The Rams will play the 49ers on Monday, October 3rd, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 4 matchup at 8:15 pm EDT. Check local listings for coverage on ESPN.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best Rams at 49ers Odds
| Underdog Los Angeles Rams | Favorite San Francisco 49ers |
|---|---|
| Over | Under |
|---|---|
| Underdog Los Angeles Rams | Favorite San Francisco 49ers |
|---|---|
Matchup Odds FAQs
The San Francisco 49ers are -2 -108 point spread favorites at BetRivers, while the Los Angeles Rams are +2 -110 point spread underdogs at BetMGM.
The best over line is 41.5 -113 points at BetRivers, which means you risk $113 to win $100 betting the over. The best under line is 42 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco 49ers are the -120 moneyline favorite at BetRivers and the Los Angeles Rams are the +110 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetRiversBet |
|---|---|
Rams
49ers
10/03/22 8:15pm EDT |
Underdog Los Angeles Rams - Los Angeles Rams bettors risk $100 to win $88.5 at -113 odds.
A +2 Los Angeles Rams underdog bet wins if they lose by 1, tie, or win outright. The bet pushes if they lose by 2. Your bet loses if they lose by 3 or more.
Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $92.59 at -108 odds.
A -2 San Francisco 49ers favorite bet wins if they win by 3 or more. The bet pushes if they win by 2. Your bet loses if they win by 1, tie, or lose outright.
Los Angeles Rams at San Francisco 49ers Prop Bets
| BetRivers Bet |
|
|---|---|
Rams
49ers
First Team To Score
10/03/22 8:15pm EDT | Bet |
Rams
49ers
Tie
First to 15 Points
10/03/22 8:15pm EDT | Bet |
Rams
49ers
Tie
First to 20 Points
10/03/22 8:15pm EDT | Bet |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2023 Week 2 | 49ers vs Rams Sunday, September 17th, 2023 | SF 30, LAR 23 SoFi Stadium | 49ers by 7 |
| 2022 Week 8 | 49ers vs Rams Sunday, October 30th, 2022 | SF 31, LAR 14 SoFi Stadium | 49ers by 17 |
| 2022 Week 4 | Rams vs 49ers Monday, October 3rd, 2022 | SF 24, LAR 9 Levi's Stadium | 49ers by 15 |
| 2021 Conference Championship | 49ers vs Rams Sunday, January 30th, 2022 NFC Championship | LAR 20, SF 17 SoFi Stadium | Rams by 3 |
| 2021 Week 18 | 49ers vs Rams Sunday, January 9th, 2022 | SF 27, LAR 24 (OT) SoFi Stadium | 49ers by 3 |
| 2021 Week 10 | Rams vs 49ers Monday, November 15th, 2021 | SF 31, LAR 10 Levi's Stadium | 49ers by 21 |
| 2020 Week 12 | 49ers vs Rams Sunday, November 29th, 2020 | SF 23, LAR 20 SoFi Stadium | 49ers by 3 |
| 2020 Week 6 | Rams vs 49ers Sunday, October 18th, 2020 | SF 24, LAR 16 Levi's Stadium | 49ers by 8 |
| 2019 Week 16 | Rams vs 49ers Saturday, December 21st, 2019 | SF 34, LAR 31 Levi's Stadium | 49ers by 3 |
| 2019 Week 6 | 49ers vs Rams Sunday, October 13th, 2019 | SF 20, LAR 7 Los Angeles Memorial Coliseum | 49ers by 13 |
| 2018 Week 17 | 49ers vs Rams Sunday, December 30th, 2018 | LAR 48, SF 32 Los Angeles Memorial Coliseum | Rams by 16 |
| 2018 Week 7 | Rams vs 49ers Sunday, October 21st, 2018 | LAR 39, SF 10 Levi's Stadium | Rams by 29 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz - San Francisco 49ers | 13 | 4 | 0 | 0.765 | 450 | 277 | 8-1-0 | 5-3-0 | 6-0-0 | 1.000 | 10-2-0 | 0.833 | 10W | 5-0-0 |
| Los Angeles Rams | 5 | 12 | 0 | 0.294 | 307 | 384 | 4-5-0 | 1-7-0 | 1-5-0 | 0.167 | 3-9-0 | 0.250 | 2L | 2-3-0 |
Los Angeles Rams & San Francisco 49ers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Los Angeles Rams Futures Odds|
Team | BetRivers |
 BetMGM |
|---|---|---|
| Rams |
|
Team | BetRivers |
BetMGM |
|---|---|---|
| 49ers |
Los Angeles Rams & San Francisco 49ers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Los Angeles Rams vs San Francisco 49ers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Monday, October 3rd, 2022 at 8:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Los Angeles Rams vs San Francisco 49ers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Los Angeles Rams vs San Francisco 49ers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other October 3, 2022 NFL Games
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