Michigan vs USC Football Odds

The Wolverines will play the Trojans on Saturday, October 11th, 2025. The matchup takes place at Los Angeles Memorial Coliseum. Watch this exciting Week 7 matchup at 7:30 pm EDT. Check local listings for coverage on NBC.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Key Matchup Stats

We're now well into the 2025 college football season. Week 7 action features a matchup between Michigan and USC taking place at Los Angeles Memorial Coliseum. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Michigan has a 96.67 conference power ranking for the 2025 season. The conference power ranking for USC is 96.67.
  • Away Michigan - Heading into Week 7, Michigan currently has a 1-1 record as an away team for the 2025 regular season. This ranks them 2nd in the Big Ten Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home USC - USC has a 3-0 record as a home team. Looking ahead to this 2025 Week 7 matchup, they rank 2nd in the Big Ten Conference for home team wins. Like the Michigan away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2025 season, Michigan ranks 10th (164) in the Big Ten Conference, with USC currently ranking 1st (242) for points scored in the Big Ten Conference.
  • Points Against - Also in 2025, Michigan stands 11th (81) in the Big Ten Conference for points scored by opponents in 2025. USC sits at 6th (115) in the Big Ten Conference for points against in the 2025 season so far.
  • Team Records - Michigan has a 4-1 overall record for the 2025 regular season, with USC currently 4-1 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Paddy O'Parlay
Paddy O'Parlay

Oh, lads and lasses, it's Michigan versus USC in a clash of college football titans!

This Week 7 showdown will take place at the historic Los Angeles Memorial Coliseum.

The SportsBetting3.com Power Rankings have both teams tied at a mighty 96.67 rating.

Michigan comes in with a 4-1 record, while USC also boasts a 4-1 standing.

So grab your lucky charms, bet this game at BetRivers, or BetMGM, and review this game's prop bets before comparing the odds below!

Best Wolverines at Trojans Odds


Best Point Spread Betting Odds
Underdog

Michigan
Favorite

USC
USC has a -2.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Michigan has a +2.5 -105 point spread at BetMGM OH. Michigan is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 56.5 points. Risk $110 to win $100. BetMGM has the best under line of 56.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Michigan
Favorite

USC
USC is the -140 moneyline favorite. Risk $140 to win $100 on USC at BetMGM. Michigan is the +115 underdog at BetMGM. Risk $100 to win $115 on Michigan. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

USC is a -2.5 -115 point spread favorite at BetMGM, while Michigan is a +2.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

The best over line is 56.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 56.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

USC is a -140 moneyline favorite at BetMGM and Michigan is a +115 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Michigan
USC
10/11/25 7:30pm EDT
+2.5 -105-2.5 -115
Bet $100 at BetMGM Ohio
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Underdog Michigan - Michigan bettors risk $100 to win $95.24 at -105 odds.

A +2.5 Michigan underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite USC - USC bettors risk $100 to win $86.96 at -115 odds.

A -2.5 USC favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Michigan at USC Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Michigan
USC
No Touchdown
To Score 1st Touchdown
10/11/25 7:30pm EDT
+105-150+10000Bet
Michigan
USC
Game to Overtime
10/11/25 7:30pm EDT
Yes +950No -5000Bet
Michigan
USC
Both Teams Score 10+
10/11/25 7:30pm EDT
Yes -2500No +900Bet
Michigan
USC
Both Teams Score 20+
10/11/25 7:30pm EDT
Yes -210No +160Bet
BetMGM Sports Betting BetMGM
Michigan
USC
Both Teams Score 30+
10/11/25 7:30pm EDT
Yes +280No -375Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 7
Michigan vs USC
Saturday, October 11th, 2025
USC 31, MICH 13
Los Angeles Memorial Coliseum
USC by 18
2024
Week 4
USC vs Michigan
Saturday, September 21st, 2024
MICH 27, USC 24
Michigan Stadium
Michigan by 3

Team Standings

2025-2026 College Football Regular Season Standings - Michigan, USC
Team Conf Conf% W L PF PA Home Away Strk
USC3-10.750512731284-01-1W1
#15 Michigan2-10.667421771123-01-2L1

Michigan & USC Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Michigan Championship Odds
2025-26 Michigan NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
Michigan
+8000
Bet
USC Championship Odds
2025-26 USC NCAA College Football Championship Odds

Team
BetMGM Sports Betting BetMGM
USC
+8000
Bet

Michigan & USC Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Michigan Games & Results
WeekMatchupDate & Result
Week 1New Mexico vs
Michigan
MICH 34, UNM 17
Saturday, August 30th, 2025
Week 2Michigan vs
Oklahoma
OU 24, MICH 13
Saturday, September 6th, 2025
Week 3Central Michigan vs
Michigan
MICH 63, CMU 3
Saturday, September 13th, 2025
Week 4Michigan vs
Nebraska
MICH 30, NEB 27
Saturday, September 20th, 2025
Week 6Wisconsin vs
Michigan
MICH 24, WIS 10
Saturday, October 4th, 2025
Week 7Michigan vs
USC
USC 31, MICH 13
Saturday, October 11th, 2025
Week 8Washington vs
Michigan
Saturday, October 18th, 2025
12:00 pm EDT
Week 9Michigan vs
Michigan State
Saturday, October 25th, 2025
12:00 am EDT
Week 10Purdue vs
Michigan
Saturday, November 1st, 2025
12:00 am EDT
Week 12Michigan vs
Northwestern
Saturday, November 15th, 2025
12:00 am EST
Week 13Michigan vs
Maryland
Saturday, November 22nd, 2025
12:00 am EST
Week 14Ohio State vs
Michigan
Saturday, November 29th, 2025
12:00 pm EST


2025-26 USC Games & Results
WeekMatchupDate & Result
Week 1Missouri State vs
USC
USC 73, MOST 13
Saturday, August 30th, 2025
Week 2Georgia Southern vs
USC
USC 59, GASO 20
Saturday, September 6th, 2025
Week 3USC vs
Purdue
USC 33, PUR 17
Saturday, September 13th, 2025
Week 4Michigan State vs
USC
USC 45, MSU 31
Saturday, September 20th, 2025
Week 5USC vs
Illinois
ILL 34, USC 32
Saturday, September 27th, 2025
Week 7Michigan vs
USC
USC 31, MICH 13
Saturday, October 11th, 2025
Week 8USC vs
Notre Dame
Saturday, October 18th, 2025
7:30 pm EDT
Week 10USC vs
Nebraska
Saturday, November 1st, 2025
12:00 am EDT
Week 11Northwestern vs
USC
Friday, November 7th, 2025
9:00 pm EST
Week 12Iowa vs
USC
Saturday, November 15th, 2025
12:00 am EST
Week 13USC vs
Oregon
Saturday, November 22nd, 2025
12:00 am EST
Week 14UCLA vs
USC
Saturday, November 29th, 2025
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Michigan vs USC College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 11th, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Michigan vs USC Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Michigan vs USC Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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