Tennessee Titans vs Arizona Cardinals Odds

The Titans will play the Cardinals on Sunday, October 5th, 2025. The matchup takes place at State Farm Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The Tennessee Titans and Arizona Cardinals will take the field at State Farm Stadium for a key Week 5 matchup on Sunday, October 5th, 2025. Have a look at each team's key performance stats below as they continue to make their way through the 2025-26 NFL regular season.

  • SportsBetting3.com Power Rankings - Heading into Week 5 of the 2025-26 season, the Tennessee Titans have a power ranking of 85.67. Our calculations have the Arizona Cardinals at a 93.00 power ranking.
  • Away Tennessee Titans - Now in the middle of the season, the Tennessee Titans have a 0-2-0 record as an away team, ranking them 3rd in the league for away team wins.
  • Home Arizona Cardinals - The Arizona Cardinals come to this Week 5 matchup with a 1-1-0 record as a home team. They rank 3rd in the league for home team wins so far this season.
  • Points Scored - The Tennessee Titans currently rank 28th (51) on the edge of Week 5, with the Arizona Cardinals ranked 16th (82) for points scored to date.
  • Points Against - The Tennessee Titans stand 4th (120) in the middle weeks of the regular season for points against. As for the Arizona Cardinals, they currently rank 23rd (74) for points against.
  • Team Records - Standings become more important now more than ever. Approaching Week 5, the Tennessee Titans have a 0-4-0 record, with the Arizona Cardinals at 2-2-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Tennessee Titans be facing the Arizona Cardinals in a crucial Week 5 showdown on October 5th, 2025. The Titans be 0-4-0 while the Cardinals be 2-2-0. Every game be important in the middle of the season!

This clash be happenin' at State Farm Stadium in a city rich in culture and history. The atmosphere be electric as these two teams battle for supremacy on the gridiron.

According to the SportsBetting3.com NFL Power Rankings, the Titans be rated at 85.67 while the Cardinals be at 93.00. It be a close match-up, so bet this game at BetMGM or our preferred sports betting partner BetRivers. Look at this game's prop bets and compare odds from partner sports betting sites to make yer wager! Arrr!

Best Titans at Cardinals Odds


Best Point Spread Betting Odds
Underdog

Tennessee Titans
Favorite

Arizona Cardinals
The Arizona Cardinals have a -7.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Tennessee Titans have a +7.5 -115 point spread at BetMGM OH. The Tennessee Titans are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 41 points. Risk $110 to win $100. BetMGM has the best under line of 41 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Tennessee Titans
Favorite

Arizona Cardinals
The Arizona Cardinals are the -425 moneyline favorite. Risk $425 to win $100 on the Arizona Cardinals at BetMGM. The Tennessee Titans are the +325 underdog at BetMGM. Risk $100 to win $325 on the Tennessee Titans. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Tennessee Titans vs Arizona Cardinals NFL game on Sunday, October 5th, 2025?

The Arizona Cardinals are -7.5 -105 point spread favorites at BetMGM, while the Tennessee Titans are +7.5 -115 point spread underdogs at BetMGM.

What is the over-under total line for the Tennessee Titans vs Arizona Cardinals NFL game on Sunday, October 5th, 2025?

The best over line is 41 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 41 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Tennessee Titans vs Arizona Cardinals NFL game on Sunday, October 5th, 2025?

The Arizona Cardinals are the -425 moneyline favorite at BetMGM and the Tennessee Titans are the +325 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Titans
Cardinals
10/05/25 4:05pm EDT
+7.5 -115-7.5 -105
Bet $100 at BetMGM Ohio
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Underdog Tennessee Titans - Tennessee Titans bettors risk $100 to win $86.96 at -115 odds.

A +7.5 Tennessee Titans underdog bet wins if they lose by 7 or fewer, tie, or win outright. Your bet loses if they lose by 8 or more.

Favorite Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $95.24 at -105 odds.

A -7.5 Arizona Cardinals favorite bet wins if they win by 8 or more. Your bet loses if they win by 7 or fewer, tie, or lose outright.

Tennessee Titans at Arizona Cardinals Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Titans
Cardinals
First Team To Score
10/05/25 4:05pm EDT
+125-160Bet
Titans
Cardinals
No Touchdown
To Score 1st Touchdown
10/05/25 4:05pm EDT
+154-200+6600Bet
Titans
Cardinals
Game to Overtime
10/05/25 4:05pm EDT
Yes +825No -3000Bet
Titans
Cardinals
Safety to be Scored
10/05/25 4:05pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Cam Ward
Interceptions Thrown
TEN at ARI
10/05/25 4:05pm EDT
0.5 o -1300.5 u -105Bet
Kyler Murray
Interceptions Thrown
TEN at ARI
10/05/25 4:05pm EDT
0.5 o +1250.5 u -165Bet
Cam Ward
Longest Passing Completion
TEN at ARI
10/05/25 4:05pm EDT
30.5 o -10530.5 u -125Bet
Kyler Murray
Longest Passing Completion
TEN at ARI
10/05/25 4:05pm EDT
33.5 o -11833.5 u -110Bet
BetMGM Sports Betting BetMGM
Chad Ryland
Total Kicking Points
TEN at ARI
10/05/25 4:05pm EDT
7.5 o -1257.5 u -105Bet
Joey Slye
Total Kicking Points
TEN at ARI
10/05/25 4:05pm EDT
6.5 o +1056.5 u -140Bet
Cam Ward
Total Pass Completions
TEN at ARI
10/05/25 4:05pm EDT
17.5 o -12017.5 u -110Bet
Kyler Murray
Total Pass Completions
TEN at ARI
10/05/25 4:05pm EDT
20.5 o -13520.5 u +100Bet
BetMGM Sports Betting BetMGM
Cam Ward
Total Passing Yards
TEN at ARI
10/05/25 4:05pm EDT
178.5 o -115178.5 u -115Bet
Kyler Murray
Total Passing Yards
TEN at ARI
10/05/25 4:05pm EDT
216.5 o -115216.5 u -115Bet
Cam Ward
Total Touchdown Passes
TEN at ARI
10/05/25 4:05pm EDT
0.5 o -1750.5 u +130Bet
Kyler Murray
Total Touchdown Passes
TEN at ARI
10/05/25 4:05pm EDT
1.5 o +1051.5 u -140Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 5
Titans vs Cardinals
Sunday, October 5th, 2025
TEN 22, ARI 21
State Farm Stadium
Titans by 1
2022
Preseason Week 3
Cardinals vs Titans
Saturday, August 27th, 2022
TEN 26, ARI 23
Nissan Stadium
Titans by 3
2021
Week 1
Cardinals vs Titans
Sunday, September 12th, 2021
ARI 38, TEN 13
Nissan Stadium
Cardinals by 25

Team Standings

2025-2026 NFL Regular Season Standings - Tennessee Titans, Arizona Cardinals
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Arizona Cardinals2500.2861531541-3-01-2-00-2-00.0002-3-00.4005L0-5-0
Tennessee Titans1700.1251102300-3-01-4-00-3-00.0000-6-00.0003L1-4-0

Tennessee Titans & Arizona Cardinals Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Tennessee Titans Futures Odds
2025-26 Tennessee Titans Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Titans
+100000
Bet
Arizona Cardinals Futures Odds
2025-26 Arizona Cardinals Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+50000
Bet

Tennessee Titans & Arizona Cardinals Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Tennessee Titans vs Arizona Cardinals NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 5th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Tennessee Titans vs Arizona Cardinals Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Tennessee Titans vs Arizona Cardinals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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