SMU vs Clemson Football Odds

The Mustangs will play the Tigers on Saturday, October 18th, 2025. The matchup takes place at Memorial Stadium (Clemson, SC). Watch this exciting Week 8 matchup at 3:30 pm EDT. Check local listings for coverage on ACC Network.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 8 action features a matchup between SMU and Clemson taking place at Memorial Stadium (Clemson, SC). The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - SMU has a 95.33 conference power ranking for the 2025 season. The conference power ranking for Clemson is 94.00.
  • Away SMU - Heading into Week 8, SMU currently has a 1-1 record as an away team for the 2025 regular season. This ranks them 2nd in the ACC Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Clemson - Clemson has a 1-2 record as a home team. Looking ahead to this 2025 Week 8 matchup, they rank 4th in the ACC Conference for home team wins. Like the SMU away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, SMU ranks 7th (204) in the ACC Conference, with Clemson currently ranking 13th (158) for points scored in the ACC Conference.
  • Points Against - Also in 2025, SMU stands 10th (134) in the ACC Conference for points scored by opponents in 2025. Clemson sits at 13th (111) in the ACC Conference for points against in the 2025 season so far.
  • Team Records - SMU has a 4-2 overall record for the 2025 regular season, with Clemson currently 3-3 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Top o' the morning to ya, college football fans! SMU is on the road to face Clemson.

This key Week 8 matchup will be held at Memorial Stadium in sunny Clemson, SC.

According to SportsBetting3.com Power Rankings, SMU has the edge with 95.33 over Clemson's 94.00.

SMU comes in with a 4-2 record, while Clemson currently sits at 3-3. Bet this game at BetRivers, or BetMGM. Review this game's prop bets and compare the odds below.

Best Mustangs at Tigers Odds


Best Point Spread Betting Odds
Underdog

SMU
Favorite

Clemson
Clemson has a -9.5 +100 point spread at BetMGM OH. They are the point spread favorite in this matchup. SMU has a +9.5 -120 point spread at BetMGM OH. SMU is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 55.5 points. Risk $105 to win $100. BetMGM has the best under line of 55.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

SMU
Favorite

Clemson
Clemson is the -350 moneyline favorite. Risk $350 to win $100 on Clemson at BetMGM. SMU is the +270 underdog at BetMGM. Risk $100 to win $270 on SMU. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the SMU vs Clemson College Football game on Saturday, October 18th, 2025?

Clemson is a -9.5 +100 point spread favorite at BetMGM, while SMU is a +9.5 -120 point spread underdog at BetMGM.

What is the over-under total line for the SMU vs Clemson College Football game on Saturday, October 18th, 2025?

The best over line is 55.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 55.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the SMU vs Clemson College Football game on Saturday, October 18th, 2025?

Clemson is a -350 moneyline favorite at BetMGM and SMU is a +270 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
SMU
Clemson
10/18/25 3:30pm EDT
+9.5 -120-9.5 +100
Bet $100 at BetMGM Ohio
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Underdog SMU - SMU bettors risk $100 to win $83.33 at -120 odds.

A +9.5 SMU underdog bet wins if they lose by 9 or fewer, tie, or win outright. Your bet loses if they lose by 10 or more.

Favorite Clemson - Clemson bettors risk $100 to win $100 at +100 odds.

A -9.5 Clemson favorite bet wins if they win by 10 or more. Your bet loses if they win by 9 or fewer, tie, or lose outright.

SMU at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
SMU
Clemson
10/18/25 3:30pm EDT
Pending BetMGM

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 15
Clemson vs SMU
Saturday, December 7th, 2024
CLEM 34, SMU 31
Bank of America Stadium
Clemson by 3

Team Standings

2025-2026 College Football Regular Season Standings - SMU, Clemson
Team Conf Conf% W L PF PA Home Away Strk
SMU2-01.000422041343-11-1W2
Clemson2-20.500331581111-22-1W2

SMU & Clemson Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

SMU Championship Odds
2025-26 SMU NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
SMU
+30000
Bet
Clemson Championship Odds
2025-26 Clemson NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Clemson
+15000
Bet

SMU & Clemson Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 SMU Games & Results
WeekMatchupDate & Result
Week 1East Texas A&M vs
SMU
SMU 42, ETAM 13
Saturday, August 30th, 2025
Week 2Baylor vs
SMU
BAY 48, SMU 45 (2OT)
Saturday, September 6th, 2025
Week 3SMU vs
Missouri State
SMU 28, MOST 10
Saturday, September 13th, 2025
Week 4SMU vs
TCU
TCU 35, SMU 24
Saturday, September 20th, 2025
Week 6Syracuse vs
SMU
SMU 31, SYR 18
Saturday, October 4th, 2025
Week 7Stanford vs
SMU
SMU 34, STAN 10
Saturday, October 11th, 2025
Week 8SMU vs
Clemson
Saturday, October 18th, 2025
3:30 pm EDT
Week 9SMU vs
Wake Forest
Saturday, October 25th, 2025
12:00 pm EDT
Week 10Miami (FL) vs
SMU
Saturday, November 1st, 2025
12:00 am EDT
Week 11SMU vs
Boston College
Saturday, November 8th, 2025
12:00 am EST
Week 13Louisville vs
SMU
Saturday, November 22nd, 2025
12:00 am EST
Week 14SMU vs
California
Saturday, November 29th, 2025
12:00 am EST


2025-26 Clemson Games & Results
WeekMatchupDate & Result
Week 1LSU vs
Clemson
LSU 17, CLEM 10
Saturday, August 30th, 2025
Week 2Troy vs
Clemson
CLEM 27, TROY 16
Saturday, September 6th, 2025
Week 3Clemson vs
Georgia Tech
GT 24, CLEM 21
Saturday, September 13th, 2025
Week 4Syracuse vs
Clemson
SYR 34, CLEM 21
Saturday, September 20th, 2025
Week 6Clemson vs
North Carolina
CLEM 38, UNC 10
Saturday, October 4th, 2025
Week 7Clemson vs
Boston College
CLEM 41, BC 10
Saturday, October 11th, 2025
Week 8SMU vs
Clemson
Saturday, October 18th, 2025
3:30 pm EDT
Week 10Duke vs
Clemson
Saturday, November 1st, 2025
12:00 am EDT
Week 11Florida State vs
Clemson
Saturday, November 8th, 2025
12:00 am EST
Week 12Clemson vs
Louisville
Friday, November 14th, 2025
7:30 pm EST
Week 13Furman vs
Clemson
Saturday, November 22nd, 2025
12:00 am EST
Week 14Clemson vs
South Carolina
Saturday, November 29th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the SMU vs Clemson College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 18th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the SMU vs Clemson Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the SMU vs Clemson Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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