National Football League Week One Lines And Notes

The National Football League finally makes its glorious return with a full slate of games. The start of an NFL season always comes with more questions than answers but thanks to the neverending pandemic, that’s more true than ever! Little to no practice time, preseason or training camp offers gamblers equal opportunity and danger.


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Owing to the dearth of information, Las Vegas knows only slightly more than the average fan, putting everyone more or less on the same playing field. Only the Cleveland Browns, Dallas Cowboys, Indianapolis Colts, Jacksonville Jaguars, Kansas City Chiefs, and Miami Dolphins plan to play with at least some fans in the stands in what is sure to rank as the weirdest season in NFL history. However, whether other teams allow more fans or stop in-person attendance altogether will be decided on many health factors. Without further ado, here are the lines and a little early advice.

Continuity Is King

Due to the lack of practice, teams that have spent the most time together have a leg up on the competition. Look for Patrick Mahomes and the vaunted Kansas City Chiefs offense to put up big numbers early. Defenses will need time to coalesce; the offenses that know themselves inside and out should push the overs. Baltimore is another explosive offense to watch.

Week One NFL Lines

Houston Texans @ (+9.5 -110) SU +325
Kansas City Chiefs (-9.5 -110) SU -450  O/U 54.5

Chicago Bears @ (+3 -115) SU +130
Detroit Lions (-3 -105) SU -150  O/U 43.5

Cleveland Browns @ (+8 -115) SU +280
Baltimore Ravens (-8 -112) SU -360  O/U 48.5

Green Bay Packers @ (+2.5 -105) SU +125
Minnesota Vikings (-2.5 -115) SU -145  O/U 45.5

Indianapolis Colts @ (-7.5 -110) SU -420
Jacksonville Jaguars (+7.5 -110) SU +310  O/U 45

Las Vegas Raiders @ (-3 -120) SU -170
Carolina Panthers (+3 EVEN) SU +150  O/U 47.5

Miami Dolphins @ (+6.5 -106) SU +250
New England Patriots (-6.5 -114) SU -300  O/U 42

New York Jets @ (+6.5 -105) SU +250
Buffalo Bills (-6.5 -115) SU -300  O/U 39.5

Philadelphia Eagles @ (-6 -105) SU -250
Washington (+6 -115) SU +210  O/U 42.5

Los Angeles Chargers @ (-3.0 -120) SU -170
Cincinnati Bengals (+3.0 EVEN) SU +150  O/U 42

Arizona Cardinals @ (+7 -114) SU +260
San Francisco 49ers @ (-7 -106) SU -320  O/U 48

Tampa Bay Buccaneers @ (+3.5 -115) SU +155
New Orleans Saints (-3.5 -105) SU -175  O/U 48

Dallas Cowboys @ (-3 -107) SU -150
Los Angeles Rams (+3 -112) SU +130  O/U 52

Pittsburgh Steelers @ (-6 -108) -245
New York Giants (+6 -112) +205  O/U 46.5

Tennessee Titans @ (-2.5 -113) SU -135
Denver Broncos (+2.5 -108) SU +115  O/U 41

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