The Guardians will play the Twins on Saturday, September 12th, 2026. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Guardians at Twins Odds
| Underdog Minnesota Twins | Favorite Cleveland Guardians |
|---|---|
| Over | Under |
|---|---|
| Underdog Minnesota Twins | Favorite Cleveland Guardians |
|---|---|
Matchup Odds FAQs
The Cleveland Guardians are the -110 moneyline favorite at BetRivers and the Minnesota Twins are the -108 moneyline underdog at BetRivers.
The best over line is 8.5 -108 runs at BetRivers, which means you risk $108 to win $100 betting the over. The best under line is 8.5 -114 runs at BetRivers, and that means you risk $114 to win $100 betting the under.
The Cleveland Guardians are -1.5 +148 run line favorites at BetRivers, while the Minnesota Twins are +1.5 -182 run line underdogs at BetRivers.
MLB Odds Example
|
Game |
 BetRiversBet |
|---|---|
Guardians
Twins
9/12/26 4:10pm EDT | -110-108 |
- Minnesota Twins bettors risk $100 to win $92.59 at -108 odds. The implied probability for Minnesota Twins is 51.92%.
- Cleveland Guardians bettors risk $100 to win $90.91 at -110 odds. The implied probability for Cleveland Guardians is 52.38%.
Cleveland Guardians at Minnesota Twins Prop Bets
| BetRivers Bet |
|
|---|---|
Guardians
Twins
9/12/26 4:10pm EDT | Pending BetRivers |
Cleveland Guardians & Minnesota Twins Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Cleveland Guardians World Series Odds|
Team | BetRivers |
|---|---|
| Guardians | +1800 Bet |
No World Series TM Minnesota Twins YR: futures available
Cleveland Guardians & Minnesota Twins Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| x - Cleveland Guardians | 85 | 77 | 0.525 | +18.0 | 41-40 | 44-37 | 678 | 667 | +11 | L1 | 8-2 |
| e - Minnesota Twins | 77 | 85 | 0.475 | +26.0 | 42-39 | 35-46 | 739 | 797 | -58 | W1 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Cleveland Guardians vs Minnesota Twins MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 12th, 2026 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs Minnesota Twins Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs Minnesota Twins Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 12, 2026 MLB Games
- Colorado Rockies vs Detroit Tigers
- New York Mets vs New York Yankees
- Pittsburgh Pirates vs Chicago Cubs
- Baltimore Orioles vs Toronto Blue Jays
- San Diego Padres vs San Francisco Giants
- Los Angeles Angels vs Washington Nationals
- Los Angeles Dodgers vs Miami Marlins
- Kansas City Royals vs Boston Red Sox
- Houston Astros vs Tampa Bay Rays
- Cincinnati Reds vs Milwaukee Brewers
- Philadelphia Phillies vs Atlanta Braves
- Chicago White Sox vs St. Louis Cardinals
- Texas Rangers vs Arizona Diamondbacks
- Seattle Mariners vs Oakland Athletics