Boston Red Sox vs San Francisco Giants Odds

The Red Sox will play the Giants on Sunday, June 22nd, 2025. Your timezone's first pitch time is 4:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the Boston Red Sox possess a 91.00 SportsBetting3.com power ranking. The San Francisco Giants now have a 95.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Boston Red Sox - The Boston Red Sox head into this matchup with a 11-15 record as a visiting team. This standing ranks them 7th Overall for visiting team wins.
  • Home San Francisco Giants - The San Francisco Giants will throw the first pitch possessing a 17-9 home team record. That puts them 4th for home team wins in the Overall MLB standings.
  • Runs Scored - Boston Red Sox batters have produced 269 runs, ranking them 6th Overall, with the San Francisco Giants ranking 10th (239) for runs scored.
  • Runs Allowed - Boston Red Sox pitchers and fielders have allowed 252 runs, ranking them 8th Overall for runs allowed. Meanwhile, the San Francisco Giants now rank 22nd Overall, allowing 199 runs.
  • Team Streaks - The Boston Red Sox have lost their last 3 games. Their opponent, the San Francisco Giants have lost their last 2 games.
  • Team Records - Let's review each team's records. The Boston Red Sox have a 27-29 Overall record (8.5 GB American East Division), with the San Francisco Giants notching a 31-24 Overall standing (3.0 GB National West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Boston Red Sox be sailin' to face the scurvy San Francisco Giants on Sunday... Red Sox be walkin' the plank with a sorry 27-29 record... (Aye, they be needin' a boost to their win percentage to 0.482) But fear not, they be holdin' steady with a 5-5 record in their last 10 games...

The Giants be standin' tall with a 31-24 record... (0.564 win percentage, aye) Their last 10 games be a match for the Red Sox at 5-5... (But will they be able to outsmart the Red Sox on their home turf?)

Shiver me timbers, this be a game ye won't want to miss... (Be sure to check out this game's prop bets below. Bet on MLB baseball at legal US sportsbooks!) Review each team's standing at the bottom of the page... (And may the best team hoist the Jolly Roger high!)

Best Red Sox at Giants Odds


Best Moneyline Betting Odds
Underdog

Boston Red Sox
Favorite

San Francisco Giants
The San Francisco Giants are the -160 moneyline favorite. Risk $160 to win $100 on the San Francisco Giants at BetMGM. The Boston Red Sox are the +135 underdog at BetMGM. Risk $100 to win $135 on the Boston Red Sox. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $105 to win $100. BetMGM has the best under line of 7.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Boston Red Sox
Favorite

San Francisco Giants
The San Francisco Giants have a -1.5 +140 run line at BetMGM OH. They are the run line favorite in this matchup. The Boston Red Sox have a +1.5 -170 run line at BetMGM OH. The Boston Red Sox are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Boston Red Sox vs San Francisco Giants MLB game on Sunday, June 22nd, 2025?

The San Francisco Giants are the -160 moneyline favorite at BetMGM and the Boston Red Sox are the +135 moneyline underdog at BetMGM.

What is the over-under total line for the Boston Red Sox vs San Francisco Giants MLB game on Sunday, June 22nd, 2025?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Boston Red Sox vs San Francisco Giants MLB game on Sunday, June 22nd, 2025?

The San Francisco Giants are -1.5 +140 run line favorites at BetMGM, while the Boston Red Sox are +1.5 -170 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Red Sox
Giants
4:05pm EDT
+135-160
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Boston Red Sox bettors risk $100 to win $135 at +135 odds. The implied probability for Boston Red Sox is 42.55%.
  • San Francisco Giants bettors risk $100 to win $62.5 at -160 odds. The implied probability for San Francisco Giants is 61.54%.

Boston Red Sox at San Francisco Giants Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Red Sox
Giants
First Team to Score
4:05pm EDT
-115-110Bet
Red Sox
Giants
Tie
1st Inning Winner
4:05pm EDT
+375+270-150Bet
Red Sox
Giants
Tie
First 3 Innings Winner
4:05pm EDT
+200+110+250Bet
Red Sox
Giants
To Extra Innings
4:05pm EDT
Yes +700No -1100Bet
BetMGM Sports Betting BetMGM

Boston Red Sox & San Francisco Giants Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Boston Red Sox World Series Odds
2025 Boston Red Sox World Series Odds

Team
BetMGM Sports Betting BetMGM
Red Sox
+5000
Bet
San Francisco Giants World Series Odds
2025 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+2500
Bet

Boston Red Sox & San Francisco Giants Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Boston Red Sox, San Francisco Giants
Team W L Pct GB Home Away RS RA Diff Strk L10
San Francisco Giants31240.564+4.517-914-15239199+40L25-5
Boston Red Sox27290.482+9.016-1411-15269252+17L35-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Boston Red Sox vs San Francisco Giants MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 22nd, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Boston Red Sox vs San Francisco Giants Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Boston Red Sox vs San Francisco Giants Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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