Iowa State vs Oklahoma State Football Odds

The Cyclones will play the Cowboys on Saturday, November 29th, 2025. The matchup takes place at Boone Pickens Stadium. Watch this exciting Week 14 matchup at 12:00 pm EST. Check local listings for coverage on ESPNU.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Matchup Stats
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Best Odds
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Key Matchup Stats

We're now in the home stretch of the 2025 college football season, with Iowa State and Oklahoma State meeting at Boone Pickens Stadium for a key late-season matchup on Saturday, November 29th, 2025. The playoffs are fast approaching, along with the annual Bowl games that kick off in December. Here's an overview of some important 2025 performance data for each team.

SportsBetting3.com Power Rankings - As we wrap up the 2025 regular season, Iowa State has notched a 96.67 Big 12 Conference conference power ranking. On the other side of the gridiron, Oklahoma State has a 90.00 Big 12 Conference power ranking.
Away Iowa State - Looking at Week 14, Iowa State heads into this matchup with a 2-2 record as an away team. This ranks them 4th in the Big 12 Conference for away team wins in 2025. Remember that a team's overall record and schedule strength will affect whether or not they make a December bowl game or qualify for the playoffs.
Home Oklahoma State - Meanwhile, Oklahoma State has a 1-5 record as a home team for 2025. They currently rank 6th in the Big 12 Conference for home team wins. Let's see if they can add another win to their record when they battle Iowa State on Saturday, November 29th, 2025.
Points Scored - Now late in the 2025 season, Iowa State ranks 10th (309) in the Big 12 Conference, with Oklahoma State currently ranking 15th (157) for points scored in the Big 12 Conference.
Points Against - Iowa State currently stands 11th (229) in the Big 12 Conference for points scored by opponents in the 2025 college football season. Their opponent, Oklahoma State, ranks 1st (380) in the Big 12 Conference for points against them as the 2025 college football season comes to a close.
Team Records - As we head into Week 14, Iowa State has a 7-4 overall record for the 2025 regular season, with Oklahoma State possessing a 1-10 standing for the 2025 college football season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Get ready for a wild showdown as Iowa State faces Oklahoma State on Saturday!

Boone Pickens Stadium will be rocking for this crucial Week 14 matchup.

The regular season is winding down, with bowl games just around the corner.

Iowa State holds a higher Power Ranking than Oklahoma State in this matchup.

With a 7-4 record, Iowa State looks to continue their winning ways.

On the other hand, Oklahoma State has struggled this season with a 1-10 record.

For a bet on this game, we recommend BetRivers or BetMGM.

Review this game's prop bets and compare the best point spread, total, and moneylines.

Best Cyclones at Cowboys Odds

**Best Point Spread Betting Odds**
Underdog Oklahoma State	Favorite Iowa State
+13.5 -110 BetMGM Bet	-13.5 -110 BetMGM Bet

Iowa State has a -13.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. Oklahoma State has a +13.5 -110 point spread at BetMGM OH. Oklahoma State is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
45.5 o -115 BetMGM Bet	45.5 u -105 BetMGM Bet

BetMGM has the best over line of 45.5 points. Risk $115 to win $100. BetMGM has the best under line of 45.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Oklahoma State	Favorite Iowa State
+425 BetMGM Bet	-600 BetMGM Bet

Iowa State is the -600 moneyline favorite. Risk $600 to win $100 on Iowa State at BetMGM. Oklahoma State is the +425 underdog at BetMGM. Risk $100 to win $425 on Oklahoma State. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Iowa State vs Oklahoma State College Football game on Saturday, November 29th, 2025?

Iowa State is a -13.5 -110 point spread favorite at BetMGM, while Oklahoma State is a +13.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the Iowa State vs Oklahoma State College Football game on Saturday, November 29th, 2025?

The best over line is 45.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 45.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the moneyline for the Iowa State vs Oklahoma State College Football game on Saturday, November 29th, 2025?

Iowa State is a -600 moneyline favorite at BetMGM and Oklahoma State is a +425 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Iowa State Oklahoma State 11/29/25 12:00pm EST	-13.5 -110 +13.5 -110

Bet $100 at BetMGM Ohio
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Underdog Oklahoma State - Oklahoma State bettors risk $100 to win $90.91 at -110 odds.

A +13.5 Oklahoma State underdog bet wins if they lose by 13 or fewer, tie, or win outright. Your bet loses if they lose by 14 or more.

Favorite Iowa State - Iowa State bettors risk $100 to win $90.91 at -110 odds.

A -13.5 Iowa State favorite bet wins if they win by 14 or more. Your bet loses if they win by 13 or fewer, tie, or lose outright.

Iowa State at Oklahoma State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Iowa State Oklahoma State No Touchdown To Score 1st Touchdown 11/29/25 12:00pm EST	-275 +180 +10000 Bet
Iowa State Oklahoma State Game to Overtime 11/29/25 12:00pm EST	Yes +1400 No -10000 Bet
Iowa State Oklahoma State Both Teams Score 10+ 11/29/25 12:00pm EST	Yes -375 No +275 Bet
Iowa State Oklahoma State Both Teams Score 20+ 11/29/25 12:00pm EST	Yes +180 No -235 Bet
	BetMGM
Iowa State Oklahoma State Both Teams Score 30+ 11/29/25 12:00pm EST	Yes +1100 No -5000 Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 14	Iowa State vs Oklahoma State Saturday, November 29th, 2025	ISU 20, OKST 13 Boone Pickens Stadium	Iowa State by 7
2023 Week 4	Oklahoma State vs Iowa State Saturday, September 23rd, 2023	ISU 34, OKST 27 Jack Trice Stadium	Iowa State by 7
2022 Week 11	Iowa State vs Oklahoma State Saturday, November 12th, 2022	OKST 20, ISU 14 Boone Pickens Stadium	Oklahoma State by 6
2021 Week 8	Oklahoma State vs Iowa State Saturday, October 23rd, 2021	ISU 24, OKST 21 Jack Trice Stadium	Iowa State by 3

Team Standings

2025-2026 College Football Regular Season Standings - Iowa State, Oklahoma State
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Iowa State	5-4	0.556	8	4	329	242	4-2	3-2	W3
Oklahoma State	0-9	0.000	1	11	170	400	1-6	0-5	L11

Iowa State & Oklahoma State Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Iowa State Championship Odds

No NCAA College Football Championship TM Iowa State YR: futures available

Oklahoma State Championship Odds

No NCAA College Football Championship TM Oklahoma State YR: futures available

Iowa State & Oklahoma State Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Iowa State Games & Results
Week	Matchup	Date & Result
Week 1	Iowa State vs Kansas State	ISU 24, KSU 21 Saturday, August 23rd, 2025
Week 1	South Dakota vs Iowa State	ISU 55, SDAK 7 Saturday, August 30th, 2025
Week 2	Iowa vs Iowa State	ISU 16, IOWA 13 Saturday, September 6th, 2025
Week 3	Iowa State vs Arkansas State	ISU 24, ARST 16 Saturday, September 13th, 2025
Week 5	Arizona vs Iowa State	ISU 39, ARIZ 14 Saturday, September 27th, 2025
Week 6	Iowa State vs Cincinnati	CIN 38, ISU 30 Saturday, October 4th, 2025
Week 7	Iowa State vs Colorado	COLO 24, ISU 17 Saturday, October 11th, 2025
Week 9	BYU vs Iowa State	BYU 41, ISU 27 Saturday, October 25th, 2025
Week 10	Arizona State vs Iowa State	ASU 24, ISU 19 Saturday, November 1st, 2025
Week 11	Iowa State vs TCU	ISU 20, TCU 17 Saturday, November 8th, 2025
Week 13	Kansas vs Iowa State	ISU 38, KU 14 Saturday, November 22nd, 2025
Week 14	Iowa State vs Oklahoma State	ISU 20, OKST 13 Saturday, November 29th, 2025

2025-26 Oklahoma State Games & Results
Week	Matchup	Date & Result
Week 1	UT-Martin vs Oklahoma State	OKST 27, UTM 7 Thursday, August 28th, 2025
Week 2	Oklahoma State vs Oregon	ORE 69, OKST 3 Saturday, September 6th, 2025
Week 4	Tulsa vs Oklahoma State	TLSA 19, OKST 12 Friday, September 19th, 2025
Week 5	Baylor vs Oklahoma State	BAY 45, OKST 27 Saturday, September 27th, 2025
Week 6	Oklahoma State vs Arizona	ARIZ 41, OKST 13 Saturday, October 4th, 2025
Week 7	Houston vs Oklahoma State	HOU 39, OKST 17 Saturday, October 11th, 2025
Week 8	Cincinnati vs Oklahoma State	CIN 49, OKST 17 Saturday, October 18th, 2025
Week 9	Oklahoma State vs Texas Tech	TTU 42, OKST 0 Saturday, October 25th, 2025
Week 10	Oklahoma State vs Kansas	KU 38, OKST 21 Saturday, November 1st, 2025
Week 12	Kansas State vs Oklahoma State	KSU 14, OKST 6 Saturday, November 15th, 2025
Week 13	Oklahoma State vs UCF	UCF 17, OKST 14 Saturday, November 22nd, 2025
Week 14	Iowa State vs Oklahoma State	ISU 20, OKST 13 Saturday, November 29th, 2025

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Iowa State vs Oklahoma State College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 29th, 2025 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Iowa State vs Oklahoma State Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Iowa State vs Oklahoma State Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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