Detroit Tigers vs Chicago Cubs Odds

The Tigers will play the Cubs on Wednesday, July 22nd, 2026. Your timezone's first pitch time is 8:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2026 season continues, the Detroit Tigers possess a 91.00 SportsBetting3.com power ranking. The Chicago Cubs now have a 95.67 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Detroit Tigers - The Detroit Tigers head into this matchup with a 20-30 record as a visiting team. This standing ranks them 13th Overall for visiting team wins.
  • Home Chicago Cubs - The Chicago Cubs will throw the first pitch possessing a 29-21 home team record. That puts them 5th for home team wins in the Overall MLB standings.
  • Runs Scored - Detroit Tigers batters have produced 426 runs, ranking them 20th Overall, with the Chicago Cubs ranking 5th (508) for runs scored.
  • Runs Allowed - Detroit Tigers pitchers and fielders have allowed 393 runs, ranking them 23rd Overall for runs allowed. Meanwhile, the Chicago Cubs now rank 16th Overall, allowing 448 runs.
  • Team Streaks - The Detroit Tigers won their last game. Their opponent, the Chicago Cubs lost their last game.
  • Team Records - Let's review each team's records. The Detroit Tigers have a 47-53 Overall record (6.5 GB American Central Division), with the Chicago Cubs notching a 56-44 Overall standing (7.0 GB National Central Division).

Best Tigers at Cubs Odds


Best Moneyline Betting Odds
Underdog

Detroit Tigers
Favorite

Chicago Cubs
The Chicago Cubs are the -113 moneyline favorite. Risk $113 to win $100 on the Chicago Cubs at BetRivers. The Detroit Tigers are the -104 underdog at BetRivers. Risk $104 to win $100 on the Detroit Tigers. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 5.5 runs. Risk $420 to win $100. BetRivers has the best under line of 5.5 runs. Risk $100 to win $245. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Chicago Cubs
Favorite

Detroit Tigers
The Detroit Tigers have a -2.5 +255 run line at BetRivers PA. They are the run line favorite in this matchup. The Chicago Cubs have a +2.5 -400 run line at BetRivers PA. The Chicago Cubs are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Detroit Tigers vs Chicago Cubs MLB game on Wednesday, July 22nd, 2026?

The Chicago Cubs are the -113 moneyline favorite at BetRivers and the Detroit Tigers are the -104 moneyline underdog at BetRivers.

What is the over-under total line for the Detroit Tigers vs Chicago Cubs MLB game on Wednesday, July 22nd, 2026?

The best over line is 5.5 -420 runs at BetRivers, which means you risk $420 to win $100 betting the over. The best under line is 5.5 +245 runs at BetRivers, and that means you risk $100 to win $245 betting the under.

What is the run line for the Detroit Tigers vs Chicago Cubs MLB game on Wednesday, July 22nd, 2026?

The Detroit Tigers are -2.5 +255 run line favorites at BetRivers, while the Chicago Cubs are +2.5 -400 run line underdogs at BetRivers.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Tigers
Cubs
7/22/26 8:10pm EDT
-104-113
Bet $100 at BetRivers Pennsylvania
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Possible Moneyline Outcomes
  • Detroit Tigers bettors risk $100 to win $96.15 at -104 odds. The implied probability for Detroit Tigers is 50.98%.
  • Chicago Cubs bettors risk $100 to win $88.5 at -113 odds. The implied probability for Chicago Cubs is 53.05%.

Detroit Tigers at Chicago Cubs Prop Bets

MLB Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Tigers
Cubs
Tie
1st Inning Winner
7/22/26 8:10pm EDT
+310+320-152Bet
Cubs
Total Runs
DET at CUB
7/22/26 8:10pm EDT
3.5 o -1373.5 u +108Bet
Tigers
Total Runs
DET at CUB
7/22/26 8:10pm EDT
3.5 o -1413.5 u +112Bet

Detroit Tigers & Chicago Cubs Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Detroit Tigers World Series Odds
2026 Detroit Tigers World Series Odds

Team
VA,US mlb Evnum: 1 Odds Pending
Chicago Cubs World Series Odds
2026 Chicago Cubs World Series Odds

Team
VA,US mlb Evnum: 1 Odds Pending

Detroit Tigers & Chicago Cubs Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Detroit Tigers, Chicago Cubs
Team W L Pct GB Home Away RS RA Diff Strk L10
Chicago Cubs72530.576+5.036-2636-27645545+100L26-4
Detroit Tigers60640.484+16.532-3128-33565482+83L35-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Detroit Tigers vs Chicago Cubs MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, July 22nd, 2026 at 8:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Detroit Tigers vs Chicago Cubs Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Detroit Tigers vs Chicago Cubs Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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