The Cubs will play the Giants on Sunday, February 22nd, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Cubs at Giants Odds
| Underdog Chicago Cubs | Favorite San Francisco Giants |
|---|---|
| Over | Under |
|---|---|
| Underdog Chicago Cubs | Favorite San Francisco Giants |
|---|---|
Matchup Odds FAQs
The San Francisco Giants are the -143 moneyline favorite at BetRivers and the Chicago Cubs are the +120 moneyline underdog at BetMGM.
The best over line is 10.5 -110 runs at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 10.5 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco Giants are -1.5 +140 run line favorites at BetMGM, while the Chicago Cubs are +1.5 -170 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cubs
Giants
2/22/26 3:05pm EST | +120-145 |
- Chicago Cubs bettors risk $100 to win $120 at +120 odds. The implied probability for Chicago Cubs is 45.45%.
- San Francisco Giants bettors risk $100 to win $68.97 at -145 odds. The implied probability for San Francisco Giants is 59.18%.
Chicago Cubs at San Francisco Giants Prop Bets
| BetMGM Bet |
|
|---|---|
Cubs
Giants
2/22/26 3:05pm EST | Pending BetMGM |
Chicago Cubs & San Francisco Giants Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Chicago Cubs World Series Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| Cubs | +2000 Bet | +1800 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Giants | +6600 Bet | +4000 Bet |
Chicago Cubs & San Francisco Giants Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| y - Chicago Cubs | 92 | 70 | 0.568 | +5.0 | 50-31 | 42-39 | 793 | 649 | +144 | W3 | 4-6 |
| e - San Francisco Giants | 81 | 81 | 0.500 | +16.0 | 42-39 | 39-42 | 705 | 684 | +21 | W4 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Chicago Cubs vs San Francisco Giants MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, February 22nd, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Chicago Cubs vs San Francisco Giants Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago Cubs vs San Francisco Giants Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other February 22, 2026 MLB Games
- Baltimore Orioles vs Detroit Tigers - 2/22/26 1:05pm EST
- Minnesota Twins vs Atlanta Braves - 2/22/26 1:05pm EST
- New York Mets vs New York Yankees - 2/22/26 1:05pm EST
- St. Louis Cardinals vs Houston Astros - 2/22/26 1:05pm EST
- Toronto Blue Jays vs Boston Red Sox - 2/22/26 1:05pm EST
- Washington Nationals vs Miami Marlins - 2/22/26 1:10pm EST
- Seattle Mariners vs Cincinnati Reds - 2/22/26 3:05pm EST
- Colorado Rockies vs Texas Rangers - 2/22/26 3:05pm EST
- Cleveland Guardians vs Oakland Athletics - 2/22/26 3:05pm EST
- Los Angeles Angels vs Arizona Diamondbacks - 2/22/26 3:10pm EST
- Los Angeles Dodgers vs San Diego Padres - 2/22/26 3:10pm EST