The Padres will play the Guardians on Saturday, March 7th, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Padres at Guardians Odds
| Underdog San Diego Padres | Favorite Cleveland Guardians |
|---|---|
| Over | Under |
|---|---|
| Underdog San Diego Padres | Favorite Cleveland Guardians |
|---|---|
Matchup Odds FAQs
The Cleveland Guardians are the -170 moneyline favorite at BetMGM and the San Diego Padres are the +145 moneyline underdog at BetMGM.
The best over line is 9.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 9.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The Cleveland Guardians are -1.5 +120 run line favorites at BetMGM, while the San Diego Padres are +1.5 -145 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Padres
Guardians
3/07/26 3:05pm EST | +145-170 |
- San Diego Padres bettors risk $100 to win $145 at +145 odds. The implied probability for San Diego Padres is 40.82%.
- Cleveland Guardians bettors risk $100 to win $58.82 at -170 odds. The implied probability for Cleveland Guardians is 62.96%.
San Diego Padres at Cleveland Guardians Prop Bets
| BetMGM Bet |
|
|---|---|
Padres
Guardians
3/07/26 3:05pm EST | Pending BetMGM |
San Diego Padres & Cleveland Guardians Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Diego Padres World Series Odds|
Team | BetMGM |
|---|---|
| Padres | +2800 Bet |
|
Team | BetMGM |
|---|---|
| Guardians | +5000 Bet |
San Diego Padres & Cleveland Guardians Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cleveland Guardians | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0 | 0 | 0 | - | 0 |
| San Diego Padres | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0 | 0 | 0 | - | 0 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Diego Padres vs Cleveland Guardians MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, March 7th, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Diego Padres vs Cleveland Guardians Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Cleveland Guardians Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 7, 2026 MLB Games
- Miami Marlins vs Houston Astros - 3/07/26 12:05pm EST
- Tampa Bay Rays vs Boston Red Sox - 3/07/26 1:05pm EST
- Pittsburgh Pirates vs Detroit Tigers - 3/07/26 1:05pm EST
- Toronto Blue Jays vs Philadelphia Phillies - 3/07/26 1:05pm EST
- New York Mets vs St. Louis Cardinals - 3/07/26 1:05pm EST
- Cincinnati Reds vs Kansas City Royals - 3/07/26 3:05pm EST
- Chicago White Sox vs Seattle Mariners - 3/07/26 3:10pm EST
- New York Yankees vs Washington Nationals - 3/07/26 6:05pm EST
- Colorado Rockies vs Los Angeles Dodgers - 3/07/26 8:05pm EST