The Bulls will play the Cardinals on Saturday, September 24th, 2022. The matchup takes place at Cardinal Stadium. Watch this exciting Week 4 matchup at 12:00 pm EDT. Check local listings for coverage on ESPN3.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Schedules & Results
- Other Games Today
Best Bulls at Cardinals Odds
| Underdog South Florida | Favorite Louisville |
|---|---|
| Over | Under |
|---|---|
| Underdog South Florida | Favorite Louisville |
|---|---|
Matchup Odds FAQs
Louisville is a -14.5 -112 point spread favorite at BetRivers, while South Florida is a +14.5 -109 point spread underdog at BetRivers.
The best over line is 63 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 63 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.
Louisville is a -715 moneyline favorite at BetRivers and South Florida is a +430 moneyline underdog at BetRivers.
College Football Odds Example
|
Game |
 BetRiversBet |
|---|---|
South Florida
Louisville
9/24/22 12:00pm EDT | +14.5 -109-14.5 -112 |
Underdog South Florida - South Florida bettors risk $100 to win $91.74 at -109 odds.
A +14.5 South Florida underdog bet wins if they lose by 14 or fewer, tie, or win outright. Your bet loses if they lose by 15 or more.
Favorite Louisville - Louisville bettors risk $100 to win $89.29 at -112 odds.
A -14.5 Louisville favorite bet wins if they win by 15 or more. Your bet loses if they win by 14 or fewer, tie, or lose outright.
South Florida at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
 BetMGMBet |
|
|---|---|
South Florida
Louisville
9/24/22 12:00pm EDT | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2022 Week 4 | South Florida vs Louisville Saturday, September 24th, 2022 | LOU 41, USF 3 Cardinal Stadium | Louisville by 38 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| American | |||||||||
| South Florida | 0-8 | 0.000 | 1 | 11 | 336 | 494 | 1-4 | 0-6 | L10 |
| ACC Atlantic | |||||||||
| Louisville | 4-4 | 0.500 | 8 | 5 | 350 | 249 | 5-1 | 2-4 | W1 |
South Florida & Louisville Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
South Florida Championship Odds|
Team | BetMGM |
BetRivers |
|---|---|---|
| South Florida | +100000 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Louisville | +10000 Bet | +10000 Bet |
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | BYU vs South Florida | BYU 50, USF 21 Saturday, September 3rd, 2022 |
| Week 2 | Howard vs South Florida | USF 42, HOW 20 Saturday, September 10th, 2022 |
| Week 3 | South Florida vs Florida | FLA 31, USF 28 Saturday, September 17th, 2022 |
| Week 4 | South Florida vs Louisville | LOU 41, USF 3 Saturday, September 24th, 2022 |
| Week 5 | East Carolina vs South Florida | ECU 48, USF 28 Saturday, October 1st, 2022 |
| Week 6 | South Florida vs Cincinnati | CIN 28, USF 24 Saturday, October 8th, 2022 |
| Week 7 | Tulane vs South Florida | TULN 45, USF 31 Saturday, October 15th, 2022 |
| Week 9 | South Florida vs Houston | HOU 42, USF 27 Saturday, October 29th, 2022 |
| Week 10 | South Florida vs Temple | TEM 54, USF 28 Saturday, November 5th, 2022 |
| Week 11 | SMU vs South Florida | SMU 41, USF 23 Saturday, November 12th, 2022 |
| Week 12 | South Florida vs Tulsa | TLSA 48, USF 42 Friday, November 18th, 2022 |
| Week 13 | UCF vs South Florida | UCF 46, USF 39 Saturday, November 26th, 2022 |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Louisville vs Syracuse | SYR 31, LOU 7 Saturday, September 3rd, 2022 |
| Week 2 | Louisville vs UCF | LOU 20, UCF 14 Friday, September 9th, 2022 |
| Week 3 | Florida State vs Louisville | FSU 35, LOU 31 Friday, September 16th, 2022 |
| Week 4 | South Florida vs Louisville | LOU 41, USF 3 Saturday, September 24th, 2022 |
| Week 5 | Louisville vs Boston College | BC 34, LOU 33 Saturday, October 1st, 2022 |
| Week 6 | Louisville vs Virginia | LOU 34, UVA 17 Saturday, October 8th, 2022 |
| Week 8 | Pittsburgh vs Louisville | LOU 24, PITT 10 Saturday, October 22nd, 2022 |
| Week 9 | Wake Forest vs Louisville | LOU 48, WAKE 21 Saturday, October 29th, 2022 |
| Week 10 | James Madison vs Louisville | LOU 34, JMU 10 Saturday, November 5th, 2022 |
| Week 11 | Louisville vs Clemson | CLEM 31, LOU 16 Saturday, November 12th, 2022 |
| Week 12 | NC State vs Louisville | LOU 25, NCST 10 Saturday, November 19th, 2022 |
| Week 13 | Louisville vs Kentucky | UK 26, LOU 13 Saturday, November 26th, 2022 |
| Bowls | Cincinnati vs Louisville Wasabi Fenway Bowl | LOU 24, CIN 7 Saturday, December 17th, 2022 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the South Florida vs Louisville College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 24th, 2022 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the South Florida vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the South Florida vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.