St. Louis Cardinals vs Houston Astros Odds

The Cardinals will play the Astros on Sunday, April 19th, 2026. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The St. Louis Cardinals have a 95.00 power ranking. The power ranking for the Houston Astros is 88.67.
  • Visiting St. Louis Cardinals - The St. Louis Cardinals have a 5-3 record as a visiting team, ranking them 4th Overall for visiting team wins.
  • Home Houston Astros - The Houston Astros have a 7-5 record as a home team. They rank 3rd for home team wins in the Overall standings.
  • Runs Scored - The St. Louis Cardinals currently stand 10th (96) Overall, with the Houston Astros ranking 2nd (116) for runs scored.
  • Runs Allowed - The St. Louis Cardinals are 4th (106) Overall for runs allowed. The Houston Astros stand 2nd (133) for runs allowed.
  • Team Streaks - The St. Louis Cardinals have won their last 4 games. Meanwhile, the Houston Astros have lost their last 3 games.
  • Team Records - The St. Louis Cardinals have a 12-8 Overall record (0.5 GB National Central Division), with the Houston Astros possessing a 8-14 Overall standing (3.5 GB American West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scurvy dogs! The St. Louis Cardinals be takin' on the Houston Astros...

This Sunday, April 19th, 2026, the Cardinals be lookin' to plunder another victory...

With a solid 12-8 record and a win percentage of 0.600, they be unstoppable...

Meanwhile, them Astros be strugglin' with an 8-14 record and a win percentage of 0.364...

The odds be in favor of the Cardinals, so head on over to SportsBetting3.com...

And bet on this game before it's too late! Review the odds below, ye landlubbers!

Best Cardinals at Astros Odds


Best Moneyline Betting Odds
Underdog

St. Louis Cardinals
Favorite

Houston Astros
The Houston Astros are the -150 moneyline favorite. Risk $150 to win $100 on the Houston Astros at BetMGM. The St. Louis Cardinals are the +125 underdog at BetMGM. Risk $100 to win $125 on the St. Louis Cardinals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $120 to win $100. BetMGM has the best under line of 8.5 runs. Risk $100 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

St. Louis Cardinals
Favorite

Houston Astros
The Houston Astros have a -1.5 +145 run line at BetMGM OH. They are the run line favorite in this matchup. The St. Louis Cardinals have a +1.5 -180 run line at BetMGM OH. The St. Louis Cardinals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the St. Louis Cardinals vs Houston Astros MLB game on Sunday, April 19th, 2026?

The Houston Astros are the -150 moneyline favorite at BetMGM and the St. Louis Cardinals are the +125 moneyline underdog at BetMGM.

What is the over-under total line for the St. Louis Cardinals vs Houston Astros MLB game on Sunday, April 19th, 2026?

The best over line is 8.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 8.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.

What is the run line for the St. Louis Cardinals vs Houston Astros MLB game on Sunday, April 19th, 2026?

The Houston Astros are -1.5 +145 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -180 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cardinals
Astros
4/19/26 2:15pm EDT
+125-150
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • St. Louis Cardinals bettors risk $100 to win $125 at +125 odds. The implied probability for St. Louis Cardinals is 44.44%.
  • Houston Astros bettors risk $100 to win $66.67 at -150 odds. The implied probability for Houston Astros is 60%.

St. Louis Cardinals at Houston Astros Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cardinals
Astros
First Team to Score
4/19/26 2:15pm EDT
-135+105Bet
Cardinals
Astros
Tie
1st Inning Winner
4/19/26 2:15pm EDT
+310+260-125Bet
Cardinals
Astros
Tie
First 3 Innings Winner
4/19/26 2:15pm EDT
+165+115+310Bet
Cardinals
Astros
To Extra Innings
4/19/26 2:15pm EDT
Yes +775No -1400Bet
BetMGM Sports Betting BetMGM
Cardinals
Astros
1st Team to Score Will Win
4/19/26 2:15pm EDT
Yes -250No +190Bet
Astros
Total Runs
STL at HOU
4/19/26 2:15pm EDT
4.5 o -1054.5 u -125Bet
Cardinals
Total Runs
STL at HOU
4/19/26 2:15pm EDT
3.5 o -1453.5 u +110Bet

St. Louis Cardinals & Houston Astros Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
2026 St. Louis Cardinals World Series Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+10000
Bet
Houston Astros World Series Odds
2026 Houston Astros World Series Odds

Team
BetMGM Sports Betting BetMGM
Astros
+8000
Bet

St. Louis Cardinals & Houston Astros Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - St. Louis Cardinals, Houston Astros
Team W L Pct GB Home Away RS RA Diff Strk L10
St. Louis Cardinals1490.609+2.07-57-4111119-8W16-4
Houston Astros9160.360+8.07-62-10135150-15L13-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the St. Louis Cardinals vs Houston Astros MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, April 19th, 2026 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Houston Astros Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Houston Astros Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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