San Francisco Giants vs Washington Nationals Odds

The Giants will play the Nationals on Sunday, May 25th, 2025. Your timezone's first pitch time is 1:35 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the San Francisco Giants possess a 94.67 SportsBetting3.com power ranking. The Washington Nationals now have a 86.67 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting San Francisco Giants - The San Francisco Giants head into this matchup with a 13-13 record as a visiting team. This standing ranks them 4th Overall for visiting team wins.
  • Home Washington Nationals - The Washington Nationals will throw the first pitch possessing a 13-13 home team record. That puts them 7th for home team wins in the Overall MLB standings.
  • Runs Scored - San Francisco Giants batters have produced 234 runs, ranking them 10th Overall, with the Washington Nationals ranking 12th (223) for runs scored.
  • Runs Allowed - San Francisco Giants pitchers and fielders have allowed 191 runs, ranking them 21st Overall for runs allowed. Meanwhile, the Washington Nationals now rank 5th Overall, allowing 270 runs.
  • Team Streaks - The San Francisco Giants lost their last game. Their opponent, the Washington Nationals won their last game.
  • Team Records - Let's review each team's records. The San Francisco Giants have a 30-22 Overall record (2.5 GB National West Division), with the Washington Nationals notching a 24-28 Overall standing (9.5 GB National East Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Giants be takin' on them Nationals on Sunday... (Arrr, they better be ready for a fierce battle at sea!) The Giants be comin' in hot with a 30-22 overall record... (But those scurvy Nationals be showin' some fight with a 7-3 record!)

The Giants be lookin' to plunder another victory on the road... (They be needin' to keep their winnin' ways alive!) The Nationals be lookin' to defend their home turf and make a stand... (But the Giants be comin' to pillage and plunder!)

Bet on MLB baseball at legal US sportsbooks... (Ye can make a pretty penny if ye pick the right side!) Check out this game's prop bets below... (Will the Giants continue their winning streak or will the Nationals reign supreme?)

Review each team's standing at the bottom of the page... (See where they stand in the division and who be chasin' them!) So gather 'round me hearties, it be time for some baseball action... (May the best team be victorious on this fine Sunday afternoon!)

Best Giants at Nationals Odds


Best Moneyline Betting Odds
Underdog

Washington Nationals
Favorite

San Francisco Giants
The San Francisco Giants are the -155 moneyline favorite. Risk $155 to win $100 on the San Francisco Giants at BetMGM. The Washington Nationals are the +130 underdog at BetMGM. Risk $100 to win $130 on the Washington Nationals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8 runs. Risk $102 to win $100. BetMGM has the best under line of 8 runs. Risk $118 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Washington Nationals
Favorite

San Francisco Giants
The San Francisco Giants have a -1.5 +110 run line at BetMGM OH. They are the run line favorite in this matchup. The Washington Nationals have a +1.5 -130 run line at BetMGM OH. The Washington Nationals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Francisco Giants vs Washington Nationals MLB game on Sunday, May 25th, 2025?

The San Francisco Giants are the -155 moneyline favorite at BetMGM and the Washington Nationals are the +130 moneyline underdog at BetMGM.

What is the over-under total line for the San Francisco Giants vs Washington Nationals MLB game on Sunday, May 25th, 2025?

The best over line is 8 -102 runs at BetMGM, which means you risk $102 to win $100 betting the over. The best under line is 8 -118 runs at BetMGM, and that means you risk $118 to win $100 betting the under.

What is the run line for the San Francisco Giants vs Washington Nationals MLB game on Sunday, May 25th, 2025?

The San Francisco Giants are -1.5 +110 run line favorites at BetMGM, while the Washington Nationals are +1.5 -130 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Giants
Nationals
5/25/25 1:35pm EDT
-155+130
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Washington Nationals bettors risk $100 to win $130 at +130 odds. The implied probability for Washington Nationals is 43.48%.
  • San Francisco Giants bettors risk $100 to win $64.52 at -155 odds. The implied probability for San Francisco Giants is 60.78%.

San Francisco Giants at Washington Nationals Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Giants
Nationals
First Team to Score
5/25/25 1:35pm EDT
-185+140Bet
Giants
Nationals
Tie
1st Inning Winner
5/25/25 1:35pm EDT
+280+375-155Bet
Giants
Nationals
Tie
First 3 Innings Winner
5/25/25 1:35pm EDT
+125+180+250Bet
Giants
Nationals
To Extra Innings
5/25/25 1:35pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Giants
Nationals
1st Team to Score Will Win
5/25/25 1:35pm EDT
Yes -250No +190Bet
Giants
Total Runs
SFO at WAS
5/25/25 1:35pm EDT
4.5 o +1004.5 u -130Bet
Nationals
Total Runs
SFO at WAS
5/25/25 1:35pm EDT
3.5 o +1003.5 u -130Bet
Michael Soroka
Strikeouts Thrown
SFO at WAS
5/25/25 1:35pm EDT
5.5 o +1155.5 u -150Bet
BetMGM Sports Betting BetMGM
Robbie Ray
Strikeouts Thrown
SFO at WAS
5/25/25 1:35pm EDT
6.5 o -1106.5 u -118Bet

San Francisco Giants & Washington Nationals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds
2025 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+3500
Bet
Washington Nationals World Series Odds
2025 Washington Nationals World Series Odds

Team
BetMGM Sports Betting BetMGM
Nationals
+50000
Bet

San Francisco Giants & Washington Nationals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Francisco Giants, Washington Nationals
Team W L Pct GB Home Away RS RA Diff Strk L10
San Francisco Giants31240.564+4.517-914-15239199+40L25-5
Washington Nationals24290.453+10.513-1411-15225273-48L17-3

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco Giants vs Washington Nationals MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, May 25th, 2025 at 1:35 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Washington Nationals Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Washington Nationals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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