San Francisco 49ers vs Carolina Panthers Odds

The 49ers will play the Panthers on Sunday, October 9th, 2022. The matchup takes place at Bank of America Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


Bonus
BetWay Sportsbook#1 BetWay
REVIEW
New Customers - Bet $50, Get a $200 Bonus Bet
Bet Now
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500
BetRivers Sportsbook#2 BetRivers
REVIEW
New Customers - 2nd Chance Bet up to $500 - Code: SPORTS
Bet Now
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500
BetMGM Sportsbook#3 BetMGM
REVIEW
New Customers - Bet $5, Get $150 in Bonus Bets
Good Until Canceled
Bet Now
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500

Table of Contents

Best 49ers at Panthers Odds


Best Point Spread Betting Odds
Underdog

Carolina Panthers
Favorite

San Francisco 49ers
The San Francisco 49ers have a -6.5 -109 point spread at BetRivers VA. They are the point spread favorite in this matchup. The Carolina Panthers have a +6.5 -110 point spread at BetMGM. The Carolina Panthers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 40 points. Risk $109 to win $100. BetMGM has the best under line of 40 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Carolina Panthers
Favorite

San Francisco 49ers
The San Francisco 49ers are the -275 moneyline favorite. Risk $275 to win $100 on the San Francisco 49ers at BetRivers. The Carolina Panthers are the +235 underdog at BetRivers. Risk $100 to win $235 on the Carolina Panthers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The San Francisco 49ers are -6.5 -109 point spread favorites at BetRivers, while the Carolina Panthers are +6.5 -110 point spread underdogs at BetMGM.

What is the over-under total line for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The best over line is 40 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 40 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The San Francisco 49ers are the -275 moneyline favorite at BetRivers and the Carolina Panthers are the +235 moneyline underdog at BetRivers.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
49ers
Panthers
10/09/22 4:05pm EDT
Bet $100 at BetRivers Virginia
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500

Underdog Carolina Panthers - Carolina Panthers bettors risk $100 to win $89.29 at -112 odds.

A +6.5 Carolina Panthers underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $91.74 at -109 odds.

A -6.5 San Francisco 49ers favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.

San Francisco 49ers at Carolina Panthers Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
49ers
Panthers
First Team To Score
10/09/22 4:05pm EDT
Bet
49ers
Panthers
Tie
First to 15 Points
10/09/22 4:05pm EDT
Bet
49ers
Panthers
Tie
First to 20 Points
10/09/22 4:05pm EDT
Bet

Recent Meetings Since 2018

Recent Meetings Since 2018
WeekGameResultMargin
2022
Week 5
49ers vs Panthers
Sunday, October 9th, 2022
SF 37, CAR 15
Bank of America Stadium
49ers by 22
2019
Week 8
Panthers vs 49ers
Sunday, October 27th, 2019
SF 51, CAR 13
Levi's Stadium
49ers by 38

Team Standings

2022-2023 NFL Regular Season Standings - San Francisco 49ers, Carolina Panthers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz - San Francisco 49ers13400.7654502778-1-05-3-06-0-01.00010-2-00.83310W5-0-0
Carolina Panthers71000.4123473745-4-02-6-04-2-00.6676-6-00.5001W3-2-0

San Francisco 49ers & Carolina Panthers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

San Francisco 49ers Futures Odds
2023-24 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers
49ers
Carolina Panthers Futures Odds

No Super Bowl TM Carolina Panthers YR: futures available

San Francisco 49ers & Carolina Panthers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco 49ers vs Carolina Panthers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 9th, 2022 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Carolina Panthers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Carolina Panthers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other October 9, 2022 NFL Games

Matchup
New York Giants vs
Green Bay Packers
Miami Dolphins vs
New York Jets
Tennessee Titans vs
Washington Commanders
Seattle Seahawks vs
New Orleans Saints
Detroit Lions vs
New England Patriots
Chicago Bears vs
Minnesota Vikings
Houston Texans vs
Jacksonville Jaguars
Los Angeles Chargers vs
Cleveland Browns
Pittsburgh Steelers vs
Buffalo Bills
Atlanta Falcons vs
Tampa Bay Buccaneers
Philadelphia Eagles vs
Arizona Cardinals
Dallas Cowboys vs
Los Angeles Rams
Cincinnati Bengals vs
Baltimore Ravens
Odds Preview 754