The Bills will play the Panthers on Sunday, October 26th, 2025. The matchup takes place at Bank of America Stadium. Watch this exciting Week 8 matchup at 1:03 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.

STATE	Bonus

Matchup Stats
Captain Shady Lines
Best Odds
Interactive Odds Example
Prop Bets
Recent Meetings
Team Standings
Futures Odds
Team Pages
Other Games Today

Key Matchup Stats

The Buffalo Bills and Carolina Panthers will take the field at Bank of America Stadium for a key Week 8 matchup on Sunday, October 26th, 2025. Have a look at each team's key performance stats below as they continue to make their way through the 2025-26 NFL regular season.

SportsBetting3.com Power Rankings - Heading into Week 8 of the 2025-26 season, the Buffalo Bills have a power ranking of 94.67. Our calculations have the Carolina Panthers at a 92.67 power ranking.
Away Buffalo Bills - Now in the middle of the season, the Buffalo Bills have a 1-1-0 record as an away team, ranking them 4th in the league for away team wins.
Home Carolina Panthers - The Carolina Panthers come to this Week 8 matchup with a 3-0-0 record as a home team. They rank 2nd in the league for home team wins so far this season.
Points Scored - The Buffalo Bills currently rank 9th (167) on the edge of Week 8, with the Carolina Panthers ranked 19th (145) for points scored to date.
Points Against - The Buffalo Bills stand 20th (137) in the middle weeks of the regular season for points against. As for the Carolina Panthers, they currently rank 15th (152) for points against.
Team Records - Standings become more important now more than ever. Approaching Week 8, the Buffalo Bills have a 4-2-0 record, with the Carolina Panthers at 4-3-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Arrr, the Buffalo Bills be takin' on the Carolina Panthers in an important Week 8 matchup. Buffalo Bills be standin' at 4-2-0, while Carolina Panthers be standin' at 4-3-0. Mid-season games be crucial for each team's standings.

The battle be happenin' at Bank of America Stadium, a place full of city life and culture. The fans be rowdy, cheerin' on their team with all their might.

According to SportsBetting3.com NFL Power Rankings, Buffalo Bills be at 94.67, while Carolina Panthers be at 92.67. Bet this game at BetMGM or our preferred sports betting partner BetRivers, and look at this game's prop bets. Compare odds from partner sports betting sites to make yer wager wisely. Arrr!

Best Bills at Panthers Odds

**Best Point Spread Betting Odds**
TBD	TBD

Point Spread odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Moneyline Betting Odds**
TBD	TBD

Moneyline odds are updating, please check back soon.

NFL Odds Example

NFL Odds and Outcomes Explained
Game	Book

Buffalo Bills at Carolina Panthers Prop Bets

NFL Prop Bets
+ Displays more odds
	Bet
Bills Panthers 10/26/25 1:03pm EDT	Pending

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 8	Bills vs Panthers Sunday, October 26th, 2025	BUF 40, CAR 9 Bank of America Stadium	Bills by 31
2024 Preseason Week 3	Panthers vs Bills Saturday, August 24th, 2024	CAR 31, BUF 26 Highmark Stadium	Panthers by 5
2022 Preseason Week 3	Bills vs Panthers Friday, August 26th, 2022	CAR 21, BUF 0 Bank of America Stadium	Panthers by 21
2021 Week 15	Panthers vs Bills Sunday, December 19th, 2021	BUF 31, CAR 14 Highmark Stadium	Bills by 17

Team Standings

2025-2026 NFL Regular Season Standings - Buffalo Bills, Carolina Panthers
Team	W	L	T	Pct	PF	PA	Home	Away	Div	Div%	Conf	Conf%	Strk	L5
xy - Buffalo Bills	12	5	0	0.706	481	365	7-2-0	5-3-0	4-2-0	0.667	9-3-0	0.750	1W	4-1-0
xz - Carolina Panthers	8	9	0	0.471	311	380	5-3-0	3-6-0	3-3-0	0.500	6-6-0	0.500	2L	2-3-0

Buffalo Bills & Carolina Panthers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds

No Super Bowl TM Buffalo Bills YR: futures available

Carolina Panthers Futures Odds

No Super Bowl TM Carolina Panthers YR: futures available

Buffalo Bills & Carolina Panthers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Buffalo Bills vs Carolina Panthers NFL Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 26th, 2025 at 1:03 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's NFL page, look for the Buffalo Bills vs Carolina Panthers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Buffalo Bills vs Carolina Panthers Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other October 26, 2025 NFL Games

Odds Preview 1874

Buffalo Bills vs Carolina Panthers Odds

Table of Contents