Baltimore Orioles vs San Diego Padres Odds

The Orioles will play the Padres on Wednesday, September 3rd, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Orioles at Padres Odds


Best Moneyline Betting Odds
Underdog

Baltimore Orioles
Favorite

San Diego Padres
The San Diego Padres are the -165 moneyline favorite. Risk $165 to win $100 on the San Diego Padres at BetMGM. The Baltimore Orioles are the +140 underdog at BetMGM. Risk $100 to win $140 on the Baltimore Orioles. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $105 to win $100. BetMGM has the best under line of 8.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Baltimore Orioles
Favorite

San Diego Padres
The San Diego Padres have a -1.5 +130 run line at BetMGM OH. They are the run line favorite in this matchup. The Baltimore Orioles have a +1.5 -155 run line at BetMGM OH. The Baltimore Orioles are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Baltimore Orioles vs San Diego Padres MLB game on Wednesday, September 3rd, 2025?

The San Diego Padres are the -165 moneyline favorite at BetMGM and the Baltimore Orioles are the +140 moneyline underdog at BetMGM.

What is the over-under total line for the Baltimore Orioles vs San Diego Padres MLB game on Wednesday, September 3rd, 2025?

The best over line is 8.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 8.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Baltimore Orioles vs San Diego Padres MLB game on Wednesday, September 3rd, 2025?

The San Diego Padres are -1.5 +130 run line favorites at BetMGM, while the Baltimore Orioles are +1.5 -155 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Orioles
Padres
9/03/25 4:10pm EDT
+140-165
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Baltimore Orioles bettors risk $100 to win $140 at +140 odds. The implied probability for Baltimore Orioles is 41.67%.
  • San Diego Padres bettors risk $100 to win $60.61 at -165 odds. The implied probability for San Diego Padres is 62.26%.

Baltimore Orioles at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Orioles
Padres
First Team to Score
9/03/25 4:10pm EDT
-130+100Bet
Orioles
Padres
Tie
1st Inning Winner
9/03/25 4:10pm EDT
+320+250-125Bet
Orioles
Padres
Tie
First 3 Innings Winner
9/03/25 4:10pm EDT
+170+110+300Bet
Orioles
Padres
To Extra Innings
9/03/25 4:10pm EDT
Yes +800No -1400Bet
BetMGM Sports Betting BetMGM
Orioles
Padres
1st Team to Score Will Win
9/03/25 4:10pm EDT
Yes -250No +190Bet
Orioles
Total Runs
BAL at SDG
9/03/25 4:10pm EDT
3.5 o -1153.5 u -110Bet
Padres
Total Runs
BAL at SDG
9/03/25 4:10pm EDT
4.5 o -1054.5 u -125Bet
Cade Povich
Strikeouts Thrown
BAL at SDG
9/03/25 4:10pm EDT
4.5 o +1104.5 u -145Bet
BetMGM Sports Betting BetMGM
Nestor Cortes
Strikeouts Thrown
BAL at SDG
9/03/25 4:10pm EDT
5.5 o -1105.5 u -118Bet

Baltimore Orioles & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Baltimore Orioles World Series Odds
2025 Baltimore Orioles World Series Odds

Team
BetMGM Sports Betting BetMGM
Orioles
San Diego Padres World Series Odds
2025 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+1400
Bet

Baltimore Orioles & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Baltimore Orioles, San Diego Padres
Team W L Pct GB Home Away RS RA Diff Strk L10
San Diego Padres80670.544+9.045-2735-40619565+54W14-6
Baltimore Orioles69770.473+19.536-3833-39628707-79W38-2

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Baltimore Orioles vs San Diego Padres MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 3rd, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Baltimore Orioles vs San Diego Padres Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Baltimore Orioles vs San Diego Padres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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