The Red Sox will play the Giants on Sunday, June 22nd, 2025. Your timezone's first pitch time is 4:05 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the Boston Red Sox possess a 91.00 SportsBetting3.com power ranking. The San Francisco Giants now have a 95.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting Boston Red Sox - The Boston Red Sox head into this matchup with a 11-15 record as a visiting team. This standing ranks them 7th Overall for visiting team wins.
- Home San Francisco Giants - The San Francisco Giants will throw the first pitch possessing a 17-9 home team record. That puts them 4th for home team wins in the Overall MLB standings.
- Runs Scored - Boston Red Sox batters have produced 269 runs, ranking them 6th Overall, with the San Francisco Giants ranking 10th (239) for runs scored.
- Runs Allowed - Boston Red Sox pitchers and fielders have allowed 252 runs, ranking them 8th Overall for runs allowed. Meanwhile, the San Francisco Giants now rank 22nd Overall, allowing 199 runs.
- Team Streaks - The Boston Red Sox have lost their last 3 games. Their opponent, the San Francisco Giants have lost their last 2 games.
- Team Records - Let's review each team's records. The Boston Red Sox have a 27-29 Overall record (8.5 GB American East Division), with the San Francisco Giants notching a 31-24 Overall standing (3.0 GB National West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Boston Red Sox be sailin' to face the scurvy San Francisco Giants on Sunday... Red Sox be walkin' the plank with a sorry 27-29 record... (Aye, they be needin' a boost to their win percentage to 0.482) But fear not, they be holdin' steady with a 5-5 record in their last 10 games...
The Giants be standin' tall with a 31-24 record... (0.564 win percentage, aye) Their last 10 games be a match for the Red Sox at 5-5... (But will they be able to outsmart the Red Sox on their home turf?)
Shiver me timbers, this be a game ye won't want to miss... (Be sure to check out this game's prop bets below. Bet on MLB baseball at legal US sportsbooks!) Review each team's standing at the bottom of the page... (And may the best team hoist the Jolly Roger high!)
Best Red Sox at Giants Odds
| Underdog Boston Red Sox | Favorite San Francisco Giants |
|---|---|
| Over | Under |
|---|---|
| Underdog Boston Red Sox | Favorite San Francisco Giants |
|---|---|
Matchup Odds FAQs
The San Francisco Giants are the -167 moneyline favorite at BetRivers and the Boston Red Sox are the +135 moneyline underdog at BetRivers.
The best over line is 7.5 -105 runs at BetRivers, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -118 runs at BetRivers, and that means you risk $118 to win $100 betting the under.
The San Francisco Giants are -1.5 +132 run line favorites at BetRivers, while the Boston Red Sox are +1.5 -165 run line underdogs at BetRivers.
MLB Odds Example
|
Game |
 BetRiversBet |
|---|---|
Red Sox
Giants
6/22/25 4:05pm EDT | +135-167 |
- Boston Red Sox bettors risk $100 to win $135 at +135 odds. The implied probability for Boston Red Sox is 42.55%.
- San Francisco Giants bettors risk $100 to win $59.88 at -167 odds. The implied probability for San Francisco Giants is 62.55%.
Boston Red Sox at San Francisco Giants Prop Bets
| BetRivers Bet |
|
|---|---|
Red Sox
Giants
Tie
1st Inning Winner
6/22/25 4:05pm EDT | +375+255-152Bet |
Red Sox
Total Runs
BOS at SFO 6/22/25 4:05pm EDT | 3.5 o +1103.5 u -139Bet |
Giants
Total Runs
BOS at SFO 6/22/25 4:05pm EDT | 3.5 o -1503.5 u +117Bet |
Boston Red Sox & San Francisco Giants Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Boston Red Sox World Series Odds|
Team | BetRivers |
|---|---|
| Red Sox | +1400 Bet |
No World Series TM San Francisco Giants YR: futures available
Boston Red Sox & San Francisco Giants Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| y - Boston Red Sox | 89 | 73 | 0.549 | +8.0 | 48-33 | 41-40 | 786 | 676 | +110 | W1 | 6-4 |
| e - San Francisco Giants | 81 | 81 | 0.500 | +16.0 | 42-39 | 39-42 | 705 | 684 | +21 | W4 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Boston Red Sox vs San Francisco Giants MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 22nd, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Boston Red Sox vs San Francisco Giants Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Boston Red Sox vs San Francisco Giants Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other June 22, 2025 MLB Games
- Baltimore Orioles vs New York Yankees
- Detroit Tigers vs Tampa Bay Rays
- Texas Rangers vs Pittsburgh Pirates
- Chicago White Sox vs Toronto Blue Jays
- Atlanta Braves vs Miami Marlins
- Milwaukee Brewers vs Minnesota Twins
- Cincinnati Reds vs St. Louis Cardinals
- Seattle Mariners vs Chicago Cubs
- Arizona Diamondbacks vs Colorado Rockies
- Cleveland Guardians vs Oakland Athletics
- Houston Astros vs Los Angeles Angels
- Washington Nationals vs Los Angeles Dodgers
- Kansas City Royals vs San Diego Padres
- New York Mets vs Philadelphia Phillies