Chicago Cubs vs San Francisco Giants Odds

The Cubs will play the Giants on Thursday, August 28th, 2025. Your timezone's first pitch time is 3:45 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Cubs at Giants Odds


Best Moneyline Betting Odds
Underdog

San Francisco Giants
Favorite

Chicago Cubs
The Chicago Cubs are the -110 moneyline favorite. Risk $110 to win $100 on the Chicago Cubs at BetMGM. The San Francisco Giants are the -110 underdog at BetMGM. Risk $110 to win $100 on the San Francisco Giants. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7 runs. Risk $125 to win $100. BetMGM has the best under line of 7 runs. Risk $100 to win $105. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Francisco Giants
Favorite

Chicago Cubs
The Chicago Cubs have a -1.5 +165 run line at BetMGM OH. They are the run line favorite in this matchup. The San Francisco Giants have a +1.5 -200 run line at BetMGM OH. The San Francisco Giants are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Chicago Cubs vs San Francisco Giants MLB game on Thursday, August 28th, 2025?

The Chicago Cubs are the -110 moneyline favorite at BetMGM and the San Francisco Giants are the -110 moneyline underdog at BetMGM.

What is the over-under total line for the Chicago Cubs vs San Francisco Giants MLB game on Thursday, August 28th, 2025?

The best over line is 7 -125 runs at BetMGM, which means you risk $125 to win $100 betting the over. The best under line is 7 +105 runs at BetMGM, and that means you risk $100 to win $105 betting the under.

What is the run line for the Chicago Cubs vs San Francisco Giants MLB game on Thursday, August 28th, 2025?

The Chicago Cubs are -1.5 +165 run line favorites at BetMGM, while the San Francisco Giants are +1.5 -200 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cubs
Giants
8/28/25 3:45pm EDT
-110-110
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • San Francisco Giants bettors risk $100 to win $90.91 at -110 odds. The implied probability for San Francisco Giants is 52.38%.
  • Chicago Cubs bettors risk $100 to win $90.91 at -110 odds. The implied probability for Chicago Cubs is 52.38%.

Chicago Cubs at San Francisco Giants Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cubs
Giants
First Team to Score
8/28/25 3:45pm EDT
-145+110Bet
Cubs
Giants
Tie
1st Inning Winner
8/28/25 3:45pm EDT
+360+360-185Bet
Cubs
Giants
Tie
First 3 Innings Winner
8/28/25 3:45pm EDT
+165+154+210Bet
Cubs
Giants
To Extra Innings
8/28/25 3:45pm EDT
Yes +675No -1100Bet
BetMGM Sports Betting BetMGM
Cubs
Giants
1st Team to Score Will Win
8/28/25 3:45pm EDT
Yes -250No +190Bet
Cubs
Total Runs
CUB at SFO
8/28/25 3:45pm EDT
3.5 o -1183.5 u -110Bet
Giants
Total Runs
CUB at SFO
8/28/25 3:45pm EDT
3.5 o -1053.5 u -125Bet
Logan Webb
Strikeouts Thrown
CUB at SFO
8/28/25 3:45pm EDT
5.5 o -1185.5 u -110Bet
BetMGM Sports Betting BetMGM
Shota Imanaga
Strikeouts Thrown
CUB at SFO
8/28/25 3:45pm EDT
5.5 o +1205.5 u -155Bet

Chicago Cubs & San Francisco Giants Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago Cubs World Series Odds
2025 Chicago Cubs World Series Odds

Team
BetMGM Sports Betting BetMGM
Cubs
+1600
Bet
San Francisco Giants World Series Odds
2025 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+50000
Bet

Chicago Cubs & San Francisco Giants Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Chicago Cubs, San Francisco Giants
Team W L Pct GB Home Away RS RA Diff Strk L10
Chicago Cubs79590.572+5.542-2537-34683565+118W16-4
San Francisco Giants69690.500+15.535-3434-35588571+17W28-2

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Chicago Cubs vs San Francisco Giants MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, August 28th, 2025 at 3:45 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Chicago Cubs vs San Francisco Giants Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago Cubs vs San Francisco Giants Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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