Michigan vs USC Football Odds - SportsBetting3.com

The Wolverines will play the Trojans on Saturday, October 11th, 2025. The matchup takes place at Los Angeles Memorial Coliseum. Watch this exciting Week 7 matchup at 7:30 pm EDT. Check local listings for coverage on NBC.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Key Matchup Stats

We're now well into the 2025 college football season. Week 7 action features a matchup between Michigan and USC taking place at Los Angeles Memorial Coliseum. The following are some key season stats to help you size up this game.

SportsBetting3.com Power Rankings - Michigan has a 96.67 conference power ranking for the 2025 season. The conference power ranking for USC is 96.67.
Away Michigan - Heading into Week 7, Michigan currently has a 1-1 record as an away team for the 2025 regular season. This ranks them 2nd in the Big Ten Conference for away team wins. Watch this stat carefully as the season progresses.
Home USC - USC has a 3-0 record as a home team. Looking ahead to this 2025 Week 7 matchup, they rank 2nd in the Big Ten Conference for home team wins. Like the Michigan away record and ranking, you should continually keep tabs on this stat.
Points Scored - For the 2025 season, Michigan ranks 10th (164) in the Big Ten Conference, with USC currently ranking 1st (242) for points scored in the Big Ten Conference.
Points Against - Also in 2025, Michigan stands 11th (81) in the Big Ten Conference for points scored by opponents in 2025. USC sits at 6th (115) in the Big Ten Conference for points against in the 2025 season so far.
Team Records - Michigan has a 4-1 overall record for the 2025 regular season, with USC currently 4-1 for the 2025 NCAAF regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Oh, lads and lasses, it's Michigan versus USC in a clash of college football titans!

This Week 7 showdown will take place at the historic Los Angeles Memorial Coliseum.

The SportsBetting3.com Power Rankings have both teams tied at a mighty 96.67 rating.

Michigan comes in with a 4-1 record, while USC also boasts a 4-1 standing.

So grab your lucky charms, bet this game at BetRivers, or BetMGM, and review this game's prop bets before comparing the odds below!

Best Wolverines at Trojans Odds

**Best Point Spread Betting Odds**
Underdog Michigan	Favorite USC
+2.5 -105 BetMGM Bet	-2.5 -115 BetMGM Bet

USC has a -2.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Michigan has a +2.5 -105 point spread at BetMGM OH. Michigan is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
56.5 o -110 BetMGM Bet	56.5 u -110 BetMGM Bet

BetMGM has the best over line of 56.5 points. Risk $110 to win $100. BetMGM has the best under line of 56.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Michigan	Favorite USC
+115 BetMGM Bet	-140 BetMGM Bet

USC is the -140 moneyline favorite. Risk $140 to win $100 on USC at BetMGM. Michigan is the +115 underdog at BetMGM. Risk $100 to win $115 on Michigan. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

USC is a -2.5 -115 point spread favorite at BetMGM, while Michigan is a +2.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

The best over line is 56.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 56.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Michigan vs USC College Football game on Saturday, October 11th, 2025?

USC is a -140 moneyline favorite at BetMGM and Michigan is a +115 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Michigan USC 10/11/25 7:30pm EDT	+2.5 -105 -2.5 -115

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Underdog Michigan - Michigan bettors risk $100 to win $95.24 at -105 odds.

A +2.5 Michigan underdog bet wins if they lose by 2 or fewer, tie, or win outright. Your bet loses if they lose by 3 or more.

Favorite USC - USC bettors risk $100 to win $86.96 at -115 odds.

A -2.5 USC favorite bet wins if they win by 3 or more. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Michigan at USC Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Michigan USC No Touchdown To Score 1st Touchdown 10/11/25 7:30pm EDT	+105 -150 +10000 Bet
Michigan USC Game to Overtime 10/11/25 7:30pm EDT	Yes +950 No -5000 Bet
Michigan USC Both Teams Score 10+ 10/11/25 7:30pm EDT	Yes -2500 No +900 Bet
Michigan USC Both Teams Score 20+ 10/11/25 7:30pm EDT	Yes -210 No +160 Bet
	BetMGM
Michigan USC Both Teams Score 30+ 10/11/25 7:30pm EDT	Yes +280 No -375 Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
Week	Game	Result	Margin
2025 Week 7	Michigan vs USC Saturday, October 11th, 2025	USC 31, MICH 13 Los Angeles Memorial Coliseum	USC by 18
2024 Week 4	USC vs Michigan Saturday, September 21st, 2024	MICH 27, USC 24 Michigan Stadium	Michigan by 3

Team Standings

2025-2026 College Football Regular Season Standings - Michigan, USC
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
#15 Michigan	7-1	0.875	9	2	322	197	5-0	4-2	W5
#17 USC	6-2	0.750	8	3	409	259	6-0	2-3	L1

Michigan & USC Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Michigan Championship Odds

2025-26 Michigan NCAA College Football Championship Odds
Team	BetMGM
Michigan	+8000 Bet

USC Championship Odds

2025-26 USC NCAA College Football Championship Odds
Team	BetMGM
USC

Michigan & USC Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2025-26 Michigan Games & Results
Week	Matchup	Date & Result
Week 1	New Mexico vs Michigan	MICH 34, UNM 17 Saturday, August 30th, 2025
Week 2	Michigan vs Oklahoma	OU 24, MICH 13 Saturday, September 6th, 2025
Week 3	Central Michigan vs Michigan	MICH 63, CMU 3 Saturday, September 13th, 2025
Week 4	Michigan vs Nebraska	MICH 30, NEB 27 Saturday, September 20th, 2025
Week 6	Wisconsin vs Michigan	MICH 24, WIS 10 Saturday, October 4th, 2025
Week 7	Michigan vs USC	USC 31, MICH 13 Saturday, October 11th, 2025
Week 8	Washington vs Michigan	MICH 24, WASH 7 Saturday, October 18th, 2025
Week 9	Michigan vs Michigan State	Saturday, October 25th, 2025 7:30 pm EDT
Week 10	Purdue vs Michigan	Saturday, November 1st, 2025 7:00 pm EDT
Week 12	Michigan vs Northwestern	Saturday, November 15th, 2025 12:00 am EST
Week 13	Michigan vs Maryland	Saturday, November 22nd, 2025 12:00 am EST
Week 14	Ohio State vs Michigan	Saturday, November 29th, 2025 12:00 pm EST

2025-26 USC Games & Results
Week	Matchup	Date & Result
Week 1	Missouri State vs USC	USC 73, MOST 13 Saturday, August 30th, 2025
Week 2	Georgia Southern vs USC	USC 59, GASO 20 Saturday, September 6th, 2025
Week 3	USC vs Purdue	USC 33, PUR 17 Saturday, September 13th, 2025
Week 4	Michigan State vs USC	USC 45, MSU 31 Saturday, September 20th, 2025
Week 5	USC vs Illinois	ILL 34, USC 32 Saturday, September 27th, 2025
Week 7	Michigan vs USC	USC 31, MICH 13 Saturday, October 11th, 2025
Week 8	USC vs Notre Dame	ND 34, USC 24 Saturday, October 18th, 2025
Week 10	USC vs Nebraska	Saturday, November 1st, 2025 7:30 pm EDT
Week 11	Northwestern vs USC	Friday, November 7th, 2025 9:00 pm EST
Week 12	Iowa vs USC	Saturday, November 15th, 2025 12:00 am EST
Week 13	USC vs Oregon	Saturday, November 22nd, 2025 12:00 am EST
Week 14	UCLA vs USC	Saturday, November 29th, 2025 12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Michigan vs USC College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, October 11th, 2025 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Michigan vs USC Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Michigan vs USC Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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