The 49ers will play the Panthers on Sunday, October 9th, 2022. The matchup takes place at Bank of America Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best 49ers at Panthers Odds
| Underdog Carolina Panthers | Favorite San Francisco 49ers |
|---|---|
| Over | Under |
|---|---|
| Underdog Carolina Panthers | Favorite San Francisco 49ers |
|---|---|
Matchup Odds FAQs
The San Francisco 49ers are -6.5 -109 point spread favorites at BetRivers, while the Carolina Panthers are +6.5 -110 point spread underdogs at BetMGM.
The best over line is 40 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 40 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco 49ers are the -275 moneyline favorite at BetMGM and the Carolina Panthers are the +235 moneyline underdog at BetRivers.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
49ers
Panthers
10/09/22 4:05pm EDT | -6.5 -110+6.5 -110 |
Underdog Carolina Panthers - Carolina Panthers bettors risk $100 to win $90.91 at -110 odds.
A +6.5 Carolina Panthers underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.
A -6.5 San Francisco 49ers favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
San Francisco 49ers at Carolina Panthers Prop Bets
| BetMGM Bet |
|
|---|---|
49ers
Panthers
10/09/22 4:05pm EDT | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2022 Week 5 | 49ers vs Panthers Sunday, October 9th, 2022 | SF 37, CAR 15 Bank of America Stadium | 49ers by 22 |
| 2019 Week 8 | Panthers vs 49ers Sunday, October 27th, 2019 | SF 51, CAR 13 Levi's Stadium | 49ers by 38 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz - San Francisco 49ers | 13 | 4 | 0 | 0.765 | 450 | 277 | 8-1-0 | 5-3-0 | 6-0-0 | 1.000 | 10-2-0 | 0.833 | 10W | 5-0-0 |
| Carolina Panthers | 7 | 10 | 0 | 0.412 | 347 | 374 | 5-4-0 | 2-6-0 | 4-2-0 | 0.667 | 6-6-0 | 0.500 | 1W | 3-2-0 |
San Francisco 49ers & Carolina Panthers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
San Francisco 49ers Futures Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| 49ers | +600 Bet | +550 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| Panthers | +25000 Bet | +20000 Bet |
San Francisco 49ers & Carolina Panthers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco 49ers vs Carolina Panthers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 9th, 2022 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Carolina Panthers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Carolina Panthers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.