The Titans will play the Cardinals on Sunday, October 5th, 2025. The matchup takes place at State Farm Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The Tennessee Titans and Arizona Cardinals will take the field at State Farm Stadium for a key Week 5 matchup on Sunday, October 5th, 2025. Have a look at each team's key performance stats below as they continue to make their way through the 2025-26 NFL regular season.
- SportsBetting3.com Power Rankings - Heading into Week 5 of the 2025-26 season, the Tennessee Titans have a power ranking of 85.67. Our calculations have the Arizona Cardinals at a 93.00 power ranking.
- Away Tennessee Titans - Now in the middle of the season, the Tennessee Titans have a 0-2-0 record as an away team, ranking them 3rd in the league for away team wins.
- Home Arizona Cardinals - The Arizona Cardinals come to this Week 5 matchup with a 1-1-0 record as a home team. They rank 3rd in the league for home team wins so far this season.
- Points Scored - The Tennessee Titans currently rank 28th (51) on the edge of Week 5, with the Arizona Cardinals ranked 16th (82) for points scored to date.
- Points Against - The Tennessee Titans stand 4th (120) in the middle weeks of the regular season for points against. As for the Arizona Cardinals, they currently rank 23rd (74) for points against.
- Team Records - Standings become more important now more than ever. Approaching Week 5, the Tennessee Titans have a 0-4-0 record, with the Arizona Cardinals at 2-2-0 for the 2025-26 regular season.
Captain Shady Lines
A broken compass is right at least twice a day.

Avast ye scallywags! The Tennessee Titans be facing the Arizona Cardinals in a crucial Week 5 showdown on October 5th, 2025. The Titans be 0-4-0 while the Cardinals be 2-2-0. Every game be important in the middle of the season!
This clash be happenin' at State Farm Stadium in a city rich in culture and history. The atmosphere be electric as these two teams battle for supremacy on the gridiron.
According to the SportsBetting3.com NFL Power Rankings, the Titans be rated at 85.67 while the Cardinals be at 93.00. It be a close match-up, so bet this game at BetMGM or our preferred sports betting partner BetRivers. Look at this game's prop bets and compare odds from partner sports betting sites to make yer wager! Arrr!
Best Titans at Cardinals Odds
| Underdog Tennessee Titans | Favorite Arizona Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog Tennessee Titans | Favorite Arizona Cardinals |
|---|---|
Matchup Odds FAQs
The Arizona Cardinals are -7.5 -105 point spread favorites at BetMGM, while the Tennessee Titans are +7.5 -115 point spread underdogs at BetMGM.
The best over line is 41 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 41 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Arizona Cardinals are the -425 moneyline favorite at BetMGM and the Tennessee Titans are the +325 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
Bet |
|---|---|
Titans
Cardinals
10/05/25 4:05pm EDT | +7.5 -115-7.5 -105 |
Underdog Tennessee Titans - Tennessee Titans bettors risk $100 to win $86.96 at -115 odds.
A +7.5 Tennessee Titans underdog bet wins if they lose by 7 or fewer, tie, or win outright. Your bet loses if they lose by 8 or more.
Favorite Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $95.24 at -105 odds.
A -7.5 Arizona Cardinals favorite bet wins if they win by 8 or more. Your bet loses if they win by 7 or fewer, tie, or lose outright.
Tennessee Titans at Arizona Cardinals Prop Bets
Bet |
|
|---|---|
Titans
Cardinals
First Team To Score
10/05/25 4:05pm EDT | +125-160Bet |
Titans
Cardinals
No Touchdown
To Score 1st Touchdown
10/05/25 4:05pm EDT | +154-200+6600Bet |
Titans
Cardinals
Game to Overtime
10/05/25 4:05pm EDT | Yes +825No -3000Bet |
Titans
Cardinals
Safety to be Scored
10/05/25 4:05pm EDT | Yes +1000No -3000Bet |
Cam Ward
Interceptions Thrown
TEN at ARI 10/05/25 4:05pm EDT | 0.5 o -1300.5 u -105Bet |
Kyler Murray
Interceptions Thrown
TEN at ARI 10/05/25 4:05pm EDT | 0.5 o +1250.5 u -165Bet |
Cam Ward
Longest Passing Completion
TEN at ARI 10/05/25 4:05pm EDT | 30.5 o -10530.5 u -125Bet |
Kyler Murray
Longest Passing Completion
TEN at ARI 10/05/25 4:05pm EDT | 33.5 o -11833.5 u -110Bet |
Chad Ryland
Total Kicking Points
TEN at ARI 10/05/25 4:05pm EDT | 7.5 o -1257.5 u -105Bet |
Joey Slye
Total Kicking Points
TEN at ARI 10/05/25 4:05pm EDT | 6.5 o +1056.5 u -140Bet |
Cam Ward
Total Pass Completions
TEN at ARI 10/05/25 4:05pm EDT | 17.5 o -12017.5 u -110Bet |
Kyler Murray
Total Pass Completions
TEN at ARI 10/05/25 4:05pm EDT | 20.5 o -13520.5 u +100Bet |
Cam Ward
Total Passing Yards
TEN at ARI 10/05/25 4:05pm EDT | 178.5 o -115178.5 u -115Bet |
Kyler Murray
Total Passing Yards
TEN at ARI 10/05/25 4:05pm EDT | 216.5 o -115216.5 u -115Bet |
Cam Ward
Total Touchdown Passes
TEN at ARI 10/05/25 4:05pm EDT | 0.5 o -1750.5 u +130Bet |
Kyler Murray
Total Touchdown Passes
TEN at ARI 10/05/25 4:05pm EDT | 1.5 o +1051.5 u -140Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 5 | Titans vs Cardinals Sunday, October 5th, 2025 | TEN 22, ARI 21 State Farm Stadium | Titans by 1 |
| 2022 Preseason Week 3 | Cardinals vs Titans Saturday, August 27th, 2022 | TEN 26, ARI 23 Nissan Stadium | Titans by 3 |
| 2021 Week 1 | Cardinals vs Titans Sunday, September 12th, 2021 | ARI 38, TEN 13 Nissan Stadium | Cardinals by 25 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arizona Cardinals | 2 | 5 | 0 | 0.286 | 153 | 154 | 1-3-0 | 1-2-0 | 0-2-0 | 0.000 | 2-3-0 | 0.400 | 5L | 0-5-0 |
| Tennessee Titans | 1 | 7 | 0 | 0.125 | 110 | 230 | 0-3-0 | 1-4-0 | 0-3-0 | 0.000 | 0-6-0 | 0.000 | 3L | 1-4-0 |
Tennessee Titans & Arizona Cardinals Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Tennessee Titans Futures Odds|
Team | |
|---|---|
| Titans | +100000 Bet |
|
Team | |
|---|---|
| Cardinals | +50000 Bet |
Tennessee Titans & Arizona Cardinals Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Tennessee Titans vs Arizona Cardinals NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 5th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Tennessee Titans vs Arizona Cardinals Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Tennessee Titans vs Arizona Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other October 5, 2025 NFL Games
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- Houston Texans vs Baltimore Ravens
- Denver Broncos vs Philadelphia Eagles
- Dallas Cowboys vs New York Jets
- Las Vegas Raiders vs Indianapolis Colts
- Miami Dolphins vs Carolina Panthers
- Tampa Bay Buccaneers vs Seattle Seahawks
- Detroit Lions vs Cincinnati Bengals
- Washington Commanders vs Los Angeles Chargers
- New England Patriots vs Buffalo Bills