 1st, 2023
SF 35, ARI 16
Levi's Stadium
49ers by 19
2022
Week 18
Cardinals vs 49ers
Sunday, January 8th, 2023
SF 38, ARI 13
Levi's Stadium
49ers by 25
2022
Week 11
49ers vs Cardinals
Monday, November 21st, 2022
SF 38, ARI 10
Estadio Azteca
49ers by 28
2021
Week 9
Cardinals vs 49ers
Sunday, November 7th, 2021
ARI 31, SF 17
Levi's Stadium
Cardinals by 14
2021
Week 5
49ers vs Cardinals
Sunday, October 10th, 2021
ARI 17, SF 10
State Farm Stadium
Cardinals by 7
2020
Week 16
49ers vs Cardinals
Saturday, December 26th, 2020
SF 20, ARI 12
State Farm Stadium
49ers by 8
2020
Week 1
Cardinals vs 49ers
Sunday, September 13th, 2020
ARI 24, SF 20
Levi's Stadium
Cardinals by 4
2019
Week 11
Cardinals vs 49ers
Sunday, November 17th, 2019
SF 36, ARI 26
Levi's Stadium
49ers by 10
2019
Week 9
49ers vs Cardinals
Thursday, October 31st, 2019
SF 28, ARI 25
State Farm Stadium
49ers by 3

Team Standings

2023-2024 NFL Regular Season Standings - San Francisco 49ers, Arizona Cardinals
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz* - San Francisco 49ers12500.7064912985-3-07-2-05-1-00.83310-2-00.8331L3-2-0
Arizona Cardinals41300.2353304552-6-02-7-00-6-00.0003-9-00.2501L2-3-0

San Francisco 49ers & Arizona Cardinals Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

San Francisco 49ers Futures Odds
2024-25 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
49ers
+600
Bet
+600
Bet
Arizona Cardinals Futures Odds
2024-25 Arizona Cardinals Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Cardinals
+10000
Bet
+10000
Bet

San Francisco 49ers & Arizona Cardinals Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco 49ers vs Arizona Cardinals NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, December 17th, 2023 at 4:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Arizona Cardinals Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Arizona Cardinals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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