DePaul vs Villanova Basketball Odds

The Blue Demons will play the Wildcats on Wednesday, December 31st, 2025. Your timezone's tip off time is 6:00 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

Looking into the second half of the 2025-26 college basketball season, DePaul and Villanova are set to hit the hardwood on Wednesday, December 31st, 2025. Luckily, we have some clear performance trends emerging now that each team has more than a dozen games under their belts. Use the following data to help analyze this matchup and to place an intelligent wager on its ultimate outcome.

  • SportsBetting3.com Power Rankings - With the 2025-26 season in full stride, DePaul currently has a 95.33 conference power ranking, while the SportsBetting3.com conference power ranking for Villanova is 98.67.
  • Away DePaul - DePaul starts this game with a 1-1 record as an away team, ranking them 2nd in the Big East Conference for away team wins.
  • Home Villanova - Villanova meets DePaul boasting a 7-0 record as a home team. They currently rank 1st in the Big East Conference for home team wins.
  • Conference Win Percentage - DePaul currently ranks 3rd (0.000) in the Big East Conference, with Villanova now standing 1st (1.000) for their conference win percentage in the 2025 Big East Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - DePaul has a 0.615 overall win percentage, with Villanova matching up with a 0.833 overall win percentage.
  • Team Records - DePaul currently possesses 8-5 regular season overall record. Meanwhile, Villanova has tallied a 10-2 standing as the 2025-26 college basketball season continues to unfold.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus! DePaul with 8-5 faces Villanova with 10-2 on Wednesday.

Conference records crucial for tournament seeds. DePaul 0-2, Villanova 1-0 in Big East.

DePaul lost last 2, Villanova won last 3. Magical match-up ahead! Review the tables below to find the best point spread, total, and moneylines for this game. You can bet on college basketball legally at BetRivers and BetMGM. We've also listed each team's futures odds and current standings below. Let the wizardry of basketball begin!

Best Blue Demons at Wildcats Odds


Best Point Spread Betting Odds
Underdog

DePaul
Favorite

Villanova
Villanova has a -12.5 -118 point spread at BetRivers PA. They are the point spread favorite in this matchup. DePaul has a +12.5 -106 point spread at BetRivers PA. DePaul is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
Total odds are updating, please check back soon.

Best Moneyline Betting Odds
Underdog

DePaul
Favorite

Villanova
Villanova is the -910 moneyline favorite. Risk $910 to win $100 on Villanova at BetRivers. DePaul is the +510 underdog at BetRivers. Risk $100 to win $510 on DePaul. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the DePaul vs Villanova College Basketball game on Wednesday, December 31st, 2025?

Villanova is a -12.5 -118 point spread favorite at BetRivers, while DePaul is a +12.5 -106 point spread underdog at BetRivers.

What is the moneyline for the DePaul vs Villanova College Basketball game on Wednesday, December 31st, 2025?

Villanova is a -910 moneyline favorite at BetRivers and DePaul is a +510 moneyline underdog at BetRivers.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
DePaul
Villanova
12/31/25 6:00pm EST
+12.5 -106-12.5 -118
Bet $100 at BetRivers Pennsylvania
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Underdog DePaul - DePaul bettors risk $100 to win $94.34 at -106 odds.

A +12.5 DePaul underdog bet wins if they lose by 12 or fewer, tie, or win outright. Your bet loses if they lose by 13 or more.

Favorite Villanova - Villanova bettors risk $100 to win $84.75 at -118 odds.

A -12.5 Villanova favorite bet wins if they win by 13 or more. Your bet loses if they win by 12 or fewer, tie, or lose outright.

DePaul at Villanova Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
DePaul
Villanova
12/31/25 6:00pm EST
Pending BetMGM

Team Standings

2025-2026 College Basketball Regular Season Standings - DePaul, Villanova
Team W-L Win% Home Away Conf CGB Conf% Strk
Villanova21-50.80812-28-212-3+20.800W6
DePaul13-120.52011-41-75-9+8.50.357W1

DePaul & Villanova Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

DePaul Championship Odds
2025-26 DePaul NCAA Men's Basketball Tournament Odds

Team
BetRivers Sports Betting BetRivers
DePaul
+50000
Bet
Villanova Championship Odds
2025-26 Villanova NCAA Men's Basketball Tournament Odds

Team
BetRivers Sports Betting BetRivers
Villanova
+20000
Bet

DePaul & Villanova Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the DePaul vs Villanova College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, December 31st, 2025 at 6:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the DePaul vs Villanova Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the DePaul vs Villanova Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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