The Cardinals will play the Saints on Sunday, September 7th, 2025. The matchup takes place at Caesars Superdome. Watch this exciting Week 1 matchup at 1:00 pm EDT. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
It's early in the 2025-26 NFL regular season for the Arizona Cardinals and New Orleans Saints. Let's review some stats from the 2024 regular season to get an idea of how these teams will fare.
- SportsBetting3.com Power Rankings - The Arizona Cardinals had a 92.33 power ranking in the 2024 regular season. The power ranking for the New Orleans Saints in the 2024 regular season was 88.00.
- Away Arizona Cardinals - At the end of the 2024 regular season, the Arizona Cardinals had a 2-6-0 record as an away team, ranking them 7th in the regular season for away team wins.
- Home New Orleans Saints - The New Orleans Saints finished the 2024 regular season with a 3-6-0 record as a home team. They ranked 6th for home team wins in the regular season standings.
- Points Scored - The Arizona Cardinals wound up 12th (400) in the regular season, with the New Orleans Saints ranked 23rd (338) for points scored in the 2024 regular season.
- Points Against - The Arizona Cardinals finished 16th (379) in the regular season for points against. The New Orleans Saints wound up 12th (398) in the 2024 regular season for points against.
- Team Records - The Arizona Cardinals had a 8-9-0 regular season record, with the New Orleans Saints notching a 5-12-0 regular season standing last year.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Cardinals be takin' on the Saints at Caesars Superdome. Last season's records be forgettable, but this battle be worth watchin'!
The Cardinals be lookin' to start strong on the road. The Saints be seekin' redemption in front of their loyal crew. SportsBetting3.com be where ye can bet on this game. Be sure to review the odds below before settin' sail on this NFL showdown!
Best Cardinals at Saints Odds
| Underdog New Orleans Saints | Favorite Arizona Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog New Orleans Saints | Favorite Arizona Cardinals |
|---|---|
Matchup Odds FAQs
The Arizona Cardinals are -6.5 -105 point spread favorites at BetMGM, while the New Orleans Saints are +6.5 -115 point spread underdogs at BetMGM.
The best over line is 44.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 44.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.
The Arizona Cardinals are the -300 moneyline favorite at BetMGM and the New Orleans Saints are the +240 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cardinals
Saints
9/07/25 1:00pm EDT | -6.5 -105+6.5 -115 |
Underdog New Orleans Saints - New Orleans Saints bettors risk $100 to win $86.96 at -115 odds.
A +6.5 New Orleans Saints underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $95.24 at -105 odds.
A -6.5 Arizona Cardinals favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
Arizona Cardinals at New Orleans Saints Prop Bets
| BetMGM Bet |
|
|---|---|
Cardinals
Saints
First Team To Score
9/07/25 1:00pm EDT | -160+125Bet |
Cardinals
Saints
No Touchdown
To Score 1st Touchdown
9/07/25 1:00pm EDT | -190+140+10000Bet |
Cardinals
Saints
Game to Overtime
9/07/25 1:00pm EDT | Yes +775No -2500Bet |
Cardinals
Saints
Safety to be Scored
9/07/25 1:00pm EDT | Yes +1000No -3000Bet |
| BetMGM | |
Kyler Murray
Interceptions Thrown
ARI at NO 9/07/25 1:00pm EDT | 0.5 o -1100.5 u -118Bet |
Spencer Rattler
Interceptions Thrown
ARI at NO 9/07/25 1:00pm EDT | 0.5 o -1900.5 u +145Bet |
Kyler Murray
Longest Passing Completion
ARI at NO 9/07/25 1:00pm EDT | 34.5 o -12034.5 u -110Bet |
Spencer Rattler
Longest Passing Completion
ARI at NO 9/07/25 1:00pm EDT | 31.5 o -11831.5 u -110Bet |
| BetMGM | |
Blake Grupe
Total Kicking Points
ARI at NO 9/07/25 1:00pm EDT | 6.5 o +1006.5 u -135Bet |
Chad Ryland
Total Kicking Points
ARI at NO 9/07/25 1:00pm EDT | 7.5 o -1157.5 u -115Bet |
Kyler Murray
Total Pass Completions
ARI at NO 9/07/25 1:00pm EDT | 20.5 o -13520.5 u +105Bet |
Spencer Rattler
Total Pass Completions
ARI at NO 9/07/25 1:00pm EDT | 18.5 o -12518.5 u -105Bet |
| BetMGM | |
Kyler Murray
Total Passing Yards
ARI at NO 9/07/25 1:00pm EDT | 225.5 o -105225.5 u -125Bet |
Spencer Rattler
Total Passing Yards
ARI at NO 9/07/25 1:00pm EDT | 195.5 o -115195.5 u -115Bet |
Kyler Murray
Total Touchdown Passes
ARI at NO 9/07/25 1:00pm EDT | 1.5 o +1001.5 u -130Bet |
Spencer Rattler
Total Touchdown Passes
ARI at NO 9/07/25 1:00pm EDT | 1.5 o +2001.5 u -275Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 1 | Cardinals vs Saints Sunday, September 7th, 2025 | ARI 20, NO 13 Caesars Superdome | Cardinals by 7 |
| 2024 Preseason Week 1 | Saints vs Cardinals Saturday, August 10th, 2024 | NO 16, ARI 14 State Farm Stadium | Saints by 2 |
| 2022 Week 7 | Saints vs Cardinals Thursday, October 20th, 2022 | ARI 42, NO 34 State Farm Stadium | Cardinals by 8 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arizona Cardinals | 2 | 0 | 0 | 1.000 | 47 | 35 | 1-0-0 | 1-0-0 | 0-0-0 | 0.000 | 2-0-0 | 1.000 | 2W | 2-0-0 |
| New Orleans Saints | 0 | 2 | 0 | 0.000 | 34 | 46 | 0-2-0 | 0-0-0 | 0-0-0 | 0.000 | 0-2-0 | 0.000 | 2L | 0-2-0 |
Arizona Cardinals & New Orleans Saints Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Arizona Cardinals Futures Odds|
Team | BetMGM |
|---|---|
| Cardinals | +5000 Bet |
|
Team | BetMGM |
|---|---|
| Saints | +75000 Bet |
Arizona Cardinals & New Orleans Saints Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Arizona Cardinals vs New Orleans Saints NFL Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 7th, 2025 at 1:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's NFL page, look for the Arizona Cardinals vs New Orleans Saints Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Arizona Cardinals vs New Orleans Saints Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 7, 2025 NFL Games
- Tampa Bay Buccaneers vs Atlanta Falcons - 9/07/25 1:00pm EDT
- Pittsburgh Steelers vs New York Jets - 9/07/25 1:00pm EDT
- Las Vegas Raiders vs New England Patriots - 9/07/25 1:00pm EDT
- Carolina Panthers vs Jacksonville Jaguars - 9/07/25 1:00pm EDT
- Cincinnati Bengals vs Cleveland Browns - 9/07/25 1:00pm EDT
- Miami Dolphins vs Indianapolis Colts - 9/07/25 1:03pm EDT
- New York Giants vs Washington Commanders - 9/07/25 1:03pm EDT
- Tennessee Titans vs Denver Broncos - 9/07/25 4:05pm EDT
- San Francisco 49ers vs Seattle Seahawks - 9/07/25 4:05pm EDT
- Detroit Lions vs Green Bay Packers - 9/07/25 4:25pm EDT
- Houston Texans vs Los Angeles Rams - 9/07/25 4:25pm EDT
- Baltimore Ravens vs Buffalo Bills - 9/07/25 8:22pm EDT