Buffalo Bills vs Carolina Panthers Odds

The Bills will play the Panthers on Friday, August 26th, 2022. The matchup takes place at Bank of America Stadium. Watch this exciting preseason matchup at 7:00 pm EDT.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props. Read the following to understand point spread betting.

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Point Spread
Underdog

Buffalo Bills
Favorite

Carolina Panthers
+5.5 -105 BetRivers-5.5 -117 BetRivers
SportsBetting3.com has analyzed the latest lines. Review our "Point Spread" table above to smash the books. BetRivers VA has the best favorite Carolina Panthers point spread at -5.5 points. BetRivers has the best underdog Buffalo Bills point spread at +5.5 points. Review our point spread betting tutorial and video for more information.

Total
OverUnder
39.5o -118 BetRivers39.5u -104 BetRivers
The over under line estimates the combined total of each team's final score. BetRivers has the best over line of 39.5 points laying $118 to win $100. BetRivers has the best under line of 39.5 points.

Moneyline
Underdog

Buffalo Bills
Favorite

Carolina Panthers
+185 BetRivers-230 BetRivers
Here are money lines for the outright winner. Favorite Carolina Panthers has a minus value. Lay $230 to win $100 at BetRivers. Underdog Buffalo Bills has a positive value. Risk $100 at BetRivers to win $185.

SportsBetting3.com NFL Odds Example

NFL Odds and Outcomes Explained

Game
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Bills
Panthers
8/26/22 7:00pm EDT

Underdog Buffalo Bills - Buffalo Bills bettors risk $100 to win $95.24 at -105 odds.

A +5.5 Buffalo Bills underdog bet wins if they lose by 5 or fewer, tie, or win outright. Your bet loses if they lose by 6 or more.

Favorite Carolina Panthers - Carolina Panthers bettors risk $100 to win $85.47 at -117 odds.

A -5.5 Carolina Panthers favorite bet wins if they win by 6 or more. Your bet loses if they win by 5 or fewer, tie, or lose outright.

Buffalo Bills at Carolina Panthers Prop Bets

NFL Prop Bets
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Bills
Panthers
8/26/22 7:00pm EDT
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Recent Meetings Since 2018

WeekGameResultMargin
2021
Week 15
Panthers vs Bills
Sunday, December 19th, 2021
BUF 31, CAR 14
Highmark Stadium
Bills by 17
2019
Preseason Week 2
Bills vs Panthers
Friday, August 16th, 2019
BUF 27, CAR 14
Bank of America Stadium
Bills by 13
2018
Preseason Week 1
Panthers vs Bills
Thursday, August 9th, 2018
CAR 28, BUF 23
Highmark Stadium
Panthers by 5

Preseason Team Standings

2022 Preseason Standings
Team Conf Div W L T Pct Home Road Last 5
Buffalo Bills
2-0-0 0-0-0 2 1 0 0.667 2-0-0 0-1-0 2-1-0
Carolina Panthers
1-0-0 0-0-0 2 1 0 0.667 1-0-0 1-1-0 2-1-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 77 46
Total Offensive Yards 1324 642
Total Rushing Yards 337 173
Total Passing Yards 1014 469
Sacks 7 11
Field Goals 4 / 5 1 / 1
Touchdowns 11 5
Turnover Ratio 2

Carolina Panthers Team Stats
Stat Carolina Panthers Opponents
Total 1st Downs 45 60
Total Offensive Yards 829 1046
Total Rushing Yards 345 404
Total Passing Yards 550 642
Sacks 9 5
Field Goals 7 / 7 8 / 10
Touchdowns 5 5
Turnover Ratio 0

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Buffalo Bills Season Win Total
2022 NFL Buffalo Bills Season Win Total
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Buffalo Bills
2022 Season Win Total
Carolina Panthers Season Win Total
2022 NFL Carolina Panthers Season Win Total
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Carolina Panthers
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds
2023 Buffalo Bills Super Bowl Winner Odds

Team
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Carolina Panthers Futures Odds
2023 Carolina Panthers Super Bowl Winner Odds

Team
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Carolina Panthers

2022 Buffalo Bills Games & Results

WeekMatchupDate & Time
Preseason 1Colts vs
Bills
BUF 27, IND 24
Saturday, August 13th, 2022
Preseason 2Broncos vs
Bills
BUF 42, DEN 15
Saturday, August 20th, 2022
Preseason 3Bills vs
Panthers
CAR 21, BUF 0
Friday, August 26th, 2022
Week 1Bills vs
Rams
BUF 31, LAR 10
Thursday, September 8th, 2022
Week 2Titans vs
Bills
BUF 41, TEN 7
Monday, September 19th, 2022
Week 3Bills vs
Dolphins
MIA 21, BUF 19
Sunday, September 25th, 2022
Week 4Bills vs
Ravens
Sunday, October 2nd, 2022
1:00 pm EDT
Week 5Steelers vs
Bills
Sunday, October 9th, 2022
1:00 pm EDT
Week 6Bills vs
Chiefs
Sunday, October 16th, 2022
4:25 pm EDT
Week 7Bills
Bye Week
Week 8Packers vs
Bills
Sunday, October 30th, 2022
8:20 pm EDT
Week 9Bills vs
Jets
Sunday, November 6th, 2022
1:00 pm EST
Week 10Vikings vs
Bills
Sunday, November 13th, 2022
1:00 pm EST
Week 11Browns vs
Bills
Sunday, November 20th, 2022
1:00 pm EST
Week 12Bills vs
Lions
Thursday, November 24th, 2022
12:30 pm EST
Week 13Bills vs
Patriots
Thursday, December 1st, 2022
8:15 pm EST
Week 14Jets vs
Bills
Sunday, December 11th, 2022
1:00 pm EST
Week 15Dolphins vs
Bills
Sunday, December 18th, 2022
12:00 am EST
Week 16Bills vs
Bears
Saturday, December 24th, 2022
1:00 pm EST
Week 17Bills vs
Bengals
Monday, January 2nd, 2023
8:30 pm EST
Week 18Patriots vs
Bills
Sunday, January 8th, 2023
12:00 am EST

2022 Carolina Panthers Games & Results

WeekMatchupDate & Time
Preseason 1Panthers vs
Commanders
CAR 23, WSH 21
Saturday, August 13th, 2022
Preseason 2Panthers vs
Patriots
NE 20, CAR 10
Friday, August 19th, 2022
Preseason 3Bills vs
Panthers
CAR 21, BUF 0
Friday, August 26th, 2022
Week 1Browns vs
Panthers
CLE 26, CAR 24
Sunday, September 11th, 2022
Week 2Panthers vs
Giants
NYG 19, CAR 16
Sunday, September 18th, 2022
Week 3Saints vs
Panthers
CAR 22, NO 14
Sunday, September 25th, 2022
Week 4Cardinals vs
Panthers
Sunday, October 2nd, 2022
4:05 pm EDT
Week 549ers vs
Panthers
Sunday, October 9th, 2022
4:05 pm EDT
Week 6Panthers vs
Rams
Sunday, October 16th, 2022
4:05 pm EDT
Week 7Buccaneers vs
Panthers
Sunday, October 23rd, 2022
1:00 pm EDT
Week 8Panthers vs
Falcons
Sunday, October 30th, 2022
1:00 pm EDT
Week 9Panthers vs
Bengals
Sunday, November 6th, 2022
1:00 pm EST
Week 10Falcons vs
Panthers
Thursday, November 10th, 2022
8:15 pm EST
Week 11Panthers vs
Ravens
Sunday, November 20th, 2022
1:00 pm EST
Week 12Broncos vs
Panthers
Sunday, November 27th, 2022
1:00 pm EST
Week 13Panthers
Bye Week
Week 14Panthers vs
Seahawks
Sunday, December 11th, 2022
4:25 pm EST
Week 15Steelers vs
Panthers
Sunday, December 18th, 2022
1:00 pm EST
Week 16Lions vs
Panthers
Saturday, December 24th, 2022
1:00 pm EST
Week 17Panthers vs
Buccaneers
Sunday, January 1st, 2023
1:00 pm EST
Week 18Panthers vs
Saints
Sunday, January 8th, 2023
12:00 am EST

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