The Giants will play the Royals on Wednesday, July 22nd, 2026. Your timezone's first pitch time is 2:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
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 #1 BetRiversREVIEW | New Customers - 2nd Chance Bet up to $500 - Code: SPORTS Bet Now 21+ Playable in PA only Gambling Problem? Call 1-800-GAMBLER |
Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Giants at Royals Odds
| Underdog Kansas City Royals | Favorite San Francisco Giants |
|---|---|
| Over | Under |
|---|---|
| Underdog Kansas City Royals | Favorite San Francisco Giants |
|---|---|
Matchup Odds FAQs
The San Francisco Giants are the -120 moneyline favorite at BetRivers and the Kansas City Royals are the +102 moneyline underdog at BetRivers.
The best over line is 5.5 -500 runs at BetRivers, which means you risk $500 to win $100 betting the over. The best under line is 5.5 +280 runs at BetRivers, and that means you risk $100 to win $280 betting the under.
The San Francisco Giants are -2.5 +220 run line favorites at BetRivers, while the Kansas City Royals are +2.5 -315 run line underdogs at BetRivers.
MLB Odds Example
|
Game |
 BetRiversBet |
|---|---|
Giants
Royals
7/22/26 2:10pm EDT | -120+102 |
- Kansas City Royals bettors risk $100 to win $102 at +102 odds. The implied probability for Kansas City Royals is 49.5%.
- San Francisco Giants bettors risk $100 to win $83.33 at -120 odds. The implied probability for San Francisco Giants is 54.55%.
San Francisco Giants at Kansas City Royals Prop Bets
| BetRivers Bet |
|
|---|---|
Giants
Royals
Tie
1st Inning Winner
7/22/26 2:10pm EDT | +300+300-139Bet |
Giants
Royals
Tie
First 3 Innings Winner
7/22/26 2:10pm EDT | +133+150+275Bet |
Royals
Total Runs
SFO at KAN 7/22/26 2:10pm EDT | 3.5 o -1363.5 u +108Bet |
Giants
Total Runs
SFO at KAN 7/22/26 2:10pm EDT | 4.5 o +1054.5 u -134Bet |
| BetRivers | |
Landen Roupp
Strikeouts Thrown
SFO at KAN 7/22/26 2:10pm EDT | 4.5 o -1674.5 u +125Bet |
Seth Lugo
Strikeouts Thrown
SFO at KAN 7/22/26 2:10pm EDT | 4.5 o -1084.5 u -124Bet |
San Francisco Giants & Kansas City Royals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Francisco Giants World Series Odds|
Team |
|---|
| VA,US mlb Evnum: 1 Odds Pending |
|
Team |
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| VA,US mlb Evnum: 1 Odds Pending |
San Francisco Giants & Kansas City Royals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Kansas City Royals | 64 | 81 | 0.441 | +25.0 | 38-35 | 26-46 | 621 | 710 | -89 | L1 | 4-6 |
| e - San Francisco Giants | 59 | 85 | 0.410 | +29.5 | 33-36 | 26-49 | 603 | 678 | -75 | L1 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco Giants vs Kansas City Royals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, July 22nd, 2026 at 2:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Kansas City Royals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Kansas City Royals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other July 22, 2026 MLB Games
- New York Mets vs Milwaukee Brewers
- Washington Nationals vs Colorado Rockies
- Oakland Athletics vs Arizona Diamondbacks
- Cincinnati Reds vs Seattle Mariners
- St. Louis Cardinals vs Los Angeles Angels
- Los Angeles Dodgers vs Philadelphia Phillies
- Minnesota Twins vs Cleveland Guardians
- Pittsburgh Pirates vs New York Yankees
- Tampa Bay Rays vs Toronto Blue Jays
- Baltimore Orioles vs Boston Red Sox
- San Diego Padres vs Atlanta Braves
- Chicago White Sox vs Texas Rangers
- Detroit Tigers vs Chicago Cubs
- Miami Marlins vs Houston Astros