Louisville vs Indiana Basketball Odds

The Cardinals will play the Hoosiers on Saturday, December 6th, 2025. Your timezone's tip off time is 2:15 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

The Louisville and Indiana basketball teams will play on Saturday, December 6th, 2025 as the 2025-26 college basketball season continues to roll along. Now that both teams have a few games under their belts, let’s size up this matchup by looking at some performance metrics and key stats.

  • SportsBetting3.com Power Rankings - Louisville currently has a 97.67 conference power ranking so far in the 2025-26 season. The SportsBetting3.com conference power ranking for Indiana is 97.33.
  • Away Louisville - Louisville heads into this game with a 0-1 record as an away team, ranking them 2nd in the ACC Conference for away team wins.
  • Home Indiana - Indiana will host Louisville sporting a 6-0 record as a home team. They currently rank 1st in the Big Ten Conference for home team wins for the 2025-26 season.
  • Conference Win Percentage - Louisville currently ranks 1st (0.000) in the ACC Conference, with Indiana now standing 2nd (0.000) for their conference win percentage in the 2025 Big Ten Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - Louisville has a 0.875 overall win percentage. Their opponent, Indiana, has a 0.875 overall win percentage.
  • Team Records - Louisville has a 7-1 regular season overall record. Indiana has notched a 7-1 standing so far in the 2025-26 college basketball season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus! Louisville and Indiana clash in magical basketball showdown!

Both teams 7-1, battling for conference tournament seedings. Louisville 0-0, Indiana 0-1 conference record.

Louisville and Indiana seek redemption after recent losses. Our point spread, total, and moneyline tables show the best lines and odds for this matchup. Place a bet at BetMGM or BetRivers and witness the wizardry on the court. Review each team’s futures odds and current standings below.

Best Cardinals at Hoosiers Odds


Best Point Spread Betting Odds
Underdog

Indiana
Favorite

Louisville
Louisville has a -3.5 -114 point spread at BetRivers PA. They are the point spread favorite in this matchup. Indiana has a +3.5 -109 point spread at BetRivers PA. Indiana is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 160.5 points. Risk $114 to win $100. BetRivers has the best under line of 160.5 points. Risk $109 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Indiana
Favorite

Louisville
Louisville is the -177 moneyline favorite. Risk $177 to win $100 on Louisville at BetRivers. Indiana is the +132 underdog at BetRivers. Risk $100 to win $132 on Indiana. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Louisville vs Indiana College Basketball game on Saturday, December 6th, 2025?

Louisville is a -3.5 -114 point spread favorite at BetRivers, while Indiana is a +3.5 -109 point spread underdog at BetRivers.

What is the over-under total line for the Louisville vs Indiana College Basketball game on Saturday, December 6th, 2025?

The best over line is 160.5 -114 points at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 160.5 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.

What is the moneyline for the Louisville vs Indiana College Basketball game on Saturday, December 6th, 2025?

Louisville is a -177 moneyline favorite at BetRivers and Indiana is a +132 moneyline underdog at BetRivers.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Louisville
Indiana
12/06/25 2:15pm EST
-3.5 -114+3.5 -109
Bet $100 at BetRivers Pennsylvania
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Underdog Indiana - Indiana bettors risk $100 to win $91.74 at -109 odds.

A +3.5 Indiana underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite Louisville - Louisville bettors risk $100 to win $87.72 at -114 odds.

A -3.5 Louisville favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

Louisville at Indiana Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Louisville
Indiana
12/06/25 2:15pm EST
Pending BetMGM

Team Standings

2025-2026 College Basketball Regular Season Standings - Louisville, Indiana
Team W-L Win% Home Away Conf CGB Conf% Strk
ACC
#11 Louisville8-10.8896-00-10-0-0.000W1
Big Ten
Indiana7-20.7786-00-10-1+1.50.000L2

Louisville & Indiana Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Louisville Championship Odds
2025-26 Louisville NCAA Men's Basketball Tournament Odds

Team
BetRivers Sports Betting BetRivers
Louisville
+1600
Bet
Indiana Championship Odds
2025-26 Indiana NCAA Men's Basketball Tournament Odds

Team
BetRivers Sports Betting BetRivers
Indiana
+10000
Bet

Louisville & Indiana Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Louisville vs Indiana College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, December 6th, 2025 at 2:15 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Louisville vs Indiana Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Louisville vs Indiana Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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