The Cardinals will play the Padres on Sunday, May 10th, 2026. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The St. Louis Cardinals have a 93.00 power ranking. The power ranking for the San Diego Padres is 97.33.
- Visiting St. Louis Cardinals - The St. Louis Cardinals have a 7-4 record as a visiting team, ranking them 3rd Overall for visiting team wins.
- Home San Diego Padres - The San Diego Padres have a 9-4 record as a home team. They rank 1st for home team wins in the Overall standings.
- Runs Scored - The St. Louis Cardinals currently stand 9th (111) Overall, with the San Diego Padres ranking 16th (97) for runs scored.
- Runs Allowed - The St. Louis Cardinals are 5th (119) Overall for runs allowed. The San Diego Padres stand 23rd (79) for runs allowed.
- Team Streaks - The St. Louis Cardinals won their last game. Meanwhile, the San Diego Padres have won their last 3 games.
- Team Records - The St. Louis Cardinals have a 14-9 Overall record (1.5 GB National Central Division), with the San Diego Padres possessing a 16-7 Overall standing (0.0 GB National West Division).
Best Cardinals at Padres Odds
| Underdog St. Louis Cardinals | Favorite San Diego Padres |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The San Diego Padres are the -135 moneyline favorite at BetMGM and the St. Louis Cardinals are the +110 moneyline underdog at BetMGM.
The best over line is 8 -118 runs at BetMGM, which means you risk $118 to win $100 betting the over. The best under line is 8 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.
The San Diego Padres are -1.5 +165 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -200 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cardinals
Padres
5/10/26 4:10pm EDT | +110-135 |
- St. Louis Cardinals bettors risk $100 to win $110 at +110 odds. The implied probability for St. Louis Cardinals is 47.62%.
- San Diego Padres bettors risk $100 to win $74.07 at -135 odds. The implied probability for San Diego Padres is 57.45%.
St. Louis Cardinals at San Diego Padres Prop Bets
| BetMGM Bet |
|
|---|---|
Cardinals
Padres
First Team to Score
5/10/26 4:10pm EDT | -155+118Bet |
Cardinals
Padres
Tie
1st Inning Winner
5/10/26 4:10pm EDT | +290+290-135Bet |
Cardinals
Padres
Tie
First 3 Innings Winner
5/10/26 4:10pm EDT | +145+135+290Bet |
Cardinals
Padres
To Extra Innings
5/10/26 4:10pm EDT | Yes +725No -1200Bet |
| BetMGM | |
Cardinals
Padres
1st Team to Score Will Win
5/10/26 4:10pm EDT | Yes -250No +190Bet |
Padres
Total Runs
STL at SDG 5/10/26 4:10pm EDT | 4.5 o +1154.5 u -150Bet |
Cardinals
Total Runs
STL at SDG 5/10/26 4:10pm EDT | 3.5 o -1403.5 u +105Bet |
St. Louis Cardinals & San Diego Padres Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
St. Louis Cardinals World Series Odds|
Team | BetMGM |
|---|---|
| Cardinals | +10000 Bet |
|
Team | BetMGM |
|---|---|
| Padres | +4000 Bet |
St. Louis Cardinals & San Diego Padres Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 16 | 7 | 0.696 | 0.0 | 9-4 | 7-3 | 97 | 79 | +18 | W3 | 9-1 |
| St. Louis Cardinals | 14 | 9 | 0.609 | +2.0 | 7-5 | 7-4 | 111 | 119 | -8 | W1 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the St. Louis Cardinals vs San Diego Padres MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, May 10th, 2026 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs San Diego Padres Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 10, 2026 MLB Games
- Washington Nationals vs Miami Marlins - 5/10/26 12:15pm EDT
- Oakland Athletics vs Baltimore Orioles - 5/10/26 1:35pm EDT
- Tampa Bay Rays vs Boston Red Sox - 5/10/26 1:35pm EDT
- Colorado Rockies vs Philadelphia Phillies - 5/10/26 1:35pm EDT
- Los Angeles Angels vs Toronto Blue Jays - 5/10/26 1:37pm EDT
- Minnesota Twins vs Cleveland Guardians - 5/10/26 1:40pm EDT
- Houston Astros vs Cincinnati Reds - 5/10/26 1:40pm EDT
- Seattle Mariners vs Chicago White Sox - 5/10/26 2:10pm EDT
- New York Yankees vs Milwaukee Brewers - 5/10/26 2:10pm EDT
- Chicago Cubs vs Texas Rangers - 5/10/26 2:35pm EDT
- Pittsburgh Pirates vs San Francisco Giants - 5/10/26 4:05pm EDT
- New York Mets vs Arizona Diamondbacks - 5/10/26 4:10pm EDT
- Atlanta Braves vs Los Angeles Dodgers - 5/10/26 4:10pm EDT
- Detroit Tigers vs Kansas City Royals - 5/10/26 7:20pm EDT