The White Sox will play the Nationals on Sunday, September 28th, 2025. Your timezone's first pitch time is 3:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best White Sox at Nationals Odds

**Best Moneyline Betting Odds**
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Moneyline odds are updating, please check back soon.

**Best Total Betting Odds**
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**Best Run Line Betting Odds**
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Chicago White Sox at Washington Nationals Prop Bets

MLB Prop Bets
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	Bet
White Sox Nationals 9/28/25 3:05pm EDT	Pending

Chicago White Sox & Washington Nationals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago White Sox World Series Odds

No World Series TM Chicago White Sox YR: futures available

Washington Nationals World Series Odds

No World Series TM Washington Nationals YR: futures available

Chicago White Sox & Washington Nationals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Chicago White Sox, Washington Nationals
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
e - Washington Nationals	66	96	0.407	+31.0	32-49	34-47	687	899	-212	L1	4-6
e - Chicago White Sox	60	102	0.370	+37.0	33-48	27-54	647	742	-95	W1	3-7

How to Bet on the Game

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How to Bet on the Chicago White Sox vs Washington Nationals MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 28th, 2025 at 3:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Chicago White Sox vs Washington Nationals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago White Sox vs Washington Nationals Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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Chicago White Sox vs Washington Nationals Odds

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